ID   ATB23_ARATH             Reviewed;         255 AA.
AC   Q8LFD3; Q9ZVG2;
DT   31-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2002, sequence version 1.
DT   25-MAY-2022, entry version 129.
DE   RecName: Full=Homeobox-leucine zipper protein ATHB-23;
DE   AltName: Full=HD-ZIP protein ATHB-23;
DE   AltName: Full=Homeodomain transcription factor ATHB-23;
GN   Name=ATHB-23; OrderedLocusNames=At1g26960; ORFNames=T2P11.15;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=11130712; DOI=10.1038/35048500;
RA   Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA   Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA   Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA   Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA   Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA   Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA   Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA   Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA   Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA   Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA   Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA   Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA   Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA   Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA   Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT   "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL   Nature 408:816-820(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=14593172; DOI=10.1126/science.1088305;
RA   Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA   Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA   Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA   Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA   Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA   Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA   Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA   Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA   Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA   Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA   Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA   Ecker J.R.;
RT   "Empirical analysis of transcriptional activity in the Arabidopsis
RT   genome.";
RL   Science 302:842-846(2003).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RA   Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA   Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA   Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA   Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA   Shinozaki K.;
RT   "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL   Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN   [5]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA   Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA   Feldmann K.A.;
RT   "Full-length cDNA from Arabidopsis thaliana.";
RL   Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN   [6]
RP   GENE FAMILY, AND TISSUE SPECIFICITY.
RX   PubMed=16055682; DOI=10.1104/pp.105.063461;
RA   Henriksson E., Olsson A.S.B., Johannesson H., Johansson H., Hanson J.,
RA   Engstroem P., Soederman E.;
RT   "Homeodomain leucine zipper class I genes in Arabidopsis. Expression
RT   patterns and phylogenetic relationships.";
RL   Plant Physiol. 139:509-518(2005).
RN   [7]
RP   TISSUE SPECIFICITY, AND INDUCTION.
RX   PubMed=17387478; DOI=10.1007/s00299-007-0340-9;
RA   Kim Y.-K., Son O., Kim M.-R., Nam K.-H., Kim G.-T., Lee M.-S., Choi S.-Y.,
RA   Cheon C.-I.;
RT   "ATHB23, an Arabidopsis class I homeodomain-leucine zipper gene, is
RT   expressed in the adaxial region of young leaves.";
RL   Plant Cell Rep. 26:1179-1185(2007).
CC   -!- FUNCTION: Probable transcription factor. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC   -!- TISSUE SPECIFICITY: Expressed in young leaves, in the adaxial domain of
CC       leaf primordia and the rib meristem. Expressed in the styles of flowers
CC       and siliques. {ECO:0000269|PubMed:16055682,
CC       ECO:0000269|PubMed:17387478}.
CC   -!- INDUCTION: By gibberellic acid (GA3). {ECO:0000269|PubMed:17387478}.
CC   -!- SIMILARITY: Belongs to the HD-ZIP homeobox family. Class I subfamily.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAD14502.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; AC005508; AAD14502.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; CP002684; AEE30764.1; -; Genomic_DNA.
DR   EMBL; BT009727; AAP88361.1; -; mRNA.
DR   EMBL; AK228056; BAF00017.1; -; mRNA.
DR   EMBL; AY084913; AAM61475.1; -; mRNA.
DR   PIR; F86396; F86396.
DR   RefSeq; NP_564268.1; NM_102460.4.
DR   AlphaFoldDB; Q8LFD3; -.
DR   SMR; Q8LFD3; -.
DR   BioGRID; 24822; 11.
DR   STRING; 3702.AT1G26960.1; -.
DR   PaxDb; Q8LFD3; -.
DR   PRIDE; Q8LFD3; -.
DR   ProteomicsDB; 246535; -.
DR   EnsemblPlants; AT1G26960.1; AT1G26960.1; AT1G26960.
DR   GeneID; 839587; -.
DR   Gramene; AT1G26960.1; AT1G26960.1; AT1G26960.
DR   KEGG; ath:AT1G26960; -.
DR   Araport; AT1G26960; -.
DR   TAIR; locus:2202795; AT1G26960.
DR   eggNOG; KOG0483; Eukaryota.
DR   HOGENOM; CLU_060842_4_0_1; -.
DR   InParanoid; Q8LFD3; -.
DR   OMA; NMNGEDE; -.
DR   OrthoDB; 1227444at2759; -.
DR   PhylomeDB; Q8LFD3; -.
DR   PRO; PR:Q8LFD3; -.
DR   Proteomes; UP000006548; Chromosome 1.
DR   ExpressionAtlas; Q8LFD3; baseline and differential.
DR   Genevisible; Q8LFD3; AT.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IBA:GO_Central.
DR   GO; GO:0000976; F:transcription cis-regulatory region binding; IPI:TAIR.
DR   GO; GO:0048527; P:lateral root development; IMP:TAIR.
DR   GO; GO:0010311; P:lateral root formation; IDA:TAIR.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IBA:GO_Central.
DR   GO; GO:0009739; P:response to gibberellin; IEP:TAIR.
DR   GO; GO:0022622; P:root system development; IDA:TAIR.
DR   CDD; cd00086; homeodomain; 1.
DR   InterPro; IPR045224; HDZip_class_I_plant.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR017970; Homeobox_CS.
DR   InterPro; IPR001356; Homeobox_dom.
DR   InterPro; IPR000047; HTH_motif.
DR   InterPro; IPR003106; Leu_zip_homeo.
DR   PANTHER; PTHR24326; PTHR24326; 2.
DR   Pfam; PF02183; HALZ; 1.
DR   Pfam; PF00046; Homeodomain; 1.
DR   PRINTS; PR00031; HTHREPRESSR.
DR   SMART; SM00340; HALZ; 1.
DR   SMART; SM00389; HOX; 1.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   PROSITE; PS00027; HOMEOBOX_1; 1.
DR   PROSITE; PS50071; HOMEOBOX_2; 1.
PE   2: Evidence at transcript level;
KW   DNA-binding; Homeobox; Nucleus; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..255
FT                   /note="Homeobox-leucine zipper protein ATHB-23"
FT                   /id="PRO_0000257800"
FT   DNA_BIND        68..127
FT                   /note="Homeobox"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00108"
FT   REGION          128..163
FT                   /note="Leucine-zipper"
SQ   SEQUENCE   255 AA;  29663 MW;  4A131B988E29D75C CRC64;
     MSCNNNGLAF FPENFSLQNH HQEEEDHPQL LQDFHGFLGK RSPMNNVQGF CNLDMNGDEE
     YSDDGSKMGE KKRRLNMEQL KALEKDFELG NKLESDRKLE LARALGLQPR QIAIWFQNRR
     ARSKTKQLEK DYDMLKRQFE SLRDENEVLQ TQNQKLQAQV MALKSREPIE SINLNKETEG
     SCSDRSENIS GDIRPPEIDS QFALGHPPTT TTMQFFQNSS SEQRMVKEEN SISNMFCGID
     DQSGFWPWLD QQQYN