ID   PP372_ARATH             Reviewed;         409 AA.
AC   Q94B59; Q8LCU1; Q9FY70;
DT   10-FEB-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2001, sequence version 1.
DT   25-MAY-2022, entry version 105.
DE   RecName: Full=Pentatricopeptide repeat-containing protein At5g09450, mitochondrial;
DE   Flags: Precursor;
GN   OrderedLocusNames=At5g09450; ORFNames=T5E8_250;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=11130714; DOI=10.1038/35048507;
RA   Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E.,
RA   Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M.,
RA   Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K.,
RA   Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M.,
RA   Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L.,
RA   O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D.,
RA   Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M.,
RA   Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L.,
RA   Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B.,
RA   Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P.,
RA   Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M.,
RA   Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D.,
RA   Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A.,
RA   Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I.,
RA   Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T.,
RA   Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A.,
RA   McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U.,
RA   Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W.,
RA   Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M.,
RA   Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S.,
RA   Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G.,
RA   Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W.,
RA   Bevan M., Fransz P.F.;
RT   "Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana.";
RL   Nature 408:823-826(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=14593172; DOI=10.1126/science.1088305;
RA   Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA   Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA   Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA   Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA   Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA   Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA   Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA   Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA   Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA   Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA   Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA   Ecker J.R.;
RT   "Empirical analysis of transcriptional activity in the Arabidopsis
RT   genome.";
RL   Science 302:842-846(2003).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA   Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA   Feldmann K.A.;
RT   "Full-length cDNA from Arabidopsis thaliana.";
RL   Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN   [5]
RP   GENE FAMILY.
RX   PubMed=15269332; DOI=10.1105/tpc.104.022236;
RA   Lurin C., Andres C., Aubourg S., Bellaoui M., Bitton F., Bruyere C.,
RA   Caboche M., Debast C., Gualberto J., Hoffmann B., Lecharny A., Le Ret M.,
RA   Martin-Magniette M.-L., Mireau H., Peeters N., Renou J.-P., Szurek B.,
RA   Taconnat L., Small I.;
RT   "Genome-wide analysis of Arabidopsis pentatricopeptide repeat proteins
RT   reveals their essential role in organelle biogenesis.";
RL   Plant Cell 16:2089-2103(2004).
RN   [6]
RP   IDENTIFICATION BY MASS SPECTROMETRY, AND CLEAVAGE OF TRANSIT PEPTIDE AFTER
RP   ASN-38.
RX   PubMed=25732537; DOI=10.1093/jxb/erv064;
RA   Carrie C., Venne A.S., Zahedi R.P., Soll J.;
RT   "Identification of cleavage sites and substrate proteins for two
RT   mitochondrial intermediate peptidases in Arabidopsis thaliana.";
RL   J. Exp. Bot. 66:2691-2708(2015).
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000305|PubMed:25732537}.
CC   -!- SIMILARITY: Belongs to the PPR family. P subfamily. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAC05471.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC   -!- WEB RESOURCE: Name=Pentatricopeptide repeat proteins;
CC       URL="https://ppr.plantenergy.uwa.edu.au";
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DR   EMBL; AL391712; CAC05471.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; CP002688; AED91395.1; -; Genomic_DNA.
DR   EMBL; AY042834; AAK68774.1; -; mRNA.
DR   EMBL; BT002562; AAO00922.1; -; mRNA.
DR   EMBL; AY086405; AAM64472.1; -; mRNA.
DR   RefSeq; NP_568214.1; NM_120982.3.
DR   AlphaFoldDB; Q94B59; -.
DR   SMR; Q94B59; -.
DR   BioGRID; 16082; 6.
DR   IntAct; Q94B59; 6.
DR   STRING; 3702.AT5G09450.1; -.
DR   PaxDb; Q94B59; -.
DR   PRIDE; Q94B59; -.
DR   ProteomicsDB; 249001; -.
DR   EnsemblPlants; AT5G09450.1; AT5G09450.1; AT5G09450.
DR   GeneID; 830804; -.
DR   Gramene; AT5G09450.1; AT5G09450.1; AT5G09450.
DR   KEGG; ath:AT5G09450; -.
DR   Araport; AT5G09450; -.
DR   TAIR; locus:2184807; AT5G09450.
DR   eggNOG; KOG4197; Eukaryota.
DR   HOGENOM; CLU_019802_0_0_1; -.
DR   InParanoid; Q94B59; -.
DR   OMA; SSRSYIC; -.
DR   OrthoDB; 1344243at2759; -.
DR   PhylomeDB; Q94B59; -.
DR   PRO; PR:Q94B59; -.
DR   Proteomes; UP000006548; Chromosome 5.
DR   ExpressionAtlas; Q94B59; baseline and differential.
DR   Genevisible; Q94B59; AT.
DR   GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR   Gene3D; 1.25.40.10; -; 1.
DR   InterPro; IPR002885; Pentatricopeptide_repeat.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   Pfam; PF01535; PPR; 2.
DR   Pfam; PF13041; PPR_2; 1.
DR   TIGRFAMs; TIGR00756; PPR; 2.
DR   PROSITE; PS51375; PPR; 4.
PE   1: Evidence at protein level;
KW   Mitochondrion; Reference proteome; Repeat; Transit peptide.
FT   TRANSIT         1..38
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000269|PubMed:25732537"
FT   CHAIN           39..409
FT                   /note="Pentatricopeptide repeat-containing protein
FT                   At5g09450, mitochondrial"
FT                   /id="PRO_0000363509"
FT   REPEAT          155..189
FT                   /note="PPR 1"
FT   REPEAT          191..225
FT                   /note="PPR 2"
FT   REPEAT          226..256
FT                   /note="PPR 3"
FT   REPEAT          262..296
FT                   /note="PPR 4"
FT   REPEAT          298..332
FT                   /note="PPR 5"
FT   REPEAT          333..367
FT                   /note="PPR 6"
FT   CONFLICT        150
FT                   /note="D -> H (in Ref. 4; AAM64472)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   409 AA;  46809 MW;  8C40FF3B52F02194 CRC64;
     MATRSLFHSL RCRLTNNGVL GSNFIRNAES SRFSKSYNAD AAIGNSLVEE SEEKDDLKSR
     IFRLRLPKRS ATTVLEKWIG EGNQMTINEL REISKELRRT RRYKHALEVT EWMVQHEESK
     ISDADYASRI DLISKVFGID AAERYFEGLD IDSKTAETYT SLLHAYAASK QTERAEALFK
     RIIESDSLTF GAITYNEMMT LYMSVGQVEK VPEVIEVLKQ KKVSPDIFTY NLWLSSCAAT
     FNIDELRKIL EEMRHDASSN EGWVRYIDLT SIYINSSRVT NAESTLPVEA EKSISQREWI
     TYDFLMILHT GLGNKVMIDQ IWKSLRNTNQ ILSSRSYICV LSSYLMLGHL REAEEIIHQW
     KESKTTEFDA SACLRILNAF RDVGLEGIAS GFHLILVHNK CSLENEGSS