PP323_ARATH
ID PP323_ARATH Reviewed; 654 AA.
AC P0C8Q2; O49677;
DT 10-FEB-2009, integrated into UniProtKB/Swiss-Prot.
DT 10-FEB-2009, sequence version 1.
DT 03-AUG-2022, entry version 74.
DE RecName: Full=Pentatricopeptide repeat-containing protein At4g19191, mitochondrial;
DE Flags: Precursor;
GN Name=PCMP-E1; OrderedLocusNames=At4g19191; ORFNames=T18B16.160;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617198; DOI=10.1038/47134;
RA Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B.,
RA Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M.,
RA de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M.,
RA Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D.,
RA Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J.,
RA Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B.,
RA Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J.,
RA Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R.,
RA Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S.,
RA Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J.,
RA Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S.,
RA Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A.,
RA Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M.,
RA Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D.,
RA Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S.,
RA Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R.,
RA Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M.,
RA Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H.,
RA Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N.,
RA Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A.,
RA Martienssen R., McCombie W.R.;
RT "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL Nature 402:769-777(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP GENE FAMILY.
RX PubMed=10809006; DOI=10.1023/a:1006352315928;
RA Aubourg S., Boudet N., Kreis M., Lecharny A.;
RT "In Arabidopsis thaliana, 1% of the genome codes for a novel protein family
RT unique to plants.";
RL Plant Mol. Biol. 42:603-613(2000).
RN [4]
RP GENE FAMILY.
RX PubMed=15269332; DOI=10.1105/tpc.104.022236;
RA Lurin C., Andres C., Aubourg S., Bellaoui M., Bitton F., Bruyere C.,
RA Caboche M., Debast C., Gualberto J., Hoffmann B., Lecharny A., Le Ret M.,
RA Martin-Magniette M.-L., Mireau H., Peeters N., Renou J.-P., Szurek B.,
RA Taconnat L., Small I.;
RT "Genome-wide analysis of Arabidopsis pentatricopeptide repeat proteins
RT reveals their essential role in organelle biogenesis.";
RL Plant Cell 16:2089-2103(2004).
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the PPR family. PCMP-E subfamily. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAA16708.1; Type=Erroneous gene model prediction; Note=The predicted gene has been split into 2 genes: At4g19190 and At4g19191.; Evidence={ECO:0000305};
CC Sequence=CAB78921.1; Type=Erroneous gene model prediction; Note=The predicted gene has been split into 2 genes: At4g19190 and At4g19191.; Evidence={ECO:0000305};
CC -!- WEB RESOURCE: Name=Pentatricopeptide repeat proteins;
CC URL="https://ppr.plantenergy.uwa.edu.au";
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DR EMBL; AL021687; CAA16708.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AL161550; CAB78921.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002687; AEE84158.1; -; Genomic_DNA.
DR PIR; T04440; T04440.
DR RefSeq; NP_001119013.1; NM_001125541.1.
DR AlphaFoldDB; P0C8Q2; -.
DR SMR; P0C8Q2; -.
DR STRING; 3702.AT4G19191.1; -.
DR PaxDb; P0C8Q2; -.
DR PRIDE; P0C8Q2; -.
DR EnsemblPlants; AT4G19191.1; AT4G19191.1; AT4G19191.
DR GeneID; 6240220; -.
DR Gramene; AT4G19191.1; AT4G19191.1; AT4G19191.
DR KEGG; ath:AT4G19191; -.
DR Araport; AT4G19191; -.
DR TAIR; locus:4515103421; AT4G19191.
DR eggNOG; KOG3794; Eukaryota.
DR eggNOG; KOG4197; Eukaryota.
DR HOGENOM; CLU_002706_15_10_1; -.
DR InParanoid; P0C8Q2; -.
DR OMA; LFDCMSD; -.
DR OrthoDB; 1344243at2759; -.
DR PhylomeDB; P0C8Q2; -.
DR PRO; PR:P0C8Q2; -.
DR Proteomes; UP000006548; Chromosome 4.
DR ExpressionAtlas; P0C8Q2; baseline and differential.
DR Genevisible; P0C8Q2; AT.
DR GO; GO:0043231; C:intracellular membrane-bounded organelle; IBA:GO_Central.
DR GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR GO; GO:0009451; P:RNA modification; IBA:GO_Central.
DR Gene3D; 1.25.40.10; -; 4.
DR InterPro; IPR002885; Pentatricopeptide_repeat.
DR InterPro; IPR045215; PPR_prot_plant.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR PANTHER; PTHR24015; PTHR24015; 1.
DR Pfam; PF01535; PPR; 4.
DR Pfam; PF13041; PPR_2; 3.
DR TIGRFAMs; TIGR00756; PPR; 6.
DR PROSITE; PS51375; PPR; 13.
PE 2: Evidence at transcript level;
KW Mitochondrion; Reference proteome; Repeat; Transit peptide.
FT TRANSIT 1..65
FT /note="Mitochondrion"
FT /evidence="ECO:0000255"
FT CHAIN 66..654
FT /note="Pentatricopeptide repeat-containing protein
FT At4g19191, mitochondrial"
FT /id="PRO_0000363440"
FT REPEAT 86..116
FT /note="PPR 1"
FT REPEAT 117..151
FT /note="PPR 2"
FT REPEAT 152..186
FT /note="PPR 3"
FT REPEAT 187..217
FT /note="PPR 4"
FT REPEAT 220..254
FT /note="PPR 5"
FT REPEAT 255..289
FT /note="PPR 6"
FT REPEAT 290..320
FT /note="PPR 7"
FT REPEAT 321..355
FT /note="PPR 8"
FT REPEAT 356..390
FT /note="PPR 9"
FT REPEAT 392..422
FT /note="PPR 10"
FT REPEAT 423..457
FT /note="PPR 11"
FT REPEAT 458..488
FT /note="PPR 12"
FT REPEAT 494..524
FT /note="PPR 13"
FT REGION 529..604
FT /note="Type E motif"
FT REGION 605..635
FT /note="Type E(+) motif"
SQ SEQUENCE 654 AA; 73409 MW; 6191030F4EAD6170 CRC64;
MSLIHRRLYR ISGLSSVNAW NLQIREAVNR NDPVESLLLF REMKRGGFEP NNFTFPFVAK
ACARLADVGC CEMVHAHLIK SPFWSDVFVG TATVDMFVKC NSVDYAAKVF ERMPERDATT
WNAMLSGFCQ SGHTDKAFSL FREMRLNEIT PDSVTVMTLI QSASFEKSLK LLEAMHAVGI
RLGVDVQVTV ANTWISTYGK CGDLDSAKLV FEAIDRGDRT VVSWNSMFKA YSVFGEAFDA
FGLYCLMLRE EFKPDLSTFI NLAASCQNPE TLTQGRLIHS HAIHLGTDQD IEAINTFISM
YSKSEDTCSA RLLFDIMTSR TCVSWTVMIS GYAEKGDMDE ALALFHAMIK SGEKPDLVTL
LSLISGCGKF GSLETGKWID ARADIYGCKR DNVMICNALI DMYSKCGSIH EARDIFDNTP
EKTVVTWTTM IAGYALNGIF LEALKLFSKM IDLDYKPNHI TFLAVLQACA HSGSLEKGWE
YFHIMKQVYN ISPGLDHYSC MVDLLGRKGK LEEALELIRN MSAKPDAGIW GALLNACKIH
RNVKIAEQAA ESLFNLEPQM AAPYVEMANI YAAAGMWDGF ARIRSIMKQR NIKKYPGESV
IQVNGKNHSF TVGEHGHVEN EVIYFTLNGL SLFAKDKHVL YKDVYKEQSY ELFI
