PP365_ARATH
ID PP365_ARATH Reviewed; 952 AA.
AC Q0WMY5; Q944Q3; Q9FMC9; Q9LZ16;
DT 10-FEB-2009, integrated into UniProtKB/Swiss-Prot.
DT 05-SEP-2006, sequence version 1.
DT 03-AUG-2022, entry version 98.
DE RecName: Full=Pentatricopeptide repeat-containing protein At5g04810, chloroplastic;
DE AltName: Full=Maize PPR4 homolog;
DE Short=AtPPR4;
DE Flags: Precursor;
GN Name=PPR4; OrderedLocusNames=At5g04810; ORFNames=MUK11.13, T1E3_170;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=9501997; DOI=10.1093/dnares/4.6.401;
RA Nakamura Y., Sato S., Kaneko T., Kotani H., Asamizu E., Miyajima N.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. III. Sequence
RT features of the regions of 1,191,918 bp covered by seventeen physically
RT assigned P1 clones.";
RL DNA Res. 4:401-414(1997).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] OF 1-883.
RC STRAIN=cv. Columbia;
RX PubMed=11130714; DOI=10.1038/35048507;
RA Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E.,
RA Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M.,
RA Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K.,
RA Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M.,
RA Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L.,
RA O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D.,
RA Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M.,
RA Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L.,
RA Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B.,
RA Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P.,
RA Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M.,
RA Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D.,
RA Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A.,
RA Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I.,
RA Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T.,
RA Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A.,
RA McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U.,
RA Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W.,
RA Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M.,
RA Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S.,
RA Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G.,
RA Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W.,
RA Bevan M., Fransz P.F.;
RT "Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana.";
RL Nature 408:823-826(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP GENE FAMILY.
RX PubMed=15269332; DOI=10.1105/tpc.104.022236;
RA Lurin C., Andres C., Aubourg S., Bellaoui M., Bitton F., Bruyere C.,
RA Caboche M., Debast C., Gualberto J., Hoffmann B., Lecharny A., Le Ret M.,
RA Martin-Magniette M.-L., Mireau H., Peeters N., Renou J.-P., Szurek B.,
RA Taconnat L., Small I.;
RT "Genome-wide analysis of Arabidopsis pentatricopeptide repeat proteins
RT reveals their essential role in organelle biogenesis.";
RL Plant Cell 16:2089-2103(2004).
RN [7]
RP FUNCTION.
RX PubMed=17041147; DOI=10.1105/tpc.106.046110;
RA Schmitz-Linneweber C., Williams-Carrier R.E., Williams-Voelker P.M.,
RA Kroeger T.S., Vichas A., Barkan A.;
RT "A pentatricopeptide repeat protein facilitates the trans-splicing of the
RT maize chloroplast rps12 pre-mRNA.";
RL Plant Cell 18:2650-2663(2006).
RN [8]
RP IDENTIFICATION BY MASS SPECTROMETRY, AND SUBCELLULAR LOCATION [LARGE SCALE
RP ANALYSIS].
RX PubMed=18431481; DOI=10.1371/journal.pone.0001994;
RA Zybailov B., Rutschow H., Friso G., Rudella A., Emanuelsson O., Sun Q.,
RA van Wijk K.J.;
RT "Sorting signals, N-terminal modifications and abundance of the chloroplast
RT proteome.";
RL PLoS ONE 3:E1994-E1994(2008).
CC -!- FUNCTION: May play a role in the plastid ribosome biogenesis.
CC {ECO:0000269|PubMed:17041147}.
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast
CC {ECO:0000269|PubMed:18431481}.
CC -!- SIMILARITY: Belongs to the PPR family. P subfamily. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAL11611.1; Type=Frameshift; Evidence={ECO:0000305};
CC Sequence=BAB08985.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=CAB86023.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC -!- WEB RESOURCE: Name=Pentatricopeptide repeat proteins;
CC URL="https://ppr.plantenergy.uwa.edu.au";
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DR EMBL; AB008271; BAB08985.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AL162972; CAB86023.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002688; AED90789.1; -; Genomic_DNA.
DR EMBL; AF424618; AAL11611.1; ALT_FRAME; mRNA.
DR EMBL; AK229672; BAF01515.1; -; mRNA.
DR PIR; T48477; T48477.
DR RefSeq; NP_568141.2; NM_120563.5.
DR AlphaFoldDB; Q0WMY5; -.
DR SMR; Q0WMY5; -.
DR STRING; 3702.AT5G04810.1; -.
DR PaxDb; Q0WMY5; -.
DR PRIDE; Q0WMY5; -.
DR ProteomicsDB; 249255; -.
DR EnsemblPlants; AT5G04810.1; AT5G04810.1; AT5G04810.
DR GeneID; 830360; -.
DR Gramene; AT5G04810.1; AT5G04810.1; AT5G04810.
DR KEGG; ath:AT5G04810; -.
DR Araport; AT5G04810; -.
DR TAIR; locus:2175443; AT5G04810.
DR eggNOG; KOG4197; Eukaryota.
DR HOGENOM; CLU_011727_0_0_1; -.
DR InParanoid; Q0WMY5; -.
DR OrthoDB; 1344243at2759; -.
DR PhylomeDB; Q0WMY5; -.
DR PRO; PR:Q0WMY5; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q0WMY5; baseline and differential.
DR Genevisible; Q0WMY5; AT.
DR GO; GO:0009507; C:chloroplast; HDA:TAIR.
DR GO; GO:0003729; F:mRNA binding; IDA:TAIR.
DR GO; GO:0009880; P:embryonic pattern specification; IDA:TAIR.
DR GO; GO:0048366; P:leaf development; IDA:TAIR.
DR GO; GO:0008380; P:RNA splicing; IMP:TAIR.
DR Gene3D; 1.25.40.10; -; 7.
DR Gene3D; 3.30.70.330; -; 1.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR002885; Pentatricopeptide_repeat.
DR InterPro; IPR033443; PPR_long.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR Pfam; PF01535; PPR; 2.
DR Pfam; PF12854; PPR_1; 1.
DR Pfam; PF13041; PPR_2; 3.
DR Pfam; PF13812; PPR_3; 2.
DR Pfam; PF17177; PPR_long; 1.
DR Pfam; PF00076; RRM_1; 1.
DR SMART; SM00360; RRM; 1.
DR SUPFAM; SSF54928; SSF54928; 1.
DR TIGRFAMs; TIGR00756; PPR; 14.
DR PROSITE; PS51375; PPR; 15.
DR PROSITE; PS50102; RRM; 1.
PE 1: Evidence at protein level;
KW Chloroplast; Plastid; Reference proteome; Repeat; RNA-binding;
KW Transit peptide.
FT TRANSIT 1..60
FT /note="Chloroplast"
FT /evidence="ECO:0000255"
FT CHAIN 61..952
FT /note="Pentatricopeptide repeat-containing protein
FT At5g04810, chloroplastic"
FT /id="PRO_0000363502"
FT DOMAIN 167..238
FT /note="RRM"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT REPEAT 308..342
FT /note="PPR 1"
FT REPEAT 343..377
FT /note="PPR 2"
FT REPEAT 378..412
FT /note="PPR 3"
FT REPEAT 413..447
FT /note="PPR 4"
FT REPEAT 448..482
FT /note="PPR 5"
FT REPEAT 483..517
FT /note="PPR 6"
FT REPEAT 518..552
FT /note="PPR 7"
FT REPEAT 553..587
FT /note="PPR 8"
FT REPEAT 588..622
FT /note="PPR 9"
FT REPEAT 623..657
FT /note="PPR 10"
FT REPEAT 658..692
FT /note="PPR 11"
FT REPEAT 693..727
FT /note="PPR 12"
FT REPEAT 728..762
FT /note="PPR 13"
FT REPEAT 763..797
FT /note="PPR 14"
FT REPEAT 798..832
FT /note="PPR 15"
FT REGION 30..95
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 115..163
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 259..281
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 918..952
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 120..135
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 137..160
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 922..943
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 952 AA; 106740 MW; 6D59E546E657B74D CRC64;
MDNGGSVLSL SAPHFPYSAT ILRRHSPVAS ISFSLKQPPP QPPEPPESPP DLRRPEKSIG
SSSSSSSPSP IPSPKTPLKI NPLKGLTNRS SVSPLVQSEV SSKVSSFGSS LASKLRLSSK
LSPPPPPPPP PPVEETTQFR DEFRSDTKPP EEETRNPQQE FRQEGKIFVG NLPTWIKKPE
FEEFFRQFGP IENVILIKGH HEVEKNAGFG FIIYAAEKSA MKAVEFDGVE FHGRILTVKL
DDGKRLKTKA EQRVRWVEEG EEDTKMSNKS SWHQEREGSR KSLQRILDTN GDNWQAVISA
FEKISKPSRT EFGLMVKFYG RRGDMHRARE TFERMRARGI TPTSRIYTSL IHAYAVGRDM
DEALSCVRKM KEEGIEMSLV TYSVIVGGFS KAGHAEAADY WFDEAKRIHK TLNASIYGKI
IYAHCQTCNM ERAEALVREM EEEGIDAPIA IYHTMMDGYT MVADEKKGLV VFKRLKECGF
TPTVVTYGCL INLYTKVGKI SKALEVSRVM KEEGVKHNLK TYSMMINGFV KLKDWANAFA
VFEDMVKEGM KPDVILYNNI ISAFCGMGNM DRAIQTVKEM QKLRHRPTTR TFMPIIHGYA
KSGDMRRSLE VFDMMRRCGC VPTVHTFNGL INGLVEKRQM EKAVEILDEM TLAGVSANEH
TYTKIMQGYA SVGDTGKAFE YFTRLQNEGL DVDIFTYEAL LKACCKSGRM QSALAVTKEM
SARNIPRNSF VYNILIDGWA RRGDVWEAAD LIQQMKKEGV KPDIHTYTSF ISACSKAGDM
NRATQTIEEM EALGVKPNIK TYTTLIKGWA RASLPEKALS CYEEMKAMGI KPDKAVYHCL
LTSLLSRASI AEAYIYSGVM TICKEMVEAG LIVDMGTAVH WSKCLCKIEA SGGELTETLQ
KTFPPDWSSH HHHHGFLDQV SDVDSDEDDV DGEDGEDDED VNSVSDLLSP YK
