PP336_ARATH
ID PP336_ARATH Reviewed; 578 AA.
AC P0C8Q5; O49657;
DT 10-FEB-2009, integrated into UniProtKB/Swiss-Prot.
DT 10-FEB-2009, sequence version 1.
DT 25-MAY-2022, entry version 78.
DE RecName: Full=Pentatricopeptide repeat-containing protein At4g22760;
GN Name=PCMP-E6; OrderedLocusNames=At4g22760; ORFNames=T12H17.150;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617198; DOI=10.1038/47134;
RA Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B.,
RA Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M.,
RA de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M.,
RA Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D.,
RA Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J.,
RA Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B.,
RA Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J.,
RA Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R.,
RA Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S.,
RA Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J.,
RA Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S.,
RA Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A.,
RA Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M.,
RA Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D.,
RA Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S.,
RA Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R.,
RA Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M.,
RA Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H.,
RA Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N.,
RA Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A.,
RA Martienssen R., McCombie W.R.;
RT "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL Nature 402:769-777(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP GENE FAMILY.
RX PubMed=10809006; DOI=10.1023/a:1006352315928;
RA Aubourg S., Boudet N., Kreis M., Lecharny A.;
RT "In Arabidopsis thaliana, 1% of the genome codes for a novel protein family
RT unique to plants.";
RL Plant Mol. Biol. 42:603-613(2000).
RN [4]
RP GENE FAMILY.
RX PubMed=15269332; DOI=10.1105/tpc.104.022236;
RA Lurin C., Andres C., Aubourg S., Bellaoui M., Bitton F., Bruyere C.,
RA Caboche M., Debast C., Gualberto J., Hoffmann B., Lecharny A., Le Ret M.,
RA Martin-Magniette M.-L., Mireau H., Peeters N., Renou J.-P., Szurek B.,
RA Taconnat L., Small I.;
RT "Genome-wide analysis of Arabidopsis pentatricopeptide repeat proteins
RT reveals their essential role in organelle biogenesis.";
RL Plant Cell 16:2089-2103(2004).
CC -!- SIMILARITY: Belongs to the PPR family. PCMP-E subfamily. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAA16561.1; Type=Erroneous gene model prediction; Note=The predicted gene has been split into 2 genes: At4g22758 and At4g22760.; Evidence={ECO:0000305};
CC Sequence=CAB79231.1; Type=Erroneous gene model prediction; Note=The predicted gene has been split into 2 genes: At4g22758 and At4g22760.; Evidence={ECO:0000305};
CC -!- WEB RESOURCE: Name=Pentatricopeptide repeat proteins;
CC URL="https://ppr.plantenergy.uwa.edu.au";
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AL021635; CAA16561.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AL161557; CAB79231.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002687; AEE84655.1; -; Genomic_DNA.
DR PIR; T04571; T04571.
DR RefSeq; NP_194007.2; NM_118405.3.
DR AlphaFoldDB; P0C8Q5; -.
DR SMR; P0C8Q5; -.
DR STRING; 3702.AT4G22760.1; -.
DR PaxDb; P0C8Q5; -.
DR PRIDE; P0C8Q5; -.
DR ProteomicsDB; 249236; -.
DR EnsemblPlants; AT4G22760.1; AT4G22760.1; AT4G22760.
DR GeneID; 828375; -.
DR Gramene; AT4G22760.1; AT4G22760.1; AT4G22760.
DR KEGG; ath:AT4G22760; -.
DR Araport; AT4G22760; -.
DR TAIR; locus:2132589; AT4G22760.
DR eggNOG; KOG4197; Eukaryota.
DR HOGENOM; CLU_002706_0_6_1; -.
DR InParanoid; P0C8Q5; -.
DR OMA; QLIMQMP; -.
DR OrthoDB; 1153302at2759; -.
DR PRO; PR:P0C8Q5; -.
DR Proteomes; UP000006548; Chromosome 4.
DR ExpressionAtlas; P0C8Q5; baseline and differential.
DR Genevisible; P0C8Q5; AT.
DR GO; GO:0043231; C:intracellular membrane-bounded organelle; IBA:GO_Central.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR GO; GO:0009451; P:RNA modification; IBA:GO_Central.
DR Gene3D; 1.25.40.10; -; 3.
DR InterPro; IPR002885; Pentatricopeptide_repeat.
DR InterPro; IPR045215; PPR_prot_plant.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR PANTHER; PTHR24015; PTHR24015; 3.
DR Pfam; PF01535; PPR; 7.
DR Pfam; PF13041; PPR_2; 2.
DR SUPFAM; SSF48452; SSF48452; 2.
DR TIGRFAMs; TIGR00756; PPR; 9.
DR PROSITE; PS51375; PPR; 14.
PE 2: Evidence at transcript level;
KW Reference proteome; Repeat.
FT CHAIN 1..578
FT /note="Pentatricopeptide repeat-containing protein
FT At4g22760"
FT /id="PRO_0000363453"
FT REPEAT 68..102
FT /note="PPR 1"
FT REPEAT 103..137
FT /note="PPR 2"
FT REPEAT 138..168
FT /note="PPR 3"
FT REPEAT 169..203
FT /note="PPR 4"
FT REPEAT 204..230
FT /note="PPR 5"
FT REPEAT 231..261
FT /note="PPR 6"
FT REPEAT 262..292
FT /note="PPR 7"
FT REPEAT 293..327
FT /note="PPR 8"
FT REPEAT 330..364
FT /note="PPR 9"
FT REPEAT 365..395
FT /note="PPR 10"
FT REPEAT 396..430
FT /note="PPR 11"
FT REPEAT 431..465
FT /note="PPR 12"
FT REPEAT 466..496
FT /note="PPR 13"
FT REGION 501..576
FT /note="Type E motif"
SQ SEQUENCE 578 AA; 64586 MW; 530EE300A04C6E1C CRC64;
MLDSKLRFFL QRCVVLEQAK QVHAQLVVNR YNHLEPILVH QTLHFTKEFS RNIVTYVKRI
LKGFNGHDSF SWGCLVRFLS QHRKFKETVD VYIDMHNSGI PPSSHAVTSV LRACGKMENM
VDGKPIHAQA LKNGLCGCVY VQTGLVGLYS RLGYIELAKK AFDDIAEKNT VSWNSLLHGY
LESGELDEAR RVFDKIPEKD AVSWNLIISS YAKKGDMGNA CSLFSAMPLK SPASWNILIG
GYVNCREMKL ARTYFDAMPQ KNGVSWITMI SGYTKLGDVQ SAEELFRLMS KKDKLVYDAM
IACYTQNGKP KDALKLFAQM LERNSYIQPD EITLSSVVSA NSQLGNTSFG TWVESYITEH
GIKIDDLLST SLIDLYMKGG DFAKAFKMFS NLNKKDTVSY SAMIMGCGIN GMATEANSLF
TAMIEKKIPP NVVTFTGLLS AYSHSGLVQE GYKCFNSMKD HNLEPSADHY GIMVDMLGRA
GRLEEAYELI KSMPMQPNAG VWGALLLASG LHNNVEFGEI ACSHCVKLET DPTGYLSHLA
MIYSSVGRWD DARTVRDSIK EKKLCKTLGC SWVEGSYH
