ATB13_ARATH
ID ATB13_ARATH Reviewed; 294 AA.
AC Q8LC03; Q9S7A4;
DT 31-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT 31-OCT-2006, sequence version 2.
DT 03-AUG-2022, entry version 125.
DE RecName: Full=Homeobox-leucine zipper protein ATHB-13;
DE AltName: Full=HD-ZIP protein ATHB-13;
DE AltName: Full=Homeodomain transcription factor ATHB-13;
GN Name=ATHB-13; OrderedLocusNames=At1g69780; ORFNames=T6C23.2;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], AND FUNCTION.
RX PubMed=11292072; DOI=10.1023/a:1006464907710;
RA Hanson J., Johannesson H., Engstroem P.;
RT "Sugar-dependent alterations in cotyledon and leaf development in
RT transgenic plants expressing the HDZhdip gene ATHB13.";
RL Plant Mol. Biol. 45:247-262(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP GENE FAMILY, AND TISSUE SPECIFICITY.
RX PubMed=16055682; DOI=10.1104/pp.105.063461;
RA Henriksson E., Olsson A.S.B., Johannesson H., Johansson H., Hanson J.,
RA Engstroem P., Soederman E.;
RT "Homeodomain leucine zipper class I genes in Arabidopsis. Expression
RT patterns and phylogenetic relationships.";
RL Plant Physiol. 139:509-518(2005).
CC -!- FUNCTION: Probable transcription factor that may act in the sucrose-
CC signaling pathway. {ECO:0000269|PubMed:11292072}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- TISSUE SPECIFICITY: Predominantly expressed in leaves and flowers.
CC {ECO:0000269|PubMed:16055682}.
CC -!- SIMILARITY: Belongs to the HD-ZIP homeobox family. Class I subfamily.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAM63933.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; AF208044; AAF20996.1; -; mRNA.
DR EMBL; AC013289; AAG52541.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE34974.1; -; Genomic_DNA.
DR EMBL; AY057572; AAL09811.1; -; mRNA.
DR EMBL; AY133645; AAM91475.1; -; mRNA.
DR EMBL; AY086888; AAM63933.1; ALT_INIT; mRNA.
DR PIR; H96719; H96719.
DR RefSeq; NP_177136.1; NM_105646.3.
DR AlphaFoldDB; Q8LC03; -.
DR SMR; Q8LC03; -.
DR BioGRID; 28535; 31.
DR IntAct; Q8LC03; 29.
DR STRING; 3702.AT1G69780.1; -.
DR PaxDb; Q8LC03; -.
DR PRIDE; Q8LC03; -.
DR ProteomicsDB; 246823; -.
DR EnsemblPlants; AT1G69780.1; AT1G69780.1; AT1G69780.
DR GeneID; 843314; -.
DR Gramene; AT1G69780.1; AT1G69780.1; AT1G69780.
DR KEGG; ath:AT1G69780; -.
DR Araport; AT1G69780; -.
DR TAIR; locus:2205075; AT1G69780.
DR eggNOG; KOG0483; Eukaryota.
DR HOGENOM; CLU_060842_4_0_1; -.
DR InParanoid; Q8LC03; -.
DR OMA; GCCDLET; -.
DR OrthoDB; 1227444at2759; -.
DR PhylomeDB; Q8LC03; -.
DR PRO; PR:Q8LC03; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q8LC03; baseline and differential.
DR Genevisible; Q8LC03; AT.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IDA:TAIR.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IPI:TAIR.
DR GO; GO:0048826; P:cotyledon morphogenesis; IMP:TAIR.
DR GO; GO:0009965; P:leaf morphogenesis; IMP:TAIR.
DR GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IBA:GO_Central.
DR GO; GO:0080022; P:primary root development; IMP:TAIR.
DR GO; GO:0009744; P:response to sucrose; IMP:TAIR.
DR CDD; cd00086; homeodomain; 1.
DR InterPro; IPR045224; HDZip_class_I_plant.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017970; Homeobox_CS.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR000047; HTH_motif.
DR InterPro; IPR003106; Leu_zip_homeo.
DR PANTHER; PTHR24326; PTHR24326; 1.
DR Pfam; PF02183; HALZ; 1.
DR Pfam; PF00046; Homeodomain; 1.
DR PRINTS; PR00031; HTHREPRESSR.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; SSF46689; 1.
DR PROSITE; PS00027; HOMEOBOX_1; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 2: Evidence at transcript level;
KW DNA-binding; Homeobox; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..294
FT /note="Homeobox-leucine zipper protein ATHB-13"
FT /id="PRO_0000257794"
FT DNA_BIND 82..141
FT /note="Homeobox"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00108"
FT REGION 142..177
FT /note="Leucine-zipper"
FT REGION 181..246
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 181..227
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 154
FT /note="D -> H (in Ref. 5; AAM63933)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 294 AA; 33342 MW; B7384ADCA303B4C0 CRC64;
MSCNNGMSFF PSNFMIQTSY EDDHPHQSPS LAPLLPSCSL PQDLHGFASF LGKRSPMEGC
CDLETGNNMN GEEDYSDDGS QMGEKKRRLN MEQVKTLEKN FELGNKLEPE RKMQLARALG
LQPRQIAIWF QNRRARWKTK QLEKDYDTLK RQFDTLKAEN DLLQTHNQKL QAEIMGLKNR
EQTESINLNK ETEGSCSNRS DNSSDNLRLD ISTAPPSNDS TLTGGHPPPP QTVGRHFFPP
SPATATTTTT TMQFFQNSSS GQSMVKEENS ISNMFCAMDD HSGFWPWLDQ QQYN
