PP316_ARATH
ID PP316_ARATH Reviewed; 656 AA.
AC Q9M4P3; F4JMM2;
DT 10-FEB-2009, integrated into UniProtKB/Swiss-Prot.
DT 16-NOV-2011, sequence version 3.
DT 25-MAY-2022, entry version 107.
DE RecName: Full=Pentatricopeptide repeat-containing protein At4g16835, mitochondrial;
DE AltName: Full=Protein DYW10;
DE Flags: Precursor;
GN Name=DYW10; Synonyms=PCMP-H10; OrderedLocusNames=At4g16835;
GN ORFNames=FCAALL.441;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=9461215; DOI=10.1038/35140;
RA Bevan M., Bancroft I., Bent E., Love K., Goodman H.M., Dean C.,
RA Bergkamp R., Dirkse W., van Staveren M., Stiekema W., Drost L., Ridley P.,
RA Hudson S.-A., Patel K., Murphy G., Piffanelli P., Wedler H., Wedler E.,
RA Wambutt R., Weitzenegger T., Pohl T., Terryn N., Gielen J., Villarroel R.,
RA De Clercq R., van Montagu M., Lecharny A., Aubourg S., Gy I., Kreis M.,
RA Lao N., Kavanagh T., Hempel S., Kotter P., Entian K.-D., Rieger M.,
RA Schaefer M., Funk B., Mueller-Auer S., Silvey M., James R., Monfort A.,
RA Pons A., Puigdomenech P., Douka A., Voukelatou E., Milioni D.,
RA Hatzopoulos P., Piravandi E., Obermaier B., Hilbert H., Duesterhoeft A.,
RA Moores T., Jones J.D.G., Eneva T., Palme K., Benes V., Rechmann S.,
RA Ansorge W., Cooke R., Berger C., Delseny M., Voet M., Volckaert G.,
RA Mewes H.-W., Klosterman S., Schueller C., Chalwatzis N.;
RT "Analysis of 1.9 Mb of contiguous sequence from chromosome 4 of Arabidopsis
RT thaliana.";
RL Nature 391:485-488(1998).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617198; DOI=10.1038/47134;
RA Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B.,
RA Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M.,
RA de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M.,
RA Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D.,
RA Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J.,
RA Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B.,
RA Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J.,
RA Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R.,
RA Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S.,
RA Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J.,
RA Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S.,
RA Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A.,
RA Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M.,
RA Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D.,
RA Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S.,
RA Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R.,
RA Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M.,
RA Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H.,
RA Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N.,
RA Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A.,
RA Martienssen R., McCombie W.R.;
RT "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL Nature 402:769-777(1999).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 552-656, AND GENE FAMILY.
RX PubMed=10809006; DOI=10.1023/a:1006352315928;
RA Aubourg S., Boudet N., Kreis M., Lecharny A.;
RT "In Arabidopsis thaliana, 1% of the genome codes for a novel protein family
RT unique to plants.";
RL Plant Mol. Biol. 42:603-613(2000).
RN [5]
RP GENE FAMILY.
RX PubMed=15269332; DOI=10.1105/tpc.104.022236;
RA Lurin C., Andres C., Aubourg S., Bellaoui M., Bitton F., Bruyere C.,
RA Caboche M., Debast C., Gualberto J., Hoffmann B., Lecharny A., Le Ret M.,
RA Martin-Magniette M.-L., Mireau H., Peeters N., Renou J.-P., Szurek B.,
RA Taconnat L., Small I.;
RT "Genome-wide analysis of Arabidopsis pentatricopeptide repeat proteins
RT reveals their essential role in organelle biogenesis.";
RL Plant Cell 16:2089-2103(2004).
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the PPR family. PCMP-H subfamily. {ECO:0000305}.
CC -!- WEB RESOURCE: Name=Pentatricopeptide repeat proteins;
CC URL="https://ppr.plantenergy.uwa.edu.au";
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; Z97342; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AL161545; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CP002687; AEE83812.1; -; Genomic_DNA.
DR EMBL; AJ006043; CAA06832.1; -; mRNA.
DR PIR; T52644; T52644.
DR RefSeq; NP_680717.2; NM_148351.3.
DR AlphaFoldDB; Q9M4P3; -.
DR SMR; Q9M4P3; -.
DR iPTMnet; Q9M4P3; -.
DR PaxDb; Q9M4P3; -.
DR PRIDE; Q9M4P3; -.
DR ProteomicsDB; 248983; -.
DR EnsemblPlants; AT4G16835.1; AT4G16835.1; AT4G16835.
DR GeneID; 827390; -.
DR Gramene; AT4G16835.1; AT4G16835.1; AT4G16835.
DR KEGG; ath:AT4G16835; -.
DR Araport; AT4G16835; -.
DR TAIR; locus:504955435; AT4G16835.
DR eggNOG; KOG4197; Eukaryota.
DR HOGENOM; CLU_002706_37_8_1; -.
DR InParanoid; Q9M4P3; -.
DR OMA; MPFKPHP; -.
DR OrthoDB; 1344243at2759; -.
DR PRO; PR:Q9M4P3; -.
DR Proteomes; UP000006548; Chromosome 4.
DR ExpressionAtlas; Q9M4P3; baseline and differential.
DR GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR Gene3D; 1.25.40.10; -; 4.
DR InterPro; IPR032867; DYW_dom.
DR InterPro; IPR002885; Pentatricopeptide_repeat.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR Pfam; PF14432; DYW_deaminase; 1.
DR Pfam; PF01535; PPR; 6.
DR Pfam; PF12854; PPR_1; 1.
DR Pfam; PF13041; PPR_2; 2.
DR SUPFAM; SSF48452; SSF48452; 1.
DR TIGRFAMs; TIGR00756; PPR; 9.
DR PROSITE; PS51375; PPR; 11.
PE 2: Evidence at transcript level;
KW Mitochondrion; Reference proteome; Repeat; Transit peptide.
FT TRANSIT 1..71
FT /note="Mitochondrion"
FT /evidence="ECO:0000255"
FT CHAIN 72..656
FT /note="Pentatricopeptide repeat-containing protein
FT At4g16835, mitochondrial"
FT /id="PRO_0000363434"
FT REPEAT 60..94
FT /note="PPR 1"
FT REPEAT 95..122
FT /note="PPR 2"
FT REPEAT 123..153
FT /note="PPR 3"
FT REPEAT 154..188
FT /note="PPR 4"
FT REPEAT 189..215
FT /note="PPR 5"
FT REPEAT 216..246
FT /note="PPR 6"
FT REPEAT 248..282
FT /note="PPR 7"
FT REPEAT 283..317
FT /note="PPR 8"
FT REPEAT 318..348
FT /note="PPR 9"
FT REPEAT 349..383
FT /note="PPR 10"
FT REPEAT 384..414
FT /note="PPR 11"
FT REPEAT 420..454
FT /note="PPR 12"
FT REGION 455..530
FT /note="Type E motif"
FT REGION 531..561
FT /note="Type E(+) motif"
FT REGION 562..656
FT /note="Type DYW motif"
FT CONFLICT 603
FT /note="Q -> E (in Ref. 4; CAA06832)"
FT /evidence="ECO:0000305"
FT CONFLICT 606
FT /note="Q -> P (in Ref. 4; CAA06832)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 656 AA; 74819 MW; 65A82760EBD768AD CRC64;
MLSRFNIHQP FKRCKFRFFL RSIGNPDTIL VESCSSSSCS SPEPSLVRSD YLTKPSDQDQ
IFPLNKIIAR CVRSGDIDGA LRVFHGMRAK NTITWNSLLI GISKDPSRMM EAHQLFDEIP
EPDTFSYNIM LSCYVRNVNF EKAQSFFDRM PFKDAASWNT MITGYARRGE MEKARELFYS
MMEKNEVSWN AMISGYIECG DLEKASHFFK VAPVRGVVAW TAMITGYMKA KKVELAEAMF
KDMTVNKNLV TWNAMISGYV ENSRPEDGLK LFRAMLEEGI RPNSSGLSSA LLGCSELSAL
QLGRQIHQIV SKSTLCNDVT ALTSLISMYC KCGELGDAWK LFEVMKKKDV VAWNAMISGY
AQHGNADKAL CLFREMIDNK IRPDWITFVA VLLACNHAGL VNIGMAYFES MVRDYKVEPQ
PDHYTCMVDL LGRAGKLEEA LKLIRSMPFR PHAAVFGTLL GACRVHKNVE LAEFAAEKLL
QLNSQNAAGY VQLANIYASK NRWEDVARVR KRMKESNVVK VPGYSWIEIR NKVHHFRSSD
RIHPELDSIH KKLKELEKKM KLAGYKPELE FALHNVEEEQ KEKLLLWHSE KLAVAFGCIK
LPQGSQIQVF KNLRICGDCH KAIKFISEIE KREIIVRDTT RFHHFKDGSC SCGDYW
