PP185_ARATH
ID PP185_ARATH Reviewed; 627 AA.
AC O64766;
DT 16-DEC-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-AUG-1998, sequence version 1.
DT 25-MAY-2022, entry version 118.
DE RecName: Full=Pentatricopeptide repeat-containing protein At2g35030, mitochondrial;
DE Flags: Precursor;
GN Name=PCMP-E15; OrderedLocusNames=At2g35030; ORFNames=F19I3.26;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA De Los Reyes C., Quan R., Chen H., Bautista V.R., Kim C.J., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP GENE FAMILY.
RX PubMed=10809006; DOI=10.1023/a:1006352315928;
RA Aubourg S., Boudet N., Kreis M., Lecharny A.;
RT "In Arabidopsis thaliana, 1% of the genome codes for a novel protein family
RT unique to plants.";
RL Plant Mol. Biol. 42:603-613(2000).
RN [5]
RP GENE FAMILY.
RX PubMed=15269332; DOI=10.1105/tpc.104.022236;
RA Lurin C., Andres C., Aubourg S., Bellaoui M., Bitton F., Bruyere C.,
RA Caboche M., Debast C., Gualberto J., Hoffmann B., Lecharny A., Le Ret M.,
RA Martin-Magniette M.-L., Mireau H., Peeters N., Renou J.-P., Szurek B.,
RA Taconnat L., Small I.;
RT "Genome-wide analysis of Arabidopsis pentatricopeptide repeat proteins
RT reveals their essential role in organelle biogenesis.";
RL Plant Cell 16:2089-2103(2004).
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the PPR family. PCMP-E subfamily. {ECO:0000305}.
CC -!- WEB RESOURCE: Name=Pentatricopeptide repeat proteins;
CC URL="https://ppr.plantenergy.uwa.edu.au";
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DR EMBL; AC004238; AAC12843.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC09051.1; -; Genomic_DNA.
DR EMBL; BT046115; ACI46503.1; -; mRNA.
DR PIR; T00484; T00484.
DR RefSeq; NP_181048.1; NM_129055.4.
DR AlphaFoldDB; O64766; -.
DR SMR; O64766; -.
DR iPTMnet; O64766; -.
DR PaxDb; O64766; -.
DR PRIDE; O64766; -.
DR ProteomicsDB; 249079; -.
DR EnsemblPlants; AT2G35030.1; AT2G35030.1; AT2G35030.
DR GeneID; 818067; -.
DR Gramene; AT2G35030.1; AT2G35030.1; AT2G35030.
DR KEGG; ath:AT2G35030; -.
DR Araport; AT2G35030; -.
DR TAIR; locus:2044797; AT2G35030.
DR eggNOG; KOG4197; Eukaryota.
DR HOGENOM; CLU_002706_30_5_1; -.
DR InParanoid; O64766; -.
DR OMA; GLELFWK; -.
DR OrthoDB; 1344243at2759; -.
DR PhylomeDB; O64766; -.
DR PRO; PR:O64766; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; O64766; baseline and differential.
DR Genevisible; O64766; AT.
DR GO; GO:0043231; C:intracellular membrane-bounded organelle; IBA:GO_Central.
DR GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR GO; GO:0009451; P:RNA modification; IBA:GO_Central.
DR Gene3D; 1.25.40.10; -; 5.
DR InterPro; IPR002885; Pentatricopeptide_repeat.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR Pfam; PF01535; PPR; 7.
DR Pfam; PF13041; PPR_2; 3.
DR SUPFAM; SSF48452; SSF48452; 2.
DR TIGRFAMs; TIGR00756; PPR; 9.
DR PROSITE; PS51375; PPR; 15.
PE 2: Evidence at transcript level;
KW Mitochondrion; Reference proteome; Repeat; Transit peptide.
FT TRANSIT 1..44
FT /note="Mitochondrion"
FT /evidence="ECO:0000255"
FT CHAIN 45..627
FT /note="Pentatricopeptide repeat-containing protein
FT At2g35030, mitochondrial"
FT /id="PRO_0000356044"
FT REPEAT 45..75
FT /note="PPR 1"
FT REPEAT 76..110
FT /note="PPR 2"
FT REPEAT 111..138
FT /note="PPR 3"
FT REPEAT 139..173
FT /note="PPR 4"
FT REPEAT 174..200
FT /note="PPR 5"
FT REPEAT 201..235
FT /note="PPR 6"
FT REPEAT 236..262
FT /note="PPR 7"
FT REPEAT 263..293
FT /note="PPR 8"
FT REPEAT 294..328
FT /note="PPR 9"
FT REPEAT 330..360
FT /note="PPR 10"
FT REPEAT 365..396
FT /note="PPR 11"
FT REPEAT 398..432
FT /note="PPR 12"
FT REPEAT 433..467
FT /note="PPR 13"
FT REPEAT 469..499
FT /note="PPR 14"
FT REGION 504..579
FT /note="Type E motif"
FT REGION 580..610
FT /note="Type E(+) motif"
SQ SEQUENCE 627 AA; 71410 MW; 27BDA2EC168AF949 CRC64;
MQSRALSRLR SYYKRSSVFP SSDNDRSVQL FNLVRSIYSS SSRPRVPQPE WLIGELCKVG
KIAEARKLFD GLPERDVVTW THVITGYIKL GDMREARELF DRVDSRKNVV TWTAMVSGYL
RSKQLSIAEM LFQEMPERNV VSWNTMIDGY AQSGRIDKAL ELFDEMPERN IVSWNSMVKA
LVQRGRIDEA MNLFERMPRR DVVSWTAMVD GLAKNGKVDE ARRLFDCMPE RNIISWNAMI
TGYAQNNRID EADQLFQVMP ERDFASWNTM ITGFIRNREM NKACGLFDRM PEKNVISWTT
MITGYVENKE NEEALNVFSK MLRDGSVKPN VGTYVSILSA CSDLAGLVEG QQIHQLISKS
VHQKNEIVTS ALLNMYSKSG ELIAARKMFD NGLVCQRDLI SWNSMIAVYA HHGHGKEAIE
MYNQMRKHGF KPSAVTYLNL LFACSHAGLV EKGMEFFKDL VRDESLPLRE EHYTCLVDLC
GRAGRLKDVT NFINCDDARL SRSFYGAILS ACNVHNEVSI AKEVVKKVLE TGSDDAGTYV
LMSNIYAANG KREEAAEMRM KMKEKGLKKQ PGCSWVKVGK QNHLFVVGDK SHPQFEALDS
ILSDLRNKMR KNKNVTSDAE EAEFLVI