PP364_ARATH
ID PP364_ARATH Reviewed; 635 AA.
AC Q9LZ19;
DT 10-FEB-2009, integrated into UniProtKB/Swiss-Prot.
DT 10-FEB-2009, sequence version 2.
DT 03-AUG-2022, entry version 134.
DE RecName: Full=Pentatricopeptide repeat-containing protein At5g04780, mitochondrial;
DE Flags: Precursor;
GN Name=PCMP-H16; OrderedLocusNames=At5g04780; ORFNames=MUK11.10, T1E3_140;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=9501997; DOI=10.1093/dnares/4.6.401;
RA Nakamura Y., Sato S., Kaneko T., Kotani H., Asamizu E., Miyajima N.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. III. Sequence
RT features of the regions of 1,191,918 bp covered by seventeen physically
RT assigned P1 clones.";
RL DNA Res. 4:401-414(1997).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130714; DOI=10.1038/35048507;
RA Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E.,
RA Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M.,
RA Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K.,
RA Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M.,
RA Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L.,
RA O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D.,
RA Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M.,
RA Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L.,
RA Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B.,
RA Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P.,
RA Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M.,
RA Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D.,
RA Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A.,
RA Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I.,
RA Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T.,
RA Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A.,
RA McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U.,
RA Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W.,
RA Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M.,
RA Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S.,
RA Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G.,
RA Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W.,
RA Bevan M., Fransz P.F.;
RT "Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana.";
RL Nature 408:823-826(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP GENE FAMILY.
RX PubMed=10809006; DOI=10.1023/a:1006352315928;
RA Aubourg S., Boudet N., Kreis M., Lecharny A.;
RT "In Arabidopsis thaliana, 1% of the genome codes for a novel protein family
RT unique to plants.";
RL Plant Mol. Biol. 42:603-613(2000).
RN [5]
RP GENE FAMILY.
RX PubMed=15269332; DOI=10.1105/tpc.104.022236;
RA Lurin C., Andres C., Aubourg S., Bellaoui M., Bitton F., Bruyere C.,
RA Caboche M., Debast C., Gualberto J., Hoffmann B., Lecharny A., Le Ret M.,
RA Martin-Magniette M.-L., Mireau H., Peeters N., Renou J.-P., Szurek B.,
RA Taconnat L., Small I.;
RT "Genome-wide analysis of Arabidopsis pentatricopeptide repeat proteins
RT reveals their essential role in organelle biogenesis.";
RL Plant Cell 16:2089-2103(2004).
RN [6]
RP IDENTIFICATION BY MASS SPECTROMETRY, AND CLEAVAGE OF TRANSIT PEPTIDE AFTER
RP ILE-38.
RX PubMed=25732537; DOI=10.1093/jxb/erv064;
RA Carrie C., Venne A.S., Zahedi R.P., Soll J.;
RT "Identification of cleavage sites and substrate proteins for two
RT mitochondrial intermediate peptidases in Arabidopsis thaliana.";
RL J. Exp. Bot. 66:2691-2708(2015).
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000305|PubMed:25732537}.
CC -!- SIMILARITY: Belongs to the PPR family. PCMP-H subfamily. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAB08982.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=CAB86020.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC -!- WEB RESOURCE: Name=Pentatricopeptide repeat proteins;
CC URL="https://ppr.plantenergy.uwa.edu.au";
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AB008271; BAB08982.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AL162972; CAB86020.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002688; AED90783.1; -; Genomic_DNA.
DR PIR; T48474; T48474.
DR RefSeq; NP_196098.3; NM_120560.4.
DR AlphaFoldDB; Q9LZ19; -.
DR SMR; Q9LZ19; -.
DR STRING; 3702.AT5G04780.1; -.
DR PaxDb; Q9LZ19; -.
DR PRIDE; Q9LZ19; -.
DR ProteomicsDB; 249254; -.
DR EnsemblPlants; AT5G04780.1; AT5G04780.1; AT5G04780.
DR GeneID; 830356; -.
DR Gramene; AT5G04780.1; AT5G04780.1; AT5G04780.
DR KEGG; ath:AT5G04780; -.
DR Araport; AT5G04780; -.
DR TAIR; locus:2175498; AT5G04780.
DR eggNOG; KOG4197; Eukaryota.
DR HOGENOM; CLU_002706_37_2_1; -.
DR InParanoid; Q9LZ19; -.
DR OMA; QLCAKTR; -.
DR OrthoDB; 1344243at2759; -.
DR PhylomeDB; Q9LZ19; -.
DR PRO; PR:Q9LZ19; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9LZ19; baseline and differential.
DR GO; GO:0043231; C:intracellular membrane-bounded organelle; IBA:GO_Central.
DR GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0009451; P:RNA modification; IBA:GO_Central.
DR Gene3D; 1.25.40.10; -; 3.
DR InterPro; IPR032867; DYW_dom.
DR InterPro; IPR002885; Pentatricopeptide_repeat.
DR InterPro; IPR045215; PPR_prot_plant.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR PANTHER; PTHR24015; PTHR24015; 1.
DR Pfam; PF14432; DYW_deaminase; 1.
DR Pfam; PF01535; PPR; 3.
DR Pfam; PF12854; PPR_1; 1.
DR Pfam; PF13041; PPR_2; 2.
DR SUPFAM; SSF48452; SSF48452; 2.
DR TIGRFAMs; TIGR00756; PPR; 6.
DR PROSITE; PS51375; PPR; 9.
PE 2: Evidence at transcript level;
KW Mitochondrion; Reference proteome; Repeat; Transit peptide.
FT TRANSIT 1..38
FT /note="Mitochondrion"
FT /evidence="ECO:0000269|PubMed:25732537"
FT CHAIN 39..635
FT /note="Pentatricopeptide repeat-containing protein
FT At5g04780, mitochondrial"
FT /id="PRO_0000363501"
FT REPEAT 60..94
FT /note="PPR 1"
FT REPEAT 95..125
FT /note="PPR 2"
FT REPEAT 126..160
FT /note="PPR 3"
FT REPEAT 161..195
FT /note="PPR 4"
FT REPEAT 196..226
FT /note="PPR 5"
FT REPEAT 227..261
FT /note="PPR 6"
FT REPEAT 262..296
FT /note="PPR 7"
FT REPEAT 297..327
FT /note="PPR 8"
FT REPEAT 328..362
FT /note="PPR 9"
FT REPEAT 363..393
FT /note="PPR 10"
FT REPEAT 399..429
FT /note="PPR 11"
FT REGION 434..509
FT /note="Type E motif"
FT REGION 510..540
FT /note="Type E(+) motif"
FT REGION 541..635
FT /note="Type DYW motif"
SQ SEQUENCE 635 AA; 71725 MW; B9EFFE2B7F436892 CRC64;
MLSPSLPRMN ILGFTVNFLI RCKVLPRRSN TSSLSRNISV LASYDQEEVS PGRYSNEFSN
RNLVHEILQL CARNGAVMEA KACHGKIIRI DLEGDVTLLN VLINAYSKCG FVELARQVFD
GMLERSLVSW NTMIGLYTRN RMESEALDIF LEMRNEGFKF SEFTISSVLS ACGVNCDALE
CKKLHCLSVK TCIDLNLYVG TALLDLYAKC GMIKDAVQVF ESMQDKSSVT WSSMVAGYVQ
NKNYEEALLL YRRAQRMSLE QNQFTLSSVI CACSNLAALI EGKQMHAVIC KSGFGSNVFV
ASSAVDMYAK CGSLRESYII FSEVQEKNLE LWNTIISGFA KHARPKEVMI LFEKMQQDGM
HPNEVTFSSL LSVCGHTGLV EEGRRFFKLM RTTYGLSPNV VHYSCMVDIL GRAGLLSEAY
ELIKSIPFDP TASIWGSLLA SCRVYKNLEL AEVAAEKLFE LEPENAGNHV LLSNIYAANK
QWEEIAKSRK LLRDCDVKKV RGKSWIDIKD KVHTFSVGES GHPRIREICS TLDNLVIKFR
KFGYKPSVEH ELHDVEIGKK EELLMQHSEK LALVFGLMCL PESSPVRIMK NLRICVDCHE
FMKAASMATR RFIIVRDVNR FHHFSDGHCS CGDFW
