ID   PP363_ARATH             Reviewed;         896 AA.
AC   Q9FFN1; Q9LZC7;
DT   10-FEB-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   03-AUG-2022, entry version 119.
DE   RecName: Full=Pentatricopeptide repeat-containing protein At5g03800;
DE   AltName: Full=Protein EMBRYO DEFECTIVE 175;
GN   Name=EMB175; Synonyms=PCMP-H19; OrderedLocusNames=At5g03800;
GN   ORFNames=F8F6_10, MED24_10;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA], AND FUNCTION.
RX   PubMed=15647901; DOI=10.1007/s00425-004-1452-x;
RA   Cushing D.A., Forsthoefel N.R., Gestaut D.R., Vernon D.M.;
RT   "Arabidopsis emb175 and other ppr knockout mutants reveal essential roles
RT   for pentatricopeptide repeat (PPR) proteins in plant embryogenesis.";
RL   Planta 221:424-436(2005).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=9330910; DOI=10.1093/dnares/4.3.215;
RA   Sato S., Kotani H., Nakamura Y., Kaneko T., Asamizu E., Fukami M.,
RA   Miyajima N., Tabata S.;
RT   "Structural analysis of Arabidopsis thaliana chromosome 5. I. Sequence
RT   features of the 1.6 Mb regions covered by twenty physically assigned P1
RT   clones.";
RL   DNA Res. 4:215-230(1997).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] OF 1-837.
RC   STRAIN=cv. Columbia;
RX   PubMed=11130714; DOI=10.1038/35048507;
RA   Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E.,
RA   Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M.,
RA   Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K.,
RA   Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M.,
RA   Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L.,
RA   O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D.,
RA   Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M.,
RA   Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L.,
RA   Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B.,
RA   Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P.,
RA   Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M.,
RA   Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D.,
RA   Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A.,
RA   Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I.,
RA   Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T.,
RA   Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A.,
RA   McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U.,
RA   Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W.,
RA   Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M.,
RA   Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S.,
RA   Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G.,
RA   Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W.,
RA   Bevan M., Fransz P.F.;
RT   "Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana.";
RL   Nature 408:823-826(2000).
RN   [4]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [5]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=11910074; DOI=10.1126/science.1071006;
RA   Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA   Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA   Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA   Shinagawa A., Shinozaki K.;
RT   "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL   Science 296:141-145(2002).
RN   [6]
RP   GENE FAMILY.
RX   PubMed=10809006; DOI=10.1023/a:1006352315928;
RA   Aubourg S., Boudet N., Kreis M., Lecharny A.;
RT   "In Arabidopsis thaliana, 1% of the genome codes for a novel protein family
RT   unique to plants.";
RL   Plant Mol. Biol. 42:603-613(2000).
RN   [7]
RP   GENE FAMILY.
RX   PubMed=15269332; DOI=10.1105/tpc.104.022236;
RA   Lurin C., Andres C., Aubourg S., Bellaoui M., Bitton F., Bruyere C.,
RA   Caboche M., Debast C., Gualberto J., Hoffmann B., Lecharny A., Le Ret M.,
RA   Martin-Magniette M.-L., Mireau H., Peeters N., Renou J.-P., Szurek B.,
RA   Taconnat L., Small I.;
RT   "Genome-wide analysis of Arabidopsis pentatricopeptide repeat proteins
RT   reveals their essential role in organelle biogenesis.";
RL   Plant Cell 16:2089-2103(2004).
CC   -!- FUNCTION: May play a role in embryogenesis.
CC       {ECO:0000269|PubMed:15647901}.
CC   -!- SIMILARITY: Belongs to the PPR family. PCMP-H subfamily. {ECO:0000305}.
CC   -!- WEB RESOURCE: Name=Pentatricopeptide repeat proteins;
CC       URL="https://ppr.plantenergy.uwa.edu.au";
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DR   EMBL; AY864345; AAW62960.1; -; mRNA.
DR   EMBL; AY864346; AAW62961.1; -; Genomic_DNA.
DR   EMBL; AB005235; BAB08606.1; -; Genomic_DNA.
DR   EMBL; AL162873; CAB85500.1; -; Genomic_DNA.
DR   EMBL; CP002688; AED90656.1; -; Genomic_DNA.
DR   EMBL; AK117204; BAC41880.1; -; mRNA.
DR   PIR; T48407; T48407.
DR   RefSeq; NP_196000.2; NM_120461.4.
DR   AlphaFoldDB; Q9FFN1; -.
DR   SMR; Q9FFN1; -.
DR   STRING; 3702.AT5G03800.1; -.
DR   PaxDb; Q9FFN1; -.
DR   PRIDE; Q9FFN1; -.
DR   ProteomicsDB; 249253; -.
DR   EnsemblPlants; AT5G03800.1; AT5G03800.1; AT5G03800.
DR   GeneID; 831717; -.
DR   Gramene; AT5G03800.1; AT5G03800.1; AT5G03800.
DR   KEGG; ath:AT5G03800; -.
DR   Araport; AT5G03800; -.
DR   TAIR; locus:2150690; AT5G03800.
DR   eggNOG; KOG4197; Eukaryota.
DR   HOGENOM; CLU_002706_15_1_1; -.
DR   InParanoid; Q9FFN1; -.
DR   OMA; SGFHCFS; -.
DR   OrthoDB; 1344243at2759; -.
DR   PhylomeDB; Q9FFN1; -.
DR   PRO; PR:Q9FFN1; -.
DR   Proteomes; UP000006548; Chromosome 5.
DR   ExpressionAtlas; Q9FFN1; baseline and differential.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0009793; P:embryo development ending in seed dormancy; IMP:TAIR.
DR   Gene3D; 1.25.40.10; -; 6.
DR   InterPro; IPR032867; DYW_dom.
DR   InterPro; IPR002885; Pentatricopeptide_repeat.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   Pfam; PF14432; DYW_deaminase; 1.
DR   Pfam; PF01535; PPR; 4.
DR   Pfam; PF13041; PPR_2; 4.
DR   TIGRFAMs; TIGR00756; PPR; 5.
DR   PROSITE; PS51375; PPR; 16.
PE   2: Evidence at transcript level;
KW   Reference proteome; Repeat.
FT   CHAIN           1..896
FT                   /note="Pentatricopeptide repeat-containing protein
FT                   At5g03800"
FT                   /id="PRO_0000363500"
FT   REPEAT          113..143
FT                   /note="PPR 1"
FT   REPEAT          144..178
FT                   /note="PPR 2"
FT   REPEAT          180..214
FT                   /note="PPR 3"
FT   REPEAT          215..247
FT                   /note="PPR 4"
FT   REPEAT          248..278
FT                   /note="PPR 5"
FT   REPEAT          284..318
FT                   /note="PPR 6"
FT   REPEAT          319..349
FT                   /note="PPR 7"
FT   REPEAT          350..380
FT                   /note="PPR 8"
FT   REPEAT          381..415
FT                   /note="PPR 9"
FT   REPEAT          416..450
FT                   /note="PPR 10"
FT   REPEAT          451..481
FT                   /note="PPR 11"
FT   REPEAT          484..519
FT                   /note="PPR 12"
FT   REPEAT          520..554
FT                   /note="PPR 13"
FT   REPEAT          555..585
FT                   /note="PPR 14"
FT   REPEAT          586..620
FT                   /note="PPR 15"
FT   REPEAT          621..653
FT                   /note="PPR 16"
FT   REPEAT          659..689
FT                   /note="PPR 17"
FT   REGION          694..769
FT                   /note="Type E motif"
FT   REGION          770..800
FT                   /note="Type E(+) motif"
FT   REGION          801..896
FT                   /note="Type DYW motif"
SQ   SEQUENCE   896 AA;  101155 MW;  A4D9C4DEF09287B6 CRC64;
     MSTVNHHCLL NFPHIPPSIP PNHRPKLLSS LSLYRKPERL FALSASLSLS PATIHECSSS
     SSSSSSSFDK EETEDIESVI DGFFYLLRLS AQYHDVEVTK AVHASFLKLR EEKTRLGNAL
     ISTYLKLGFP REAILVFVSL SSPTVVSYTA LISGFSRLNL EIEALKVFFR MRKAGLVQPN
     EYTFVAILTA CVRVSRFSLG IQIHGLIVKS GFLNSVFVSN SLMSLYDKDS GSSCDDVLKL
     FDEIPQRDVA SWNTVVSSLV KEGKSHKAFD LFYEMNRVEG FGVDSFTLST LLSSCTDSSV
     LLRGRELHGR AIRIGLMQEL SVNNALIGFY SKFWDMKKVE SLYEMMMAQD AVTFTEMITA
     YMSFGMVDSA VEIFANVTEK NTITYNALMA GFCRNGHGLK ALKLFTDMLQ RGVELTDFSL
     TSAVDACGLV SEKKVSEQIH GFCIKFGTAF NPCIQTALLD MCTRCERMAD AEEMFDQWPS
     NLDSSKATTS IIGGYARNGL PDKAVSLFHR TLCEQKLFLD EVSLTLILAV CGTLGFREMG
     YQIHCYALKA GYFSDISLGN SLISMYAKCC DSDDAIKIFN TMREHDVISW NSLISCYILQ
     RNGDEALALW SRMNEKEIKP DIITLTLVIS AFRYTESNKL SSCRDLFLSM KTIYDIEPTT
     EHYTAFVRVL GHWGLLEEAE DTINSMPVQP EVSVLRALLD SCRIHSNTSV AKRVAKLILS
     TKPETPSEYI LKSNIYSASG FWHRSEMIRE EMRERGYRKH PAKSWIIHEN KIHSFHARDT
     SHPQEKDIYR GLEILIMECL KVGYEPNTEY VLQEVDEFMK KSFLFHHSAK LAVTYGILSS
     NTRGKPVRVM KNVMLCGDCH EFFKYISVVV KREIVLRDSS GFHHFVNGKC SCRDLW