PP199_ARATH
ID PP199_ARATH Reviewed; 822 AA.
AC Q8RWS8; O22948;
DT 16-DEC-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2002, sequence version 1.
DT 03-AUG-2022, entry version 117.
DE RecName: Full=Pentatricopeptide repeat-containing protein At2g41720;
DE AltName: Full=Protein EMBRYO DEFECTIVE 2654;
GN Name=EMB2654; OrderedLocusNames=At2g41720; ORFNames=T11A7.18;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP GENE FAMILY.
RX PubMed=15269332; DOI=10.1105/tpc.104.022236;
RA Lurin C., Andres C., Aubourg S., Bellaoui M., Bitton F., Bruyere C.,
RA Caboche M., Debast C., Gualberto J., Hoffmann B., Lecharny A., Le Ret M.,
RA Martin-Magniette M.-L., Mireau H., Peeters N., Renou J.-P., Szurek B.,
RA Taconnat L., Small I.;
RT "Genome-wide analysis of Arabidopsis pentatricopeptide repeat proteins
RT reveals their essential role in organelle biogenesis.";
RL Plant Cell 16:2089-2103(2004).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=1;
CC Comment=A number of isoforms are produced. According to EST
CC sequences.;
CC Name=1;
CC IsoId=Q8RWS8-1; Sequence=Displayed;
CC -!- SIMILARITY: Belongs to the PPR family. P subfamily. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAC02776.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC -!- WEB RESOURCE: Name=Pentatricopeptide repeat proteins;
CC URL="https://ppr.plantenergy.uwa.edu.au";
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DR EMBL; AC002339; AAC02776.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002685; AEC10025.1; -; Genomic_DNA.
DR EMBL; AY091135; AAM14084.1; -; mRNA.
DR EMBL; AY117242; AAM51317.1; -; mRNA.
DR PIR; C84845; C84845.
DR RefSeq; NP_850356.1; NM_180025.2. [Q8RWS8-1]
DR AlphaFoldDB; Q8RWS8; -.
DR SMR; Q8RWS8; -.
DR BioGRID; 4108; 2.
DR IntAct; Q8RWS8; 2.
DR STRING; 3702.AT2G41720.1; -.
DR iPTMnet; Q8RWS8; -.
DR PaxDb; Q8RWS8; -.
DR PRIDE; Q8RWS8; -.
DR ProteomicsDB; 249160; -. [Q8RWS8-1]
DR EnsemblPlants; AT2G41720.1; AT2G41720.1; AT2G41720. [Q8RWS8-1]
DR GeneID; 818771; -.
DR Gramene; AT2G41720.1; AT2G41720.1; AT2G41720. [Q8RWS8-1]
DR KEGG; ath:AT2G41720; -.
DR Araport; AT2G41720; -.
DR TAIR; locus:2054331; AT2G41720.
DR eggNOG; KOG4197; Eukaryota.
DR InParanoid; Q8RWS8; -.
DR PhylomeDB; Q8RWS8; -.
DR PRO; PR:Q8RWS8; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q8RWS8; baseline and differential.
DR Genevisible; Q8RWS8; AT.
DR GO; GO:0009507; C:chloroplast; IEA:GOC.
DR GO; GO:0003735; F:structural constituent of ribosome; IMP:TAIR.
DR GO; GO:0010239; P:chloroplast mRNA processing; IMP:TAIR.
DR GO; GO:0009793; P:embryo development ending in seed dormancy; IMP:TAIR.
DR GO; GO:0008380; P:RNA splicing; IMP:TAIR.
DR Gene3D; 1.25.40.10; -; 7.
DR InterPro; IPR002885; Pentatricopeptide_repeat.
DR InterPro; IPR033443; PPR_long.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR Pfam; PF01535; PPR; 1.
DR Pfam; PF13041; PPR_2; 2.
DR Pfam; PF13812; PPR_3; 4.
DR Pfam; PF17177; PPR_long; 1.
DR SUPFAM; SSF48452; SSF48452; 1.
DR TIGRFAMs; TIGR00756; PPR; 13.
DR PROSITE; PS51375; PPR; 18.
PE 2: Evidence at transcript level;
KW Alternative splicing; Reference proteome; Repeat.
FT CHAIN 1..822
FT /note="Pentatricopeptide repeat-containing protein
FT At2g41720"
FT /id="PRO_0000356058"
FT REPEAT 106..136
FT /note="PPR 1"
FT REPEAT 142..176
FT /note="PPR 2"
FT REPEAT 177..211
FT /note="PPR 3"
FT REPEAT 212..246
FT /note="PPR 4"
FT REPEAT 247..281
FT /note="PPR 5"
FT REPEAT 282..316
FT /note="PPR 6"
FT REPEAT 319..353
FT /note="PPR 7"
FT REPEAT 354..388
FT /note="PPR 8"
FT REPEAT 389..423
FT /note="PPR 9"
FT REPEAT 424..458
FT /note="PPR 10"
FT REPEAT 459..493
FT /note="PPR 11"
FT REPEAT 494..528
FT /note="PPR 12"
FT REPEAT 529..563
FT /note="PPR 13"
FT REPEAT 564..598
FT /note="PPR 14"
FT REPEAT 599..633
FT /note="PPR 15"
FT REPEAT 634..668
FT /note="PPR 16"
FT REPEAT 669..699
FT /note="PPR 17"
FT REPEAT 704..738
FT /note="PPR 18"
FT REPEAT 739..773
FT /note="PPR 19"
FT REGION 1..28
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 822 AA; 92414 MW; B67C530B407AC63B CRC64;
MATVTNFKLV TPPESSRADK PGATKASDAF QEKKSVSVNY DRGEHEVSVN IGGLRKADIP
RRYRIRVEND RFQKDWSVSE VVDRLMALNR WEEVDGVLNS WVGRFARKNF PVLIRELSRR
GCIELCVNVF KWMKIQKNYC ARNDIYNMMI RLHARHNWVD QARGLFFEMQ KWSCKPDAET
YDALINAHGR AGQWRWAMNL MDDMLRAAIA PSRSTYNNLI NACGSSGNWR EALEVCKKMT
DNGVGPDLVT HNIVLSAYKS GRQYSKALSY FELMKGAKVR PDTTTFNIII YCLSKLGQSS
QALDLFNSMR EKRAECRPDV VTFTSIMHLY SVKGEIENCR AVFEAMVAEG LKPNIVSYNA
LMGAYAVHGM SGTALSVLGD IKQNGIIPDV VSYTCLLNSY GRSRQPGKAK EVFLMMRKER
RKPNVVTYNA LIDAYGSNGF LAEAVEIFRQ MEQDGIKPNV VSVCTLLAAC SRSKKKVNVD
TVLSAAQSRG INLNTAAYNS AIGSYINAAE LEKAIALYQS MRKKKVKADS VTFTILISGS
CRMSKYPEAI SYLKEMEDLS IPLTKEVYSS VLCAYSKQGQ VTEAESIFNQ MKMAGCEPDV
IAYTSMLHAY NASEKWGKAC ELFLEMEANG IEPDSIACSA LMRAFNKGGQ PSNVFVLMDL
MREKEIPFTG AVFFEIFSAC NTLQEWKRAI DLIQMMDPYL PSLSIGLTNQ MLHLFGKSGK
VEAMMKLFYK IIASGVGINL KTYAILLEHL LAVGNWRKYI EVLEWMSGAG IQPSNQMYRD
IISFGERSAG IEFEPLIRQK LESLRNKGEG LIPTFRHEGT LL
