ATB21_ARATH
ID ATB21_ARATH Reviewed; 220 AA.
AC Q9ZU70; B2GVN1;
DT 31-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1999, sequence version 1.
DT 25-MAY-2022, entry version 148.
DE RecName: Full=Homeobox-leucine zipper protein ATHB-21;
DE AltName: Full=HD-ZIP protein ATHB-21;
DE AltName: Full=Homeodomain transcription factor ATHB-21;
GN Name=ATHB-21; OrderedLocusNames=At2g18550; ORFNames=F24H14.10;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA De Los Reyes C., Quan R., Chen H., Bautista V.R., Kim C.J., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP GENE FAMILY, TISSUE SPECIFICITY, AND INDUCTION.
RX PubMed=16055682; DOI=10.1104/pp.105.063461;
RA Henriksson E., Olsson A.S.B., Johannesson H., Johansson H., Hanson J.,
RA Engstroem P., Soederman E.;
RT "Homeodomain leucine zipper class I genes in Arabidopsis. Expression
RT patterns and phylogenetic relationships.";
RL Plant Physiol. 139:509-518(2005).
CC -!- FUNCTION: Probable transcription factor. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- TISSUE SPECIFICITY: Widely expressed. {ECO:0000269|PubMed:16055682}.
CC -!- INDUCTION: By abscisic acid (ABA) and by salt stress.
CC {ECO:0000269|PubMed:16055682}.
CC -!- SIMILARITY: Belongs to the HD-ZIP homeobox family. Class I subfamily.
CC {ECO:0000305}.
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DR EMBL; AC006135; AAD12212.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC06780.1; -; Genomic_DNA.
DR EMBL; BT031362; ACB88824.1; -; mRNA.
DR PIR; F84565; F84565.
DR RefSeq; NP_179445.1; NM_127411.2.
DR AlphaFoldDB; Q9ZU70; -.
DR SMR; Q9ZU70; -.
DR BioGRID; 1727; 6.
DR STRING; 3702.AT2G18550.1; -.
DR PaxDb; Q9ZU70; -.
DR PRIDE; Q9ZU70; -.
DR ProteomicsDB; 246533; -.
DR EnsemblPlants; AT2G18550.1; AT2G18550.1; AT2G18550.
DR GeneID; 816370; -.
DR Gramene; AT2G18550.1; AT2G18550.1; AT2G18550.
DR KEGG; ath:AT2G18550; -.
DR Araport; AT2G18550; -.
DR TAIR; locus:2046263; AT2G18550.
DR eggNOG; KOG0483; Eukaryota.
DR HOGENOM; CLU_100008_1_0_1; -.
DR InParanoid; Q9ZU70; -.
DR OMA; DYDIGFD; -.
DR OrthoDB; 1260515at2759; -.
DR PhylomeDB; Q9ZU70; -.
DR PRO; PR:Q9ZU70; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q9ZU70; baseline and differential.
DR Genevisible; Q9ZU70; AT.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IBA:GO_Central.
DR CDD; cd00086; homeodomain; 1.
DR InterPro; IPR045224; HDZip_class_I_plant.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017970; Homeobox_CS.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR000047; HTH_motif.
DR PANTHER; PTHR24326; PTHR24326; 1.
DR Pfam; PF00046; Homeodomain; 1.
DR PRINTS; PR00031; HTHREPRESSR.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; SSF46689; 1.
DR PROSITE; PS00027; HOMEOBOX_1; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 2: Evidence at transcript level;
KW DNA-binding; Homeobox; Nucleus; Reference proteome; Stress response;
KW Transcription; Transcription regulation.
FT CHAIN 1..220
FT /note="Homeobox-leucine zipper protein ATHB-21"
FT /id="PRO_0000257798"
FT DNA_BIND 58..117
FT /note="Homeobox"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00108"
FT REGION 26..48
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 118..146
FT /note="Leucine-zipper"
SQ SEQUENCE 220 AA; 25701 MW; 7C421B8EA75EBCB3 CRC64;
MNNQNVDDHN LLLISQLYPN VYTPLVPQQG GEAKPTRRRK RKSKSVVVAE EGENEGNGWF
RKRKLSDEQV RMLEISFEDD HKLESERKDR LASELGLDPR QVAVWFQNRR ARWKNKRVED
EYTKLKNAYE TTVVEKCRLD SEVIHLKEQL YEAEREIQRL AKRVEGTLSN SPISSSVTIE
ANHTTPFFGD YDIGFDGEAD ENLLYSPDYI DGLDWMSQFM
