PP222_ARATH
ID PP222_ARATH Reviewed; 778 AA.
AC Q9SF38; Q56XQ4;
DT 16-DEC-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 25-MAY-2022, entry version 108.
DE RecName: Full=Pentatricopeptide repeat-containing protein At3g09650, chloroplastic;
DE AltName: Full=Protein HIGH CHLOROPHYLL FLUORESCENCE 152;
DE Flags: Precursor;
GN Name=HCF152; Synonyms=CRM3; OrderedLocusNames=At3g09650; ORFNames=F11F8_24;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130713; DOI=10.1038/35048706;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP FUNCTION.
RX PubMed=11549768; DOI=10.2307/3871432;
RA Felder S., Meierhoff K., Sane A.P., Meurer J., Driemel C., Pluecken H.,
RA Klaff P., Stein B., Bechtold N., Westhoff P.;
RT "The nucleus-encoded HCF107 gene of Arabidopsis provides a link between
RT intercistronic RNA processing and the accumulation of translation-competent
RT psbH transcripts in chloroplasts.";
RL Plant Cell 13:2127-2141(2001).
RN [5]
RP FUNCTION, AND SUBCELLULAR LOCATION.
RX PubMed=12782738; DOI=10.1105/tpc.010397;
RA Meierhoff K., Felder S., Nakamura T., Bechtold N., Schuster G.;
RT "HCF152, an Arabidopsis RNA binding pentatricopeptide repeat protein
RT involved in the processing of chloroplast psbB-psbT-psbH-petB-petD RNAs.";
RL Plant Cell 15:1480-1495(2003).
RN [6]
RP GENE FAMILY.
RX PubMed=15269332; DOI=10.1105/tpc.104.022236;
RA Lurin C., Andres C., Aubourg S., Bellaoui M., Bitton F., Bruyere C.,
RA Caboche M., Debast C., Gualberto J., Hoffmann B., Lecharny A., Le Ret M.,
RA Martin-Magniette M.-L., Mireau H., Peeters N., Renou J.-P., Szurek B.,
RA Taconnat L., Small I.;
RT "Genome-wide analysis of Arabidopsis pentatricopeptide repeat proteins
RT reveals their essential role in organelle biogenesis.";
RL Plant Cell 16:2089-2103(2004).
CC -!- FUNCTION: Involved in the processing of polycistronic chloroplast psbB-
CC psbT-psbH-petB-petD transcript. Could bind RNA.
CC {ECO:0000269|PubMed:11549768, ECO:0000269|PubMed:12782738}.
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast stroma
CC {ECO:0000269|PubMed:12782738}.
CC -!- SIMILARITY: Belongs to the PPR family. P subfamily. {ECO:0000305}.
CC -!- WEB RESOURCE: Name=Pentatricopeptide repeat proteins;
CC URL="https://ppr.plantenergy.uwa.edu.au";
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DR EMBL; AC016661; AAF23295.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE74793.1; -; Genomic_DNA.
DR EMBL; AK221619; BAD95223.1; -; mRNA.
DR RefSeq; NP_187576.1; NM_111799.4.
DR AlphaFoldDB; Q9SF38; -.
DR SMR; Q9SF38; -.
DR BioGRID; 5456; 3.
DR STRING; 3702.AT3G09650.1; -.
DR PaxDb; Q9SF38; -.
DR PRIDE; Q9SF38; -.
DR ProteomicsDB; 248945; -.
DR EnsemblPlants; AT3G09650.1; AT3G09650.1; AT3G09650.
DR GeneID; 820122; -.
DR Gramene; AT3G09650.1; AT3G09650.1; AT3G09650.
DR KEGG; ath:AT3G09650; -.
DR Araport; AT3G09650; -.
DR TAIR; locus:2074924; AT3G09650.
DR eggNOG; KOG4197; Eukaryota.
DR HOGENOM; CLU_022641_0_0_1; -.
DR InParanoid; Q9SF38; -.
DR OMA; ALVQHYY; -.
DR OrthoDB; 1344243at2759; -.
DR PhylomeDB; Q9SF38; -.
DR PRO; PR:Q9SF38; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q9SF38; baseline and differential.
DR Genevisible; Q9SF38; AT.
DR GO; GO:0009570; C:chloroplast stroma; IDA:TAIR.
DR GO; GO:0003729; F:mRNA binding; IDA:TAIR.
DR GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR GO; GO:0006397; P:mRNA processing; IMP:TAIR.
DR Gene3D; 1.25.40.10; -; 5.
DR InterPro; IPR002885; Pentatricopeptide_repeat.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR Pfam; PF01535; PPR; 2.
DR Pfam; PF12854; PPR_1; 1.
DR Pfam; PF13041; PPR_2; 3.
DR Pfam; PF13812; PPR_3; 1.
DR TIGRFAMs; TIGR00756; PPR; 7.
DR PROSITE; PS51375; PPR; 12.
PE 2: Evidence at transcript level;
KW Chloroplast; Nucleotide-binding; Plastid; Reference proteome; Repeat;
KW RNA-binding; Transit peptide.
FT TRANSIT 1..65
FT /note="Chloroplast"
FT /evidence="ECO:0000255"
FT CHAIN 66..778
FT /note="Pentatricopeptide repeat-containing protein
FT At3g09650, chloroplastic"
FT /id="PRO_0000356081"
FT REPEAT 235..269
FT /note="PPR 1"
FT REPEAT 270..304
FT /note="PPR 2"
FT REPEAT 305..339
FT /note="PPR 3"
FT REPEAT 413..443
FT /note="PPR 4"
FT REPEAT 451..485
FT /note="PPR 5"
FT REPEAT 486..521
FT /note="PPR 6"
FT REPEAT 522..556
FT /note="PPR 7"
FT REPEAT 557..587
FT /note="PPR 8"
FT REPEAT 593..627
FT /note="PPR 9"
FT REPEAT 628..658
FT /note="PPR 10"
FT REGION 351..381
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 352..376
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 184
FT /note="Y -> C (in Ref. 3; BAD95223)"
FT /evidence="ECO:0000305"
FT CONFLICT 204
FT /note="D -> N (in Ref. 3; BAD95223)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 778 AA; 86961 MW; 2483D9EE34F8AE55 CRC64;
MNILRPPTSS SSSSFPPYPK PVSLTPPVSF TLIHNPINLC SINPPFTNAG RPIFQRSASG
TANSSAEDLS SFLGSPSEAY STHNDQELLF LLRNRKTDEA WAKYVQSTHL PGPTCLSRLV
SQLSYQSKPE SLTRAQSILT RLRNERQLHR LDANSLGLLA MAAAKSGQTL YAVSVIKSMI
RSGYLPHVKA WTAAVASLSA SGDDGPEESI KLFIAITRRV KRFGDQSLVG QSRPDTAAFN
AVLNACANLG DTDKYWKLFE EMSEWDCEPD VLTYNVMIKL CARVGRKELI VFVLERIIDK
GIKVCMTTMH SLVAAYVGFG DLRTAERIVQ AMREKRRDLC KVLRECNAED LKEKEEEEAE
DDEDAFEDDE DSGYSARDEV SEEGVVDVFK KLLPNSVDPS GEPPLLPKVF APDSRIYTTL
MKGYMKNGRV ADTARMLEAM RRQDDRNSHP DEVTYTTVVS AFVNAGLMDR ARQVLAEMAR
MGVPANRITY NVLLKGYCKQ LQIDRAEDLL REMTEDAGIE PDVVSYNIII DGCILIDDSA
GALAFFNEMR TRGIAPTKIS YTTLMKAFAM SGQPKLANRV FDEMMNDPRV KVDLIAWNML
VEGYCRLGLI EDAQRVVSRM KENGFYPNVA TYGSLANGVS QARKPGDALL LWKEIKERCA
VKKKEAPSDS SSDPAPPMLK PDEGLLDTLA DICVRAAFFK KALEIIACME ENGIPPNKTK
YKKIYVEMHS RMFTSKHASQ ARIDRRVERK RAAEAFKFWL GLPNSYYGSE WKLGPRED
