ID   PP335_ARATH             Reviewed;         843 AA.
AC   O49711;
DT   10-FEB-2009, integrated into UniProtKB/Swiss-Prot.
DT   10-FEB-2009, sequence version 2.
DT   25-MAY-2022, entry version 111.
DE   RecName: Full=Pentatricopeptide repeat-containing protein At4g21880, mitochondrial;
DE   Flags: Precursor;
GN   OrderedLocusNames=At4g21880; ORFNames=T8O5.90;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10617198; DOI=10.1038/47134;
RA   Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA   Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B.,
RA   Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M.,
RA   de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M.,
RA   Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D.,
RA   Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J.,
RA   Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B.,
RA   Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J.,
RA   Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R.,
RA   Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA   Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA   Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S.,
RA   Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA   Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J.,
RA   Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S.,
RA   Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A.,
RA   Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M.,
RA   Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M.,
RA   Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D.,
RA   Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA   Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S.,
RA   Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R.,
RA   Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA   Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA   Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA   Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA   Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA   de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA   Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M.,
RA   Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA   Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA   Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA   Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA   Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H.,
RA   Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA   Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA   Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA   O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N.,
RA   Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A.,
RA   Martienssen R., McCombie W.R.;
RT   "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL   Nature 402:769-777(1999).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   GENE FAMILY.
RX   PubMed=15269332; DOI=10.1105/tpc.104.022236;
RA   Lurin C., Andres C., Aubourg S., Bellaoui M., Bitton F., Bruyere C.,
RA   Caboche M., Debast C., Gualberto J., Hoffmann B., Lecharny A., Le Ret M.,
RA   Martin-Magniette M.-L., Mireau H., Peeters N., Renou J.-P., Szurek B.,
RA   Taconnat L., Small I.;
RT   "Genome-wide analysis of Arabidopsis pentatricopeptide repeat proteins
RT   reveals their essential role in organelle biogenesis.";
RL   Plant Cell 16:2089-2103(2004).
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the PPR family. P subfamily. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAA17155.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC       Sequence=CAB79143.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC   -!- WEB RESOURCE: Name=Pentatricopeptide repeat proteins;
CC       URL="https://ppr.plantenergy.uwa.edu.au";
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DR   EMBL; AL021890; CAA17155.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; AL161556; CAB79143.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; CP002687; AEE84518.1; -; Genomic_DNA.
DR   PIR; T05470; T05470.
DR   RefSeq; NP_193919.6; NM_118309.7.
DR   AlphaFoldDB; O49711; -.
DR   SMR; O49711; -.
DR   PaxDb; O49711; -.
DR   PRIDE; O49711; -.
DR   ProteomicsDB; 249235; -.
DR   EnsemblPlants; AT4G21880.1; AT4G21880.1; AT4G21880.
DR   GeneID; 828277; -.
DR   Gramene; AT4G21880.1; AT4G21880.1; AT4G21880.
DR   KEGG; ath:AT4G21880; -.
DR   Araport; AT4G21880; -.
DR   TAIR; locus:2141642; AT4G21880.
DR   eggNOG; KOG4197; Eukaryota.
DR   HOGENOM; CLU_013098_0_0_1; -.
DR   InParanoid; O49711; -.
DR   OrthoDB; 1344243at2759; -.
DR   PRO; PR:O49711; -.
DR   Proteomes; UP000006548; Chromosome 4.
DR   ExpressionAtlas; O49711; baseline and differential.
DR   GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR   Gene3D; 1.25.40.10; -; 3.
DR   InterPro; IPR002885; Pentatricopeptide_repeat.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   Pfam; PF01535; PPR; 2.
DR   Pfam; PF13041; PPR_2; 1.
DR   TIGRFAMs; TIGR00756; PPR; 2.
DR   PROSITE; PS51375; PPR; 6.
PE   3: Inferred from homology;
KW   Mitochondrion; Reference proteome; Repeat; Transit peptide.
FT   TRANSIT         1..?
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           ?..843
FT                   /note="Pentatricopeptide repeat-containing protein
FT                   At4g21880, mitochondrial"
FT                   /id="PRO_0000363452"
FT   REPEAT          392..426
FT                   /note="PPR 1"
FT   REPEAT          427..461
FT                   /note="PPR 2"
FT   REPEAT          462..496
FT                   /note="PPR 3"
FT   REPEAT          497..531
FT                   /note="PPR 4"
FT   REPEAT          532..562
FT                   /note="PPR 5"
FT   REPEAT          564..594
FT                   /note="PPR 6"
FT   REPEAT          598..632
FT                   /note="PPR 7"
SQ   SEQUENCE   843 AA;  94761 MW;  EA09C5CEA821A92E CRC64;
     MALKAKKSLS AIFRFAMRNA AKTAEVEAKA VAGDSLISDT GPVSMSLIPD FLSSLKSPED
     SSNIGQDFGE PALAGQVSSA LDVKSIGYNL LRERNGEKVF PKNVLETLDL LSRKGCSSQK
     PKQASRGRML TENYQNKQSE IMEKLAKGCV RKLGTETMFE VLTKMGKEAG EKEYNAMTKL
     CIQRARRSND AEYALDQIGK AIEHLKEMRQ LGFSIGEGAY GPFFKYLVDM EMVAEFQILK
     DFIKEACPES CGRLVYYEML LWIQVNDEEK IHKLCNKVDD SGLSLSILQE YYLVALCEKD
     SKENFQKLLE IVDITTVSSP DALKSIFGYL GKSLLESVAM KLLWELRDCR KDGVETVSNL
     IFSYATCIPN STVEDAIFKF NKLHEELDIV PSSTSYENLV SYLCGSNEVV TALDIVENMC
     EAGLVISANI LHSLLQAIEQ ILEFNLVQRI YSIMSNKSVK PNSETFRKSI NLCIRIKDFE
     GAYNMLGNLK NFNLAPNSSM YNSIMAGYFR EKKVNSALKV LKEMKEADVK PDSVTFSYLI
     NYCGEEATIA KYYKEMKQAG VEVNKHVYMS LVKAYASCGQ FEKAKQVLMD LEVPAKDHNE
     LKSVLISALA SNGNITEALS IYEEMKKLRC PVEPKAILSL IENSDSNAEL GTLVELTHEL
     RDSKFWIDGF FKIIVFAVRN NRSSSILDLL EQTKNHLSKD DVGVEYWFEE VFKSIAETES
     SDVKVGLDLV SFMKEELELC PSRKCLDFLL HACVNAKDKQ SALLVWEEYQ CAELPYNVIN
     YLRMYQVLVA AGDSKSAEAI VSKIPNDDKD VKCIIKESRI VFTPKLKKKK KKSKQKGLSL
     QAK