PP304_ARATH
ID PP304_ARATH Reviewed; 821 AA.
AC Q6NQ81; Q9M0Z7; Q9ZS94;
DT 10-FEB-2009, integrated into UniProtKB/Swiss-Prot.
DT 10-FEB-2009, sequence version 2.
DT 25-MAY-2022, entry version 101.
DE RecName: Full=Pentatricopeptide repeat-containing protein At4g04790, mitochondrial;
DE Flags: Precursor;
GN OrderedLocusNames=At4g04790; ORFNames=T4B21.17;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617198; DOI=10.1038/47134;
RA Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B.,
RA Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M.,
RA de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M.,
RA Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D.,
RA Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J.,
RA Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B.,
RA Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J.,
RA Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R.,
RA Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S.,
RA Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J.,
RA Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S.,
RA Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A.,
RA Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M.,
RA Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D.,
RA Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S.,
RA Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R.,
RA Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M.,
RA Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H.,
RA Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N.,
RA Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A.,
RA Martienssen R., McCombie W.R.;
RT "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL Nature 402:769-777(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP GENE FAMILY.
RX PubMed=15269332; DOI=10.1105/tpc.104.022236;
RA Lurin C., Andres C., Aubourg S., Bellaoui M., Bitton F., Bruyere C.,
RA Caboche M., Debast C., Gualberto J., Hoffmann B., Lecharny A., Le Ret M.,
RA Martin-Magniette M.-L., Mireau H., Peeters N., Renou J.-P., Szurek B.,
RA Taconnat L., Small I.;
RT "Genome-wide analysis of Arabidopsis pentatricopeptide repeat proteins
RT reveals their essential role in organelle biogenesis.";
RL Plant Cell 16:2089-2103(2004).
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the PPR family. P subfamily. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAD03456.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=CAB80844.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC -!- WEB RESOURCE: Name=Pentatricopeptide repeat proteins;
CC URL="https://ppr.plantenergy.uwa.edu.au";
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DR EMBL; AF118223; AAD03456.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AL161501; CAB80844.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002687; AEE82426.1; -; Genomic_DNA.
DR EMBL; BT010578; AAQ82839.1; -; mRNA.
DR EMBL; AK221389; BAD94316.1; -; mRNA.
DR PIR; C85060; C85060.
DR RefSeq; NP_192388.3; NM_116717.4.
DR AlphaFoldDB; Q6NQ81; -.
DR SMR; Q6NQ81; -.
DR PaxDb; Q6NQ81; -.
DR PRIDE; Q6NQ81; -.
DR ProteomicsDB; 249215; -.
DR EnsemblPlants; AT4G04790.1; AT4G04790.1; AT4G04790.
DR GeneID; 825816; -.
DR Gramene; AT4G04790.1; AT4G04790.1; AT4G04790.
DR KEGG; ath:AT4G04790; -.
DR Araport; AT4G04790; -.
DR TAIR; locus:2138882; AT4G04790.
DR eggNOG; KOG4197; Eukaryota.
DR HOGENOM; CLU_013098_0_0_1; -.
DR InParanoid; Q6NQ81; -.
DR OrthoDB; 1344243at2759; -.
DR PhylomeDB; Q6NQ81; -.
DR PRO; PR:Q6NQ81; -.
DR Proteomes; UP000006548; Chromosome 4.
DR ExpressionAtlas; Q6NQ81; baseline and differential.
DR Genevisible; Q6NQ81; AT.
DR GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR Gene3D; 1.25.40.10; -; 2.
DR InterPro; IPR002885; Pentatricopeptide_repeat.
DR InterPro; IPR033443; PPR_long.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR Pfam; PF01535; PPR; 3.
DR Pfam; PF17177; PPR_long; 1.
DR TIGRFAMs; TIGR00756; PPR; 2.
DR PROSITE; PS51375; PPR; 7.
PE 2: Evidence at transcript level;
KW Mitochondrion; Reference proteome; Repeat; Transit peptide.
FT TRANSIT 1..74
FT /note="Mitochondrion"
FT /evidence="ECO:0000255"
FT CHAIN 75..821
FT /note="Pentatricopeptide repeat-containing protein
FT At4g04790, mitochondrial"
FT /id="PRO_0000363422"
FT REPEAT 372..406
FT /note="PPR 1"
FT REPEAT 407..441
FT /note="PPR 2"
FT REPEAT 442..476
FT /note="PPR 3"
FT REPEAT 477..511
FT /note="PPR 4"
FT REPEAT 512..542
FT /note="PPR 5"
FT REPEAT 544..574
FT /note="PPR 6"
FT REPEAT 578..612
FT /note="PPR 7"
FT REGION 801..821
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 807..821
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 30
FT /note="G -> S (in Ref. 3; BAD94316 and 4; AAQ82839)"
FT /evidence="ECO:0000305"
FT CONFLICT 116
FT /note="N -> S (in Ref. 3; BAD94316 and 4; AAQ82839)"
FT /evidence="ECO:0000305"
FT CONFLICT 294
FT /note="D -> G (in Ref. 3; BAD94316 and 4; AAQ82839)"
FT /evidence="ECO:0000305"
FT CONFLICT 309
FT /note="E -> G (in Ref. 3; BAD94316 and 4; AAQ82839)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 821 AA; 92836 MW; C2E2A9B5739EEE72 CRC64;
MVVSKVNKSL LSSVFKSRIR PTGESSIASG NKDIAGTSQA VKDLLSSKNS SSDLEEASLQ
DRVSKLLHVT TSDKSSLEKN LFLKIPSFTT KIPYDISLRT KELSRERKER RVYKQNGLSR
RFAKIFRDSA QKLGTEAMFG AFDRVAKEMS VTEYNAMIGV YLEHAEKSND LDYALGHIEK
AFELLKSMRD RGFLIEERVY GPLLGYLIGM DMVDEFHSFK DVIREASPGS VERLGYYEML
LWIHLGDGEK IEELCSTIDG DNGESLSVLQ ENYLLALCKK DQKYHLERLL EIVDITKVRS
SDLLANIFEY LGRFSLDSVA SRFLWELRES DEGVKNVSDL ISIYSTCTPN PTVEDTILKF
NKMHEELDVM PSSTSYEKLV KYSCDSNEVV TALDVVEKMG EAGLMISADI LHSLLHAIDE
VLEFDLVRRI HSIMCTKSVK PNTENFRSII RLCTRIKDFE GAYNMLGNLK NFNLEPNSSM
FNCILAGYFR EKNVSSALMV VKQMKEAGVK PDSITFGYLI NNCTQEDAIT KYYEEMKQAG
VQATKRIYMS LIDAYAASGK FEKAKQVLVD PDVPAINQNE LKSVLISALA SRGKWADALH
IYEEMRKAEC HVDPKSIISL IEYSDSKGEL STLVQLADDL QDDTSWIDGF FRMILFAVRN
KKSSDIVDLL KRNKVRLLKK GIPVEAHFDE VFWAIAETEP SKVHLGMDLL RFMKDELGFV
PSRKCLDFLL HACVNAKDLE HGLLVWKEYQ SAAFPCNVLS FLRMYQVLLA AGDSEGAKAL
VSKIPKDDKD VQHIIEESQS AFSQAPNKKK PKKKMIVLST K
