PP324_ARATH
ID PP324_ARATH Reviewed; 951 AA.
AC O49680; F4JT49;
DT 10-FEB-2009, integrated into UniProtKB/Swiss-Prot.
DT 10-FEB-2009, sequence version 2.
DT 03-AUG-2022, entry version 120.
DE RecName: Full=Pentatricopeptide repeat-containing protein At4g19220, mitochondrial;
DE Flags: Precursor;
GN Name=PCMP-E2; OrderedLocusNames=At4g19220; ORFNames=T18B16.190;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617198; DOI=10.1038/47134;
RA Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B.,
RA Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M.,
RA de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M.,
RA Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D.,
RA Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J.,
RA Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B.,
RA Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J.,
RA Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R.,
RA Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S.,
RA Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J.,
RA Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S.,
RA Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A.,
RA Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M.,
RA Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D.,
RA Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S.,
RA Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R.,
RA Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M.,
RA Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H.,
RA Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N.,
RA Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A.,
RA Martienssen R., McCombie W.R.;
RT "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL Nature 402:769-777(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP GENE FAMILY.
RX PubMed=10809006; DOI=10.1023/a:1006352315928;
RA Aubourg S., Boudet N., Kreis M., Lecharny A.;
RT "In Arabidopsis thaliana, 1% of the genome codes for a novel protein family
RT unique to plants.";
RL Plant Mol. Biol. 42:603-613(2000).
RN [4]
RP GENE FAMILY.
RX PubMed=15269332; DOI=10.1105/tpc.104.022236;
RA Lurin C., Andres C., Aubourg S., Bellaoui M., Bitton F., Bruyere C.,
RA Caboche M., Debast C., Gualberto J., Hoffmann B., Lecharny A., Le Ret M.,
RA Martin-Magniette M.-L., Mireau H., Peeters N., Renou J.-P., Szurek B.,
RA Taconnat L., Small I.;
RT "Genome-wide analysis of Arabidopsis pentatricopeptide repeat proteins
RT reveals their essential role in organelle biogenesis.";
RL Plant Cell 16:2089-2103(2004).
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the PPR family. PCMP-E subfamily. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAA16711.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=CAB78924.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC -!- WEB RESOURCE: Name=Pentatricopeptide repeat proteins;
CC URL="https://ppr.plantenergy.uwa.edu.au";
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DR EMBL; AL021687; CAA16711.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AL161550; CAB78924.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002687; AEE84161.2; -; Genomic_DNA.
DR PIR; T04443; T04443.
DR RefSeq; NP_001319994.1; NM_001341331.1.
DR AlphaFoldDB; O49680; -.
DR SMR; O49680; -.
DR PaxDb; O49680; -.
DR PRIDE; O49680; -.
DR EnsemblPlants; AT4G19220.1; AT4G19220.1; AT4G19220.
DR GeneID; 827662; -.
DR Gramene; AT4G19220.1; AT4G19220.1; AT4G19220.
DR KEGG; ath:AT4G19220; -.
DR Araport; AT4G19220; -.
DR eggNOG; KOG4197; Eukaryota.
DR HOGENOM; CLU_002706_15_1_1; -.
DR InParanoid; O49680; -.
DR OMA; MEDFEPN; -.
DR OrthoDB; 1344243at2759; -.
DR PhylomeDB; O49680; -.
DR PRO; PR:O49680; -.
DR Proteomes; UP000006548; Chromosome 4.
DR ExpressionAtlas; O49680; baseline and differential.
DR Genevisible; O49680; AT.
DR GO; GO:0043231; C:intracellular membrane-bounded organelle; IBA:GO_Central.
DR GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR GO; GO:0009451; P:RNA modification; IBA:GO_Central.
DR Gene3D; 1.25.40.10; -; 6.
DR InterPro; IPR002885; Pentatricopeptide_repeat.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR Pfam; PF01535; PPR; 10.
DR Pfam; PF13041; PPR_2; 1.
DR TIGRFAMs; TIGR00756; PPR; 7.
DR PROSITE; PS51375; PPR; 17.
PE 3: Inferred from homology;
KW Mitochondrion; Reference proteome; Repeat; Transit peptide.
FT TRANSIT 1..63
FT /note="Mitochondrion"
FT /evidence="ECO:0000255"
FT CHAIN 64..951
FT /note="Pentatricopeptide repeat-containing protein
FT At4g19220, mitochondrial"
FT /id="PRO_0000363441"
FT REPEAT 121..151
FT /note="PPR 1"
FT REPEAT 152..186
FT /note="PPR 2"
FT REPEAT 187..221
FT /note="PPR 3"
FT REPEAT 222..252
FT /note="PPR 4"
FT REPEAT 253..287
FT /note="PPR 5"
FT REPEAT 288..322
FT /note="PPR 6"
FT REPEAT 325..355
FT /note="PPR 7"
FT REPEAT 356..386
FT /note="PPR 8"
FT REPEAT 392..426
FT /note="PPR 9"
FT REPEAT 428..458
FT /note="PPR 10"
FT REPEAT 459..489
FT /note="PPR 11"
FT REPEAT 496..530
FT /note="PPR 12"
FT REPEAT 531..561
FT /note="PPR 13"
FT REPEAT 563..597
FT /note="PPR 14"
FT REPEAT 599..629
FT /note="PPR 15"
FT REPEAT 634..668
FT /note="PPR 16"
FT REPEAT 669..695
FT /note="PPR 17"
FT REPEAT 697..731
FT /note="PPR 18"
FT REPEAT 732..762
FT /note="PPR 19"
FT REPEAT 763..793
FT /note="PPR 20"
FT REPEAT 799..829
FT /note="PPR 21"
FT REPEAT 835..865
FT /note="PPR 22"
FT REGION 870..945
FT /note="Type E motif"
SQ SEQUENCE 951 AA; 105027 MW; EA20ABD7D88CFC4B CRC64;
MLLVMVRSST ISPKSLRLYC SGHIIDSLRH SISRWNSPSG YCSNYYFSKR KHKRHFTSSV
LSPVTPIVHN LFDELPEREN RTMESSFMFL RDVLRSFMMR TETETPRSVH CFALKCGLLQ
DLATSSKLLT FYGRTGELVS SSCLFDELKE KDVIVWNSMI TALNQNGRYI AAVGLFIEMI
HKGNEFDSTT LLLAASALSS LHLSRKCSML HCLAIETGLV GDSSLCNALM NLYAKGENLS
SAECVFTHME HRDIVSWNTI MTKCLANGHP RKSLQYFKSM TGSGQEADTV TFSCVISACS
SIEELTLGES LHGLVIKSGY SPEAHVSVGN SIISMYSKCG DTEAAETVFE ELVCRDVISS
NAILNGFAAN GMFEEAFGIL NQMQSVDKIQ PDIATVVSIT SICGDLSFSR EGRAVHGYTV
RMEMQSRALE VINSVIDMYG KCGLTTQAEL LFKTTTHRDL VSWNSMISAF SQNGFTHKAK
NLFKEVVSEY SCSKFSLSTV LAILTSCDSS DSLIFGKSVH CWLQKLGFGD NMLSANSVIN
MYIGCRDLTS AFLRLETMSE TRDLTSWNSV ISGCASSGHH LESLRAFQAM SREGKIRHDL
ITLLGTISAS GNLGLVLQGR CFHGLAIKSL RELDTQLQNT LITMYGRCKD IESAVKVFGL
ISDPNLCSWN CVISALSQNK AGREVFQLFR NLKLEPNEIT FVGLLSASTQ LGSTSYGMQA
HCHLIRRGFQ ANPFVSAALV DMYSSCGMLE TGMKVFRNSG VNSISAWNSV ISAHGFHGMG
EKAMELFKEL SSNSEMEPNK SSFISLLSAC SHSGFIDEGL SYYKQMEEKF GVKPVTEHRV
WIVDMLGRAG KLREAYEFIT GIGEPQKAGV WGALLSACNY HGDTKLGKEV AEVLFEMEPD
NASYYISLAN TYVGLGGWEE AVRLRKMVED NALKKLPGYS VIDVRCLDTV S
