PP300_ARATH
ID PP300_ARATH Reviewed; 502 AA.
AC Q93WC5; Q9SYJ6;
DT 10-FEB-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-DEC-2001, sequence version 1.
DT 25-MAY-2022, entry version 108.
DE RecName: Full=Pentatricopeptide repeat-containing protein At4g01990, mitochondrial;
DE Flags: Precursor;
GN OrderedLocusNames=At4g01990; ORFNames=T7B11.26;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617198; DOI=10.1038/47134;
RA Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B.,
RA Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M.,
RA de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M.,
RA Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D.,
RA Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J.,
RA Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B.,
RA Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J.,
RA Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R.,
RA Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S.,
RA Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J.,
RA Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S.,
RA Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A.,
RA Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M.,
RA Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D.,
RA Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S.,
RA Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R.,
RA Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M.,
RA Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H.,
RA Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N.,
RA Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A.,
RA Martienssen R., McCombie W.R.;
RT "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL Nature 402:769-777(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP GENE FAMILY.
RX PubMed=15269332; DOI=10.1105/tpc.104.022236;
RA Lurin C., Andres C., Aubourg S., Bellaoui M., Bitton F., Bruyere C.,
RA Caboche M., Debast C., Gualberto J., Hoffmann B., Lecharny A., Le Ret M.,
RA Martin-Magniette M.-L., Mireau H., Peeters N., Renou J.-P., Szurek B.,
RA Taconnat L., Small I.;
RT "Genome-wide analysis of Arabidopsis pentatricopeptide repeat proteins
RT reveals their essential role in organelle biogenesis.";
RL Plant Cell 16:2089-2103(2004).
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the PPR family. P subfamily. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAD22661.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC Sequence=CAB80692.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC -!- WEB RESOURCE: Name=Pentatricopeptide repeat proteins;
CC URL="https://ppr.plantenergy.uwa.edu.au";
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DR EMBL; AC007138; AAD22661.1; ALT_INIT; Genomic_DNA.
DR EMBL; AL161493; CAB80692.1; ALT_INIT; Genomic_DNA.
DR EMBL; CP002687; AEE82108.1; -; Genomic_DNA.
DR EMBL; AY039582; AAK62637.1; -; mRNA.
DR EMBL; AY059165; AAL15390.1; -; mRNA.
DR PIR; E85025; E85025.
DR RefSeq; NP_567220.1; NM_116430.2.
DR AlphaFoldDB; Q93WC5; -.
DR SMR; Q93WC5; -.
DR BioGRID; 13461; 1.
DR IntAct; Q93WC5; 1.
DR STRING; 3702.AT4G01990.1; -.
DR iPTMnet; Q93WC5; -.
DR PaxDb; Q93WC5; -.
DR PRIDE; Q93WC5; -.
DR ProteomicsDB; 249211; -.
DR EnsemblPlants; AT4G01990.1; AT4G01990.1; AT4G01990.
DR GeneID; 828172; -.
DR Gramene; AT4G01990.1; AT4G01990.1; AT4G01990.
DR KEGG; ath:AT4G01990; -.
DR Araport; AT4G01990; -.
DR TAIR; locus:2141360; AT4G01990.
DR eggNOG; KOG4197; Eukaryota.
DR HOGENOM; CLU_019802_3_0_1; -.
DR InParanoid; Q93WC5; -.
DR OMA; TYCILIE; -.
DR OrthoDB; 1344243at2759; -.
DR PhylomeDB; Q93WC5; -.
DR PRO; PR:Q93WC5; -.
DR Proteomes; UP000006548; Chromosome 4.
DR ExpressionAtlas; Q93WC5; baseline and differential.
DR Genevisible; Q93WC5; AT.
DR GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR GO; GO:0003729; F:mRNA binding; IDA:TAIR.
DR Gene3D; 1.25.40.10; -; 3.
DR InterPro; IPR002885; Pentatricopeptide_repeat.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR Pfam; PF01535; PPR; 4.
DR SUPFAM; SSF48452; SSF48452; 2.
DR TIGRFAMs; TIGR00756; PPR; 1.
PE 2: Evidence at transcript level;
KW Mitochondrion; Reference proteome; Repeat; Transit peptide.
FT TRANSIT 1..13
FT /note="Mitochondrion"
FT /evidence="ECO:0000255"
FT CHAIN 14..502
FT /note="Pentatricopeptide repeat-containing protein
FT At4g01990, mitochondrial"
FT /id="PRO_0000363418"
FT REPEAT 139..173
FT /note="PPR 1"
FT REPEAT 174..208
FT /note="PPR 2"
FT REPEAT 209..243
FT /note="PPR 3"
FT REPEAT 245..275
FT /note="PPR 4"
FT REPEAT 280..310
FT /note="PPR 5"
FT REPEAT 315..345
FT /note="PPR 6"
FT REPEAT 350..381
FT /note="PPR 7"
SQ SEQUENCE 502 AA; 56942 MW; 340F53F4223F6F8B CRC64;
MMHSVSRLAR RFCATLATAT AEISGEAAAS VPTKAKKHRS IYKKLSSLGT RGGGKMEETL
NQFVMEGVPV KKHDLIRYAK DLRKFRQPQR ALEIFEWMER KEIAFTGSDH AIRLNLIAKS
KGLEAAETYF NSLDDSIKNQ STYGSLLNCY CVEKEEVKAK AHFENMVDLN HVSNSLPFNN
LMAMYMGLGQ PEKVPALVVA MKEKSITPCD ITYSMWIQSC GSLKDLDGVE KVLDEMKAEG
EGIFSWNTFA NLAAIYIKVG LYGKAEEALK SLENNMNPDV RDCYHFLINL YTGIANASEV
YRVWDLLKKR YPNVNNSSYL TMLRALSKLD DIDGVKKVFA EWESTCWTYD MRMANVAISS
YLKQNMYEEA EAVFNGAMKK CKGQFSKARQ LLMMHLLKND QADLALKHFE AAVLDQDKNW
TWSSELISSF FLHFEEAKDV DGAEEFCKTL TKWSPLSSET YTLLMKTYLA AGKACPDMKK
RLEEQGILVD EEQECLLSKI CP
