ID   PP301_ARATH             Reviewed;         781 AA.
AC   Q9SY02;
DT   10-FEB-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   03-AUG-2022, entry version 123.
DE   RecName: Full=Pentatricopeptide repeat-containing protein At4g02750;
GN   Name=PCMP-H24; OrderedLocusNames=At4g02750; ORFNames=T5J8.5;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10617198; DOI=10.1038/47134;
RA   Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA   Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B.,
RA   Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M.,
RA   de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M.,
RA   Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D.,
RA   Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J.,
RA   Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B.,
RA   Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J.,
RA   Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R.,
RA   Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA   Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA   Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S.,
RA   Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA   Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J.,
RA   Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S.,
RA   Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A.,
RA   Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M.,
RA   Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M.,
RA   Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D.,
RA   Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA   Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S.,
RA   Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R.,
RA   Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA   Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA   Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA   Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA   Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA   de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA   Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M.,
RA   Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA   Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA   Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA   Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA   Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H.,
RA   Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA   Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA   Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA   O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N.,
RA   Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A.,
RA   Martienssen R., McCombie W.R.;
RT   "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL   Nature 402:769-777(1999).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   GENE FAMILY.
RX   PubMed=10809006; DOI=10.1023/a:1006352315928;
RA   Aubourg S., Boudet N., Kreis M., Lecharny A.;
RT   "In Arabidopsis thaliana, 1% of the genome codes for a novel protein family
RT   unique to plants.";
RL   Plant Mol. Biol. 42:603-613(2000).
RN   [4]
RP   GENE FAMILY.
RX   PubMed=15269332; DOI=10.1105/tpc.104.022236;
RA   Lurin C., Andres C., Aubourg S., Bellaoui M., Bitton F., Bruyere C.,
RA   Caboche M., Debast C., Gualberto J., Hoffmann B., Lecharny A., Le Ret M.,
RA   Martin-Magniette M.-L., Mireau H., Peeters N., Renou J.-P., Szurek B.,
RA   Taconnat L., Small I.;
RT   "Genome-wide analysis of Arabidopsis pentatricopeptide repeat proteins
RT   reveals their essential role in organelle biogenesis.";
RL   Plant Cell 16:2089-2103(2004).
CC   -!- SIMILARITY: Belongs to the PPR family. PCMP-H subfamily. {ECO:0000305}.
CC   -!- WEB RESOURCE: Name=Pentatricopeptide repeat proteins;
CC       URL="https://ppr.plantenergy.uwa.edu.au";
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DR   EMBL; AC004044; AAD15348.1; -; Genomic_DNA.
DR   EMBL; AL161495; CAB77760.1; -; Genomic_DNA.
DR   EMBL; CP002687; AEE82224.1; -; Genomic_DNA.
DR   PIR; A85035; A85035.
DR   RefSeq; NP_192184.1; NM_116509.2.
DR   AlphaFoldDB; Q9SY02; -.
DR   SMR; Q9SY02; -.
DR   STRING; 3702.AT4G02750.1; -.
DR   PaxDb; Q9SY02; -.
DR   PRIDE; Q9SY02; -.
DR   ProteomicsDB; 249212; -.
DR   EnsemblPlants; AT4G02750.1; AT4G02750.1; AT4G02750.
DR   GeneID; 828187; -.
DR   Gramene; AT4G02750.1; AT4G02750.1; AT4G02750.
DR   KEGG; ath:AT4G02750; -.
DR   Araport; AT4G02750; -.
DR   TAIR; locus:2140235; AT4G02750.
DR   eggNOG; KOG4197; Eukaryota.
DR   HOGENOM; CLU_002706_30_2_1; -.
DR   InParanoid; Q9SY02; -.
DR   OMA; FEAMPCR; -.
DR   OrthoDB; 1344243at2759; -.
DR   PhylomeDB; Q9SY02; -.
DR   PRO; PR:Q9SY02; -.
DR   Proteomes; UP000006548; Chromosome 4.
DR   ExpressionAtlas; Q9SY02; baseline and differential.
DR   Genevisible; Q9SY02; AT.
DR   GO; GO:0043231; C:intracellular membrane-bounded organelle; IBA:GO_Central.
DR   GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0140547; P:acquisition of seed longevity; IMP:TAIR.
DR   GO; GO:0009451; P:RNA modification; IBA:GO_Central.
DR   GO; GO:0010214; P:seed coat development; IMP:TAIR.
DR   Gene3D; 1.25.40.10; -; 7.
DR   InterPro; IPR032867; DYW_dom.
DR   InterPro; IPR002885; Pentatricopeptide_repeat.
DR   InterPro; IPR045215; PPR_prot_plant.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   PANTHER; PTHR24015; PTHR24015; 2.
DR   Pfam; PF14432; DYW_deaminase; 1.
DR   Pfam; PF01535; PPR; 10.
DR   Pfam; PF12854; PPR_1; 1.
DR   Pfam; PF13041; PPR_2; 1.
DR   SUPFAM; SSF48452; SSF48452; 2.
DR   TIGRFAMs; TIGR00756; PPR; 13.
DR   PROSITE; PS51375; PPR; 17.
PE   3: Inferred from homology;
KW   Reference proteome; Repeat.
FT   CHAIN           1..781
FT                   /note="Pentatricopeptide repeat-containing protein
FT                   At4g02750"
FT                   /id="PRO_0000363419"
FT   REPEAT          63..93
FT                   /note="PPR 1"
FT   REPEAT          94..128
FT                   /note="PPR 2"
FT   REPEAT          129..155
FT                   /note="PPR 3"
FT   REPEAT          156..190
FT                   /note="PPR 4"
FT   REPEAT          191..217
FT                   /note="PPR 5"
FT   REPEAT          218..248
FT                   /note="PPR 6"
FT   REPEAT          249..279
FT                   /note="PPR 7"
FT   REPEAT          280..314
FT                   /note="PPR 8"
FT   REPEAT          315..341
FT                   /note="PPR 9"
FT   REPEAT          342..376
FT                   /note="PPR 10"
FT   REPEAT          377..407
FT                   /note="PPR 11"
FT   REPEAT          408..442
FT                   /note="PPR 12"
FT   REPEAT          443..473
FT                   /note="PPR 13"
FT   REPEAT          474..508
FT                   /note="PPR 14"
FT   REPEAT          509..544
FT                   /note="PPR 15"
FT   REPEAT          545..575
FT                   /note="PPR 16"
FT   REGION          580..655
FT                   /note="Type E motif"
FT   REGION          656..686
FT                   /note="Type E(+) motif"
FT   REGION          687..781
FT                   /note="Type DYW motif"
SQ   SEQUENCE   781 AA;  89037 MW;  6E8DE8B6C425E20A CRC64;
     MEINKFRALS RRAQQLHYTS LNGLKRRCNN AHGAANFHSL KRATQTQIQK SQTKPLLKCG
     DSDIKEWNVA ISSYMRTGRC NEALRVFKRM PRWSSVSYNG MISGYLRNGE FELARKLFDE
     MPERDLVSWN VMIKGYVRNR NLGKARELFE IMPERDVCSW NTMLSGYAQN GCVDDARSVF
     DRMPEKNDVS WNALLSAYVQ NSKMEEACML FKSRENWALV SWNCLLGGFV KKKKIVEARQ
     FFDSMNVRDV VSWNTIITGY AQSGKIDEAR QLFDESPVQD VFTWTAMVSG YIQNRMVEEA
     RELFDKMPER NEVSWNAMLA GYVQGERMEM AKELFDVMPC RNVSTWNTMI TGYAQCGKIS
     EAKNLFDKMP KRDPVSWAAM IAGYSQSGHS FEALRLFVQM EREGGRLNRS SFSSALSTCA
     DVVALELGKQ LHGRLVKGGY ETGCFVGNAL LLMYCKCGSI EEANDLFKEM AGKDIVSWNT
     MIAGYSRHGF GEVALRFFES MKREGLKPDD ATMVAVLSAC SHTGLVDKGR QYFYTMTQDY
     GVMPNSQHYA CMVDLLGRAG LLEDAHNLMK NMPFEPDAAI WGTLLGASRV HGNTELAETA
     ADKIFAMEPE NSGMYVLLSN LYASSGRWGD VGKLRVRMRD KGVKKVPGYS WIEIQNKTHT
     FSVGDEFHPE KDEIFAFLEE LDLRMKKAGY VSKTSVVLHD VEEEEKERMV RYHSERLAVA
     YGIMRVSSGR PIRVIKNLRV CEDCHNAIKY MARITGRLII LRDNNRFHHF KDGSCSCGDY
     W