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PP185_ARATH
ID   PP185_ARATH             Reviewed;         627 AA.
AC   O64766;
DT   16-DEC-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1998, sequence version 1.
DT   25-MAY-2022, entry version 118.
DE   RecName: Full=Pentatricopeptide repeat-containing protein At2g35030, mitochondrial;
DE   Flags: Precursor;
GN   Name=PCMP-E15; OrderedLocusNames=At2g35030; ORFNames=F19I3.26;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10617197; DOI=10.1038/45471;
RA   Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA   Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA   Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA   Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA   Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA   Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA   Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT   "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL   Nature 402:761-768(1999).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RA   De Los Reyes C., Quan R., Chen H., Bautista V.R., Kim C.J., Ecker J.R.;
RT   "Arabidopsis ORF clones.";
RL   Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases.
RN   [4]
RP   GENE FAMILY.
RX   PubMed=10809006; DOI=10.1023/a:1006352315928;
RA   Aubourg S., Boudet N., Kreis M., Lecharny A.;
RT   "In Arabidopsis thaliana, 1% of the genome codes for a novel protein family
RT   unique to plants.";
RL   Plant Mol. Biol. 42:603-613(2000).
RN   [5]
RP   GENE FAMILY.
RX   PubMed=15269332; DOI=10.1105/tpc.104.022236;
RA   Lurin C., Andres C., Aubourg S., Bellaoui M., Bitton F., Bruyere C.,
RA   Caboche M., Debast C., Gualberto J., Hoffmann B., Lecharny A., Le Ret M.,
RA   Martin-Magniette M.-L., Mireau H., Peeters N., Renou J.-P., Szurek B.,
RA   Taconnat L., Small I.;
RT   "Genome-wide analysis of Arabidopsis pentatricopeptide repeat proteins
RT   reveals their essential role in organelle biogenesis.";
RL   Plant Cell 16:2089-2103(2004).
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the PPR family. PCMP-E subfamily. {ECO:0000305}.
CC   -!- WEB RESOURCE: Name=Pentatricopeptide repeat proteins;
CC       URL="https://ppr.plantenergy.uwa.edu.au";
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DR   EMBL; AC004238; AAC12843.1; -; Genomic_DNA.
DR   EMBL; CP002685; AEC09051.1; -; Genomic_DNA.
DR   EMBL; BT046115; ACI46503.1; -; mRNA.
DR   PIR; T00484; T00484.
DR   RefSeq; NP_181048.1; NM_129055.4.
DR   AlphaFoldDB; O64766; -.
DR   SMR; O64766; -.
DR   iPTMnet; O64766; -.
DR   PaxDb; O64766; -.
DR   PRIDE; O64766; -.
DR   ProteomicsDB; 249079; -.
DR   EnsemblPlants; AT2G35030.1; AT2G35030.1; AT2G35030.
DR   GeneID; 818067; -.
DR   Gramene; AT2G35030.1; AT2G35030.1; AT2G35030.
DR   KEGG; ath:AT2G35030; -.
DR   Araport; AT2G35030; -.
DR   TAIR; locus:2044797; AT2G35030.
DR   eggNOG; KOG4197; Eukaryota.
DR   HOGENOM; CLU_002706_30_5_1; -.
DR   InParanoid; O64766; -.
DR   OMA; GLELFWK; -.
DR   OrthoDB; 1344243at2759; -.
DR   PhylomeDB; O64766; -.
DR   PRO; PR:O64766; -.
DR   Proteomes; UP000006548; Chromosome 2.
DR   ExpressionAtlas; O64766; baseline and differential.
DR   Genevisible; O64766; AT.
DR   GO; GO:0043231; C:intracellular membrane-bounded organelle; IBA:GO_Central.
DR   GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR   GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR   GO; GO:0009451; P:RNA modification; IBA:GO_Central.
DR   Gene3D; 1.25.40.10; -; 5.
DR   InterPro; IPR002885; Pentatricopeptide_repeat.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   Pfam; PF01535; PPR; 7.
DR   Pfam; PF13041; PPR_2; 3.
DR   SUPFAM; SSF48452; SSF48452; 2.
DR   TIGRFAMs; TIGR00756; PPR; 9.
DR   PROSITE; PS51375; PPR; 15.
PE   2: Evidence at transcript level;
KW   Mitochondrion; Reference proteome; Repeat; Transit peptide.
FT   TRANSIT         1..44
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           45..627
FT                   /note="Pentatricopeptide repeat-containing protein
FT                   At2g35030, mitochondrial"
FT                   /id="PRO_0000356044"
FT   REPEAT          45..75
FT                   /note="PPR 1"
FT   REPEAT          76..110
FT                   /note="PPR 2"
FT   REPEAT          111..138
FT                   /note="PPR 3"
FT   REPEAT          139..173
FT                   /note="PPR 4"
FT   REPEAT          174..200
FT                   /note="PPR 5"
FT   REPEAT          201..235
FT                   /note="PPR 6"
FT   REPEAT          236..262
FT                   /note="PPR 7"
FT   REPEAT          263..293
FT                   /note="PPR 8"
FT   REPEAT          294..328
FT                   /note="PPR 9"
FT   REPEAT          330..360
FT                   /note="PPR 10"
FT   REPEAT          365..396
FT                   /note="PPR 11"
FT   REPEAT          398..432
FT                   /note="PPR 12"
FT   REPEAT          433..467
FT                   /note="PPR 13"
FT   REPEAT          469..499
FT                   /note="PPR 14"
FT   REGION          504..579
FT                   /note="Type E motif"
FT   REGION          580..610
FT                   /note="Type E(+) motif"
SQ   SEQUENCE   627 AA;  71410 MW;  27BDA2EC168AF949 CRC64;
     MQSRALSRLR SYYKRSSVFP SSDNDRSVQL FNLVRSIYSS SSRPRVPQPE WLIGELCKVG
     KIAEARKLFD GLPERDVVTW THVITGYIKL GDMREARELF DRVDSRKNVV TWTAMVSGYL
     RSKQLSIAEM LFQEMPERNV VSWNTMIDGY AQSGRIDKAL ELFDEMPERN IVSWNSMVKA
     LVQRGRIDEA MNLFERMPRR DVVSWTAMVD GLAKNGKVDE ARRLFDCMPE RNIISWNAMI
     TGYAQNNRID EADQLFQVMP ERDFASWNTM ITGFIRNREM NKACGLFDRM PEKNVISWTT
     MITGYVENKE NEEALNVFSK MLRDGSVKPN VGTYVSILSA CSDLAGLVEG QQIHQLISKS
     VHQKNEIVTS ALLNMYSKSG ELIAARKMFD NGLVCQRDLI SWNSMIAVYA HHGHGKEAIE
     MYNQMRKHGF KPSAVTYLNL LFACSHAGLV EKGMEFFKDL VRDESLPLRE EHYTCLVDLC
     GRAGRLKDVT NFINCDDARL SRSFYGAILS ACNVHNEVSI AKEVVKKVLE TGSDDAGTYV
     LMSNIYAANG KREEAAEMRM KMKEKGLKKQ PGCSWVKVGK QNHLFVVGDK SHPQFEALDS
     ILSDLRNKMR KNKNVTSDAE EAEFLVI
 
 
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