ID   PP1R7_PONAB             Reviewed;         360 AA.
AC   Q5RFS7;
DT   13-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT   21-DEC-2004, sequence version 1.
DT   25-MAY-2022, entry version 78.
DE   RecName: Full=Protein phosphatase 1 regulatory subunit 7;
DE   AltName: Full=Protein phosphatase 1 regulatory subunit 22;
GN   Name=PPP1R7; Synonyms=SDS22;
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Heart;
RG   The German cDNA consortium;
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Regulatory subunit of protein phosphatase 1. {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with PPP1CA, PPP1CB and PPP1CC/PPP1G. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SDS22 family. {ECO:0000305}.
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DR   EMBL; CR857075; CAH89380.1; -; mRNA.
DR   RefSeq; NP_001124579.1; NM_001131107.1.
DR   AlphaFoldDB; Q5RFS7; -.
DR   SMR; Q5RFS7; -.
DR   STRING; 9601.ENSPPYP00000014933; -.
DR   GeneID; 100171414; -.
DR   KEGG; pon:100171414; -.
DR   CTD; 5510; -.
DR   eggNOG; KOG0531; Eukaryota.
DR   InParanoid; Q5RFS7; -.
DR   OrthoDB; 968788at2759; -.
DR   Proteomes; UP000001595; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   Gene3D; 3.80.10.10; -; 2.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR025875; Leu-rich_rpt_4.
DR   InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR003603; U2A'_phosphoprotein32A_C.
DR   Pfam; PF12799; LRR_4; 2.
DR   SMART; SM00369; LRR_TYP; 6.
DR   SMART; SM00446; LRRcap; 1.
DR   PROSITE; PS51450; LRR; 12.
PE   2: Evidence at transcript level;
KW   Acetylation; Leucine-rich repeat; Nucleus; Phosphoprotein;
KW   Reference proteome; Repeat.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000250|UniProtKB:Q15435"
FT   CHAIN           2..360
FT                   /note="Protein phosphatase 1 regulatory subunit 7"
FT                   /id="PRO_0000239615"
FT   REPEAT          77..98
FT                   /note="LRR 1"
FT   REPEAT          99..120
FT                   /note="LRR 2"
FT   REPEAT          121..142
FT                   /note="LRR 3"
FT   REPEAT          143..164
FT                   /note="LRR 4"
FT   REPEAT          165..186
FT                   /note="LRR 5"
FT   REPEAT          187..208
FT                   /note="LRR 6"
FT   REPEAT          209..230
FT                   /note="LRR 7"
FT   REPEAT          231..252
FT                   /note="LRR 8"
FT   REPEAT          253..274
FT                   /note="LRR 9"
FT   REPEAT          275..296
FT                   /note="LRR 10"
FT   REPEAT          297..318
FT                   /note="LRR 11"
FT   DOMAIN          331..360
FT                   /note="LRRCT"
FT   REGION          1..64
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..15
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        16..38
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         2
FT                   /note="N-acetylalanine"
FT                   /evidence="ECO:0000250|UniProtKB:Q15435"
FT   MOD_RES         12
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q15435"
FT   MOD_RES         24
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q15435"
FT   MOD_RES         27
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q15435"
FT   MOD_RES         44
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q15435"
FT   MOD_RES         47
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q15435"
FT   MOD_RES         322
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q15435"
SQ   SEQUENCE   360 AA;  41478 MW;  74D63847AC4FAF1A CRC64;
     MAAERGAGQQ QSQEMMEVDR RVESEESGDE EGKKHSSGIV ADLSEQSLKD GEERGEEDPE
     EEHELPVDME TINLDRDAED VDLNHYRIGK IEGFEVLKKV KTLCLRQNLI KCIENLEELQ
     SLRELDLYDN QIKKIENLEA LTELEILDIS FNLLRNIEGV DKVTQLKKLF LVNNKISKIE
     NLSNLHQLQM LELGSNRIRA IENIDTLTNL ESLFLGKNKI TKLQNLDALT NLTVLSMQSN
     RLTKIEGLQN LVNLQELYLS HNGIEVIEGL ENNNKLTMLD IASNRIKKIE NISHLTEPQE
     FWMNDNLLES WSDLDELKGA RSLETVYLER NPLQKDPQYR RKVMLALPSV RQIDATFVRF