PP273_ARATH
ID PP273_ARATH Reviewed; 629 AA.
AC Q9M3A8;
DT 16-DEC-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 25-MAY-2022, entry version 122.
DE RecName: Full=Pentatricopeptide repeat-containing protein At3g49240, mitochondrial;
DE AltName: Full=Protein EMBRYO DEFECTIVE 1796;
DE Flags: Precursor;
GN Name=EMB1796; OrderedLocusNames=At3g49240; ORFNames=F2K15.100;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], AND FUNCTION.
RX PubMed=15647901; DOI=10.1007/s00425-004-1452-x;
RA Cushing D.A., Forsthoefel N.R., Gestaut D.R., Vernon D.M.;
RT "Arabidopsis emb175 and other ppr knockout mutants reveal essential roles
RT for pentatricopeptide repeat (PPR) proteins in plant embryogenesis.";
RL Planta 221:424-436(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130713; DOI=10.1038/35048706;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP GENE FAMILY.
RX PubMed=15269332; DOI=10.1105/tpc.104.022236;
RA Lurin C., Andres C., Aubourg S., Bellaoui M., Bitton F., Bruyere C.,
RA Caboche M., Debast C., Gualberto J., Hoffmann B., Lecharny A., Le Ret M.,
RA Martin-Magniette M.-L., Mireau H., Peeters N., Renou J.-P., Szurek B.,
RA Taconnat L., Small I.;
RT "Genome-wide analysis of Arabidopsis pentatricopeptide repeat proteins
RT reveals their essential role in organelle biogenesis.";
RL Plant Cell 16:2089-2103(2004).
RN [6]
RP IDENTIFICATION BY MASS SPECTROMETRY, AND CLEAVAGE OF TRANSIT PEPTIDE AFTER
RP MET-34.
RX PubMed=25732537; DOI=10.1093/jxb/erv064;
RA Carrie C., Venne A.S., Zahedi R.P., Soll J.;
RT "Identification of cleavage sites and substrate proteins for two
RT mitochondrial intermediate peptidases in Arabidopsis thaliana.";
RL J. Exp. Bot. 66:2691-2708(2015).
CC -!- FUNCTION: May play a role in embryogenesis.
CC {ECO:0000269|PubMed:15647901}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000305|PubMed:25732537}.
CC -!- SIMILARITY: Belongs to the PPR family. P subfamily. {ECO:0000305}.
CC -!- WEB RESOURCE: Name=Pentatricopeptide repeat proteins;
CC URL="https://ppr.plantenergy.uwa.edu.au";
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DR EMBL; AY864352; AAW62967.1; -; mRNA.
DR EMBL; AL132956; CAB66403.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE78514.1; -; Genomic_DNA.
DR EMBL; AY099591; AAM20442.1; -; mRNA.
DR EMBL; BT008786; AAP68225.1; -; mRNA.
DR PIR; T45829; T45829.
DR RefSeq; NP_190493.1; NM_114783.4.
DR AlphaFoldDB; Q9M3A8; -.
DR SMR; Q9M3A8; -.
DR BioGRID; 9403; 4.
DR IntAct; Q9M3A8; 4.
DR STRING; 3702.AT3G49240.1; -.
DR SwissPalm; Q9M3A8; -.
DR PaxDb; Q9M3A8; -.
DR PRIDE; Q9M3A8; -.
DR ProteomicsDB; 249111; -.
DR EnsemblPlants; AT3G49240.1; AT3G49240.1; AT3G49240.
DR GeneID; 824085; -.
DR Gramene; AT3G49240.1; AT3G49240.1; AT3G49240.
DR KEGG; ath:AT3G49240; -.
DR Araport; AT3G49240; -.
DR TAIR; locus:2082871; AT3G49240.
DR eggNOG; KOG4197; Eukaryota.
DR HOGENOM; CLU_012783_0_1_1; -.
DR InParanoid; Q9M3A8; -.
DR OMA; MECYEEA; -.
DR OrthoDB; 1344243at2759; -.
DR PhylomeDB; Q9M3A8; -.
DR PRO; PR:Q9M3A8; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q9M3A8; differential.
DR Genevisible; Q9M3A8; AT.
DR GO; GO:0009507; C:chloroplast; IDA:TAIR.
DR GO; GO:0005739; C:mitochondrion; IDA:TAIR.
DR GO; GO:0005524; F:ATP binding; HDA:TAIR.
DR GO; GO:0009793; P:embryo development ending in seed dormancy; IMP:TAIR.
DR GO; GO:0009960; P:endosperm development; IMP:TAIR.
DR GO; GO:0006349; P:regulation of gene expression by genomic imprinting; IMP:TAIR.
DR Gene3D; 1.25.40.10; -; 3.
DR InterPro; IPR002885; Pentatricopeptide_repeat.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR Pfam; PF01535; PPR; 6.
DR Pfam; PF12854; PPR_1; 1.
DR Pfam; PF13041; PPR_2; 1.
DR Pfam; PF13812; PPR_3; 1.
DR SUPFAM; SSF48452; SSF48452; 1.
DR TIGRFAMs; TIGR00756; PPR; 6.
DR PROSITE; PS51375; PPR; 11.
PE 1: Evidence at protein level;
KW Mitochondrion; Reference proteome; Repeat; Transit peptide.
FT TRANSIT 1..34
FT /note="Mitochondrion"
FT /evidence="ECO:0000269|PubMed:25732537"
FT CHAIN 35..629
FT /note="Pentatricopeptide repeat-containing protein
FT At3g49240, mitochondrial"
FT /id="PRO_0000356132"
FT REPEAT 129..163
FT /note="PPR 1"
FT REPEAT 164..194
FT /note="PPR 2"
FT REPEAT 200..234
FT /note="PPR 3"
FT REPEAT 235..265
FT /note="PPR 4"
FT REPEAT 272..306
FT /note="PPR 5"
FT REPEAT 309..343
FT /note="PPR 6"
FT REPEAT 349..383
FT /note="PPR 7"
FT REPEAT 384..418
FT /note="PPR 8"
FT REPEAT 419..453
FT /note="PPR 9"
FT REPEAT 454..484
FT /note="PPR 10"
FT REPEAT 488..522
FT /note="PPR 11"
FT REGION 44..79
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 59..77
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 629 AA; 71293 MW; AAD1ECDF7B50AC01 CRC64;
MSISKAAFLN HLQTLSRSYR HRVLPQPFLA VRYMSFATQE EAAAERRRRK RRLRMEPPVN
SFNRSQQQQS QIPRPIQNPN IPKLPESVSA LVGKRLDLHN HILKLIREND LEEAALYTRH
SVYSNCRPTI FTVNTVLAAQ LRQAKYGALL QLHGFINQAG IAPNIITYNL IFQAYLDVRK
PEIALEHYKL FIDNAPLNPS IATFRILVKG LVSNDNLEKA MEIKEDMAVK GFVVDPVVYS
YLMMGCVKNS DADGVLKLYQ ELKEKLGGFV DDGVVYGQLM KGYFMKEMEK EAMECYEEAV
GENSKVRMSA MAYNYVLEAL SENGKFDEAL KLFDAVKKEH NPPRHLAVNL GTFNVMVNGY
CAGGKFEEAM EVFRQMGDFK CSPDTLSFNN LMNQLCDNEL LAEAEKLYGE MEEKNVKPDE
YTYGLLMDTC FKEGKIDEGA AYYKTMVESN LRPNLAVYNR LQDQLIKAGK LDDAKSFFDM
MVSKLKMDDE AYKFIMRALS EAGRLDEMLK IVDEMLDDDT VRVSEELQEF VKEELRKGGR
EGDLEKLMEE KERLKAEAKA KELADAEEKK KAQSINIAAL IPPKAVEEKK ETAKLLWENE
AGGVEEADVV EMAKGVEAGG SNGQDPPSC
