PP353_ARATH
ID PP353_ARATH Reviewed; 691 AA.
AC O23169;
DT 10-FEB-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1998, sequence version 1.
DT 03-AUG-2022, entry version 124.
DE RecName: Full=Pentatricopeptide repeat-containing protein At4g37170;
GN Name=PCMP-H5; OrderedLocusNames=At4g37170; ORFNames=AP22.43, C7A10.190;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=9461215; DOI=10.1038/35140;
RA Bevan M., Bancroft I., Bent E., Love K., Goodman H.M., Dean C.,
RA Bergkamp R., Dirkse W., van Staveren M., Stiekema W., Drost L., Ridley P.,
RA Hudson S.-A., Patel K., Murphy G., Piffanelli P., Wedler H., Wedler E.,
RA Wambutt R., Weitzenegger T., Pohl T., Terryn N., Gielen J., Villarroel R.,
RA De Clercq R., van Montagu M., Lecharny A., Aubourg S., Gy I., Kreis M.,
RA Lao N., Kavanagh T., Hempel S., Kotter P., Entian K.-D., Rieger M.,
RA Schaefer M., Funk B., Mueller-Auer S., Silvey M., James R., Monfort A.,
RA Pons A., Puigdomenech P., Douka A., Voukelatou E., Milioni D.,
RA Hatzopoulos P., Piravandi E., Obermaier B., Hilbert H., Duesterhoeft A.,
RA Moores T., Jones J.D.G., Eneva T., Palme K., Benes V., Rechmann S.,
RA Ansorge W., Cooke R., Berger C., Delseny M., Voet M., Volckaert G.,
RA Mewes H.-W., Klosterman S., Schueller C., Chalwatzis N.;
RT "Analysis of 1.9 Mb of contiguous sequence from chromosome 4 of Arabidopsis
RT thaliana.";
RL Nature 391:485-488(1998).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617198; DOI=10.1038/47134;
RA Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B.,
RA Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M.,
RA de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M.,
RA Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D.,
RA Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J.,
RA Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B.,
RA Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J.,
RA Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R.,
RA Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S.,
RA Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J.,
RA Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S.,
RA Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A.,
RA Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M.,
RA Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D.,
RA Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S.,
RA Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R.,
RA Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M.,
RA Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H.,
RA Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N.,
RA Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A.,
RA Martienssen R., McCombie W.R.;
RT "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL Nature 402:769-777(1999).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP GENE FAMILY.
RX PubMed=10809006; DOI=10.1023/a:1006352315928;
RA Aubourg S., Boudet N., Kreis M., Lecharny A.;
RT "In Arabidopsis thaliana, 1% of the genome codes for a novel protein family
RT unique to plants.";
RL Plant Mol. Biol. 42:603-613(2000).
RN [5]
RP GENE FAMILY.
RX PubMed=15269332; DOI=10.1105/tpc.104.022236;
RA Lurin C., Andres C., Aubourg S., Bellaoui M., Bitton F., Bruyere C.,
RA Caboche M., Debast C., Gualberto J., Hoffmann B., Lecharny A., Le Ret M.,
RA Martin-Magniette M.-L., Mireau H., Peeters N., Renou J.-P., Szurek B.,
RA Taconnat L., Small I.;
RT "Genome-wide analysis of Arabidopsis pentatricopeptide repeat proteins
RT reveals their essential role in organelle biogenesis.";
RL Plant Cell 16:2089-2103(2004).
CC -!- SIMILARITY: Belongs to the PPR family. PCMP-H subfamily. {ECO:0000305}.
CC -!- WEB RESOURCE: Name=Pentatricopeptide repeat proteins;
CC URL="https://ppr.plantenergy.uwa.edu.au";
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DR EMBL; Z99707; CAB16758.1; -; Genomic_DNA.
DR EMBL; AL161590; CAB80383.1; -; Genomic_DNA.
DR EMBL; CP002687; AEE86761.1; -; Genomic_DNA.
DR PIR; B85439; B85439.
DR RefSeq; NP_195434.1; NM_119880.2.
DR AlphaFoldDB; O23169; -.
DR SMR; O23169; -.
DR STRING; 3702.AT4G37170.1; -.
DR PaxDb; O23169; -.
DR PRIDE; O23169; -.
DR ProteomicsDB; 249247; -.
DR EnsemblPlants; AT4G37170.1; AT4G37170.1; AT4G37170.
DR GeneID; 829871; -.
DR Gramene; AT4G37170.1; AT4G37170.1; AT4G37170.
DR KEGG; ath:AT4G37170; -.
DR Araport; AT4G37170; -.
DR TAIR; locus:2115130; AT4G37170.
DR eggNOG; KOG4197; Eukaryota.
DR HOGENOM; CLU_002706_15_1_1; -.
DR InParanoid; O23169; -.
DR OMA; RMQEEPG; -.
DR OrthoDB; 1344243at2759; -.
DR PhylomeDB; O23169; -.
DR PRO; PR:O23169; -.
DR Proteomes; UP000006548; Chromosome 4.
DR ExpressionAtlas; O23169; baseline and differential.
DR Genevisible; O23169; AT.
DR GO; GO:0043231; C:intracellular membrane-bounded organelle; IBA:GO_Central.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0009451; P:RNA modification; IBA:GO_Central.
DR Gene3D; 1.25.40.10; -; 5.
DR InterPro; IPR032867; DYW_dom.
DR InterPro; IPR002885; Pentatricopeptide_repeat.
DR InterPro; IPR045215; PPR_prot_plant.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR PANTHER; PTHR24015; PTHR24015; 1.
DR Pfam; PF14432; DYW_deaminase; 1.
DR Pfam; PF01535; PPR; 6.
DR Pfam; PF13041; PPR_2; 2.
DR SUPFAM; SSF48452; SSF48452; 1.
DR TIGRFAMs; TIGR00756; PPR; 6.
DR PROSITE; PS51375; PPR; 13.
PE 3: Inferred from homology;
KW Reference proteome; Repeat.
FT CHAIN 1..691
FT /note="Pentatricopeptide repeat-containing protein
FT At4g37170"
FT /id="PRO_0000363470"
FT REPEAT 84..118
FT /note="PPR 1"
FT REPEAT 119..149
FT /note="PPR 2"
FT REPEAT 150..184
FT /note="PPR 3"
FT REPEAT 185..211
FT /note="PPR 4"
FT REPEAT 217..251
FT /note="PPR 5"
FT REPEAT 252..286
FT /note="PPR 6"
FT REPEAT 287..317
FT /note="PPR 7"
FT REPEAT 318..352
FT /note="PPR 8"
FT REPEAT 353..383
FT /note="PPR 9"
FT REPEAT 384..418
FT /note="PPR 10"
FT REPEAT 419..449
FT /note="PPR 11"
FT REPEAT 455..485
FT /note="PPR 12"
FT REGION 490..565
FT /note="Type E motif"
FT REGION 566..596
FT /note="Type E(+) motif"
FT REGION 597..691
FT /note="Type DYW motif"
SQ SEQUENCE 691 AA; 78026 MW; 08CE0FE7ED76E1C8 CRC64;
MNHSNARKLT TLHGFILKRN LSSFHASLKR FSDKKFFNPN HEDGGVVVER LCRANRFGEA
IDVLCGQKLL REAVQLLGRA KKPPASTYCN LIQVCSQTRA LEEGKKVHEH IRTSGFVPGI
VIWNRLLRMY AKCGSLVDAR KVFDEMPNRD LCSWNVMVNG YAEVGLLEEA RKLFDEMTEK
DSYSWTAMVT GYVKKDQPEE ALVLYSLMQR VPNSRPNIFT VSIAVAAAAA VKCIRRGKEI
HGHIVRAGLD SDEVLWSSLM DMYGKCGCID EARNIFDKIV EKDVVSWTSM IDRYFKSSRW
REGFSLFSEL VGSCERPNEY TFAGVLNACA DLTTEELGKQ VHGYMTRVGF DPYSFASSSL
VDMYTKCGNI ESAKHVVDGC PKPDLVSWTS LIGGCAQNGQ PDEALKYFDL LLKSGTKPDH
VTFVNVLSAC THAGLVEKGL EFFYSITEKH RLSHTSDHYT CLVDLLARSG RFEQLKSVIS
EMPMKPSKFL WASVLGGCST YGNIDLAEEA AQELFKIEPE NPVTYVTMAN IYAAAGKWEE
EGKMRKRMQE IGVTKRPGSS WTEIKRKRHV FIAADTSHPM YNQIVEFLRE LRKKMKEEGY
VPATSLVLHD VEDEQKEENL VYHSEKLAVA FAILSTEEGT AIKVFKNLRS CVDCHGAIKF
ISNITKRKIT VRDSTRFHCF ENGQCSCGDY W
