ID   ATB22_ARATH             Reviewed;         185 AA.
AC   Q4PSR7; Q9ZQB1;
DT   31-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2005, sequence version 1.
DT   03-AUG-2022, entry version 120.
DE   RecName: Full=Homeobox-leucine zipper protein ATHB-22;
DE   AltName: Full=HD-ZIP protein ATHB-22;
DE   AltName: Full=Homeodomain transcription factor ATHB-22;
GN   Name=ATHB-22; OrderedLocusNames=At2g36610; ORFNames=F13K3.1, F1O11.24;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10617197; DOI=10.1038/45471;
RA   Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA   Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA   Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA   Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA   Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA   Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA   Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT   "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL   Nature 402:761-768(1999).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RA   Underwood B.A., Xiao Y.-L., Moskal W.A. Jr., Monaghan E.L., Wang W.,
RA   Redman J.C., Wu H.C., Utterback T., Town C.D.;
RL   Submitted (MAY-2005) to the EMBL/GenBank/DDBJ databases.
RN   [4]
RP   GENE FAMILY, AND TISSUE SPECIFICITY.
RX   PubMed=16055682; DOI=10.1104/pp.105.063461;
RA   Henriksson E., Olsson A.S.B., Johannesson H., Johansson H., Hanson J.,
RA   Engstroem P., Soederman E.;
RT   "Homeodomain leucine zipper class I genes in Arabidopsis. Expression
RT   patterns and phylogenetic relationships.";
RL   Plant Physiol. 139:509-518(2005).
CC   -!- FUNCTION: Probable transcription factor. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC   -!- TISSUE SPECIFICITY: Expressed in siliques.
CC       {ECO:0000269|PubMed:16055682}.
CC   -!- SIMILARITY: Belongs to the HD-ZIP homeobox family. Class I subfamily.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAD20137.2; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC       Sequence=AAM15313.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; AC006282; AAD20137.2; ALT_SEQ; Genomic_DNA.
DR   EMBL; AC006919; AAM15313.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; CP002685; AEC09273.1; -; Genomic_DNA.
DR   EMBL; DQ056569; AAY78719.1; -; mRNA.
DR   PIR; E84782; E84782.
DR   RefSeq; NP_850266.1; NM_179935.2.
DR   AlphaFoldDB; Q4PSR7; -.
DR   SMR; Q4PSR7; -.
DR   BioGRID; 3577; 12.
DR   STRING; 3702.AT2G36610.1; -.
DR   PaxDb; Q4PSR7; -.
DR   PRIDE; Q4PSR7; -.
DR   EnsemblPlants; AT2G36610.1; AT2G36610.1; AT2G36610.
DR   GeneID; 818233; -.
DR   Gramene; AT2G36610.1; AT2G36610.1; AT2G36610.
DR   KEGG; ath:AT2G36610; -.
DR   Araport; AT2G36610; -.
DR   TAIR; locus:2040520; AT2G36610.
DR   eggNOG; KOG0483; Eukaryota.
DR   HOGENOM; CLU_1505482_0_0_1; -.
DR   InParanoid; Q4PSR7; -.
DR   OMA; DHFSGNQ; -.
DR   OrthoDB; 1467447at2759; -.
DR   PhylomeDB; Q4PSR7; -.
DR   PRO; PR:Q4PSR7; -.
DR   Proteomes; UP000006548; Chromosome 2.
DR   ExpressionAtlas; Q4PSR7; baseline and differential.
DR   Genevisible; Q4PSR7; AT.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IBA:GO_Central.
DR   GO; GO:0000976; F:transcription cis-regulatory region binding; IPI:TAIR.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IBA:GO_Central.
DR   CDD; cd00086; homeodomain; 1.
DR   InterPro; IPR045224; HDZip_class_I_plant.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR017970; Homeobox_CS.
DR   InterPro; IPR001356; Homeobox_dom.
DR   InterPro; IPR000047; HTH_motif.
DR   PANTHER; PTHR24326; PTHR24326; 1.
DR   Pfam; PF00046; Homeodomain; 1.
DR   PRINTS; PR00031; HTHREPRESSR.
DR   SMART; SM00389; HOX; 1.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   PROSITE; PS00027; HOMEOBOX_1; 1.
DR   PROSITE; PS50071; HOMEOBOX_2; 1.
PE   2: Evidence at transcript level;
KW   DNA-binding; Homeobox; Nucleus; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..185
FT                   /note="Homeobox-leucine zipper protein ATHB-22"
FT                   /id="PRO_0000257799"
FT   DNA_BIND        76..135
FT                   /note="Homeobox"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00108"
FT   REGION          136..164
FT                   /note="Leucine-zipper"
SQ   SEQUENCE   185 AA;  21832 MW;  D86C01FB6D8997BA CRC64;
     MEYWSSSFID GASSSSFISP FYNFDHFSGN QDNRCLGTMM GAQQDILHVP LAMVESGYGE
     ESNSFNGQEK KKKKMTSEQL KFLERSFQEE IKLNPDRKMK LNPDRKMKLS KELGLQPRQI
     AVWFQNRKAR WKNKQLEHLY ESLRQEFDIV SREKELLQEE LIQLKSMIRE DSSCKKKQTW
     EKACS