ID   PP395_ARATH             Reviewed;         831 AA.
AC   Q8S9D1; Q84VQ2; Q8S9D2;
DT   10-FEB-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2002, sequence version 1.
DT   03-AUG-2022, entry version 134.
DE   RecName: Full=Pentatricopeptide repeat-containing protein At5g21222;
DE   AltName: Full=SNF1-like protein kinase AtC401;
GN   Name=ATC401; OrderedLocusNames=At5g21222; ORFNames=F13M11;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=cv. Columbia; TISSUE=Seedling;
RX   PubMed=9536066; DOI=10.1104/pp.116.4.1479;
RA   Sage-Ono K., Ono M., Harada H., Kamada H.;
RT   "Accumulation of a clock-regulated transcript during flower-inductive
RT   darkness in Pharbitis nil.";
RL   Plant Physiol. 116:1479-1485(1998).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=15087121; DOI=10.1016/j.gene.2003.11.012;
RA   Oguchi T., Sage-Ono K., Kamada H., Ono M.;
RT   "Genomic structure of a novel Arabidopsis clock-controlled gene, AtC401,
RT   which encodes a pentatricopeptide repeat protein.";
RL   Gene 330:29-37(2004).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=11130714; DOI=10.1038/35048507;
RA   Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E.,
RA   Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M.,
RA   Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K.,
RA   Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M.,
RA   Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L.,
RA   O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D.,
RA   Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M.,
RA   Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L.,
RA   Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B.,
RA   Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P.,
RA   Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M.,
RA   Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D.,
RA   Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A.,
RA   Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I.,
RA   Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T.,
RA   Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A.,
RA   McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U.,
RA   Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W.,
RA   Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M.,
RA   Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S.,
RA   Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G.,
RA   Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W.,
RA   Bevan M., Fransz P.F.;
RT   "Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana.";
RL   Nature 408:823-826(2000).
RN   [4]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [5]
RP   GENE FAMILY.
RX   PubMed=15269332; DOI=10.1105/tpc.104.022236;
RA   Lurin C., Andres C., Aubourg S., Bellaoui M., Bitton F., Bruyere C.,
RA   Caboche M., Debast C., Gualberto J., Hoffmann B., Lecharny A., Le Ret M.,
RA   Martin-Magniette M.-L., Mireau H., Peeters N., Renou J.-P., Szurek B.,
RA   Taconnat L., Small I.;
RT   "Genome-wide analysis of Arabidopsis pentatricopeptide repeat proteins
RT   reveals their essential role in organelle biogenesis.";
RL   Plant Cell 16:2089-2103(2004).
CC   -!- DOMAIN: The protein kinase domain is predicted to be catalytically
CC       inactive.
CC   -!- SIMILARITY: In the N-terminal section; belongs to the protein kinase
CC       superfamily. Ser/Thr protein kinase family. {ECO:0000305}.
CC   -!- SIMILARITY: In the C-terminal section; belongs to the PPR family. P
CC       subfamily. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAO73889.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC   -!- WEB RESOURCE: Name=Pentatricopeptide repeat proteins;
CC       URL="https://ppr.plantenergy.uwa.edu.au";
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DR   EMBL; AB050965; BAB85657.1; -; mRNA.
DR   EMBL; AB052663; BAB85674.1; -; Genomic_DNA.
DR   EMBL; AC140977; AAO73889.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; CP002688; AED92946.1; -; Genomic_DNA.
DR   EMBL; CP002688; ANM68257.1; -; Genomic_DNA.
DR   EMBL; CP002688; ANM68258.1; -; Genomic_DNA.
DR   EMBL; CP002688; ANM68259.1; -; Genomic_DNA.
DR   RefSeq; NP_001330026.1; NM_001343701.1.
DR   RefSeq; NP_001330027.1; NM_001343700.1.
DR   RefSeq; NP_001330028.1; NM_001343702.1.
DR   RefSeq; NP_850859.2; NM_180528.4.
DR   AlphaFoldDB; Q8S9D1; -.
DR   SMR; Q8S9D1; -.
DR   STRING; 3702.AT5G21222.1; -.
DR   PaxDb; Q8S9D1; -.
DR   PRIDE; Q8S9D1; -.
DR   ProteomicsDB; 249276; -.
DR   EnsemblPlants; AT5G21222.1; AT5G21222.1; AT5G21222.
DR   EnsemblPlants; AT5G21222.2; AT5G21222.2; AT5G21222.
DR   EnsemblPlants; AT5G21222.3; AT5G21222.3; AT5G21222.
DR   EnsemblPlants; AT5G21222.4; AT5G21222.4; AT5G21222.
DR   GeneID; 832244; -.
DR   Gramene; AT5G21222.1; AT5G21222.1; AT5G21222.
DR   Gramene; AT5G21222.2; AT5G21222.2; AT5G21222.
DR   Gramene; AT5G21222.3; AT5G21222.3; AT5G21222.
DR   Gramene; AT5G21222.4; AT5G21222.4; AT5G21222.
DR   KEGG; ath:AT5G21222; -.
DR   Araport; AT5G21222; -.
DR   TAIR; locus:1005716169; AT5G21222.
DR   eggNOG; KOG0583; Eukaryota.
DR   eggNOG; KOG4197; Eukaryota.
DR   HOGENOM; CLU_017336_0_0_1; -.
DR   OMA; CIKSQFG; -.
DR   OrthoDB; 1344243at2759; -.
DR   PhylomeDB; Q8S9D1; -.
DR   PRO; PR:Q8S9D1; -.
DR   Proteomes; UP000006548; Chromosome 5.
DR   ExpressionAtlas; Q8S9D1; baseline and differential.
DR   GO; GO:0009536; C:plastid; HDA:TAIR.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0003729; F:mRNA binding; IDA:TAIR.
DR   GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR   GO; GO:0006468; P:protein phosphorylation; IEA:InterPro.
DR   Gene3D; 1.25.40.10; -; 4.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   InterPro; IPR002885; Pentatricopeptide_repeat.
DR   InterPro; IPR000719; Prot_kinase_dom.
DR   InterPro; IPR008271; Ser/Thr_kinase_AS.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   Pfam; PF00069; Pkinase; 1.
DR   Pfam; PF01535; PPR; 1.
DR   Pfam; PF13041; PPR_2; 3.
DR   Pfam; PF13812; PPR_3; 2.
DR   SMART; SM00220; S_TKc; 1.
DR   SUPFAM; SSF56112; SSF56112; 1.
DR   TIGRFAMs; TIGR00756; PPR; 10.
DR   PROSITE; PS51375; PPR; 12.
DR   PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR   PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome; Repeat.
FT   CHAIN           1..831
FT                   /note="Pentatricopeptide repeat-containing protein
FT                   At5g21222"
FT                   /id="PRO_0000363532"
FT   DOMAIN          13..268
FT                   /note="Protein kinase"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00159"
FT   REPEAT          318..352
FT                   /note="PPR 1"
FT   REPEAT          353..387
FT                   /note="PPR 2"
FT   REPEAT          388..422
FT                   /note="PPR 3"
FT   REPEAT          423..457
FT                   /note="PPR 4"
FT   REPEAT          459..493
FT                   /note="PPR 5"
FT   REPEAT          494..529
FT                   /note="PPR 6"
FT   REPEAT          530..564
FT                   /note="PPR 7"
FT   REPEAT          565..599
FT                   /note="PPR 8"
FT   REPEAT          600..634
FT                   /note="PPR 9"
FT   REPEAT          635..669
FT                   /note="PPR 10"
FT   REPEAT          670..705
FT                   /note="PPR 11"
FT   REPEAT          706..740
FT                   /note="PPR 12"
FT   CONFLICT        656
FT                   /note="E -> K (in Ref. 1; BAB85657)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   831 AA;  93143 MW;  5B8F3EF03232632A CRC64;
     MSEPKVRRWV GKYEVGRLIG ECNFGKLRSA VDTETGDPVA LMILDKDKVL KHKMAEQIKR
     EISIMKLINH PNVVQLYEVL ASKAKIYIVL EFISGGKLFD KIKNDGRMNE DEAQRYFQQL
     INAVDYCHSR GVYHRDLKPE NLLLDAQENL KVAEFGLIAL SQQAGGDGLR HTACGNPDYA
     APEVLNDQGY DGAKADLWSC GVILFVLLAG YLPFEDSSLT TLYKKISSAD FSCPPWLSSG
     VKNLIVRILD PNPMTRITIP EILEDVWFKK DYKPAVFEEK KEANLADVEA VFKDSEEGRV
     QLRSFPCVIC SGGTTCGDVR SRTKLMNGLI ERGRPQEAHS IFNTLIEEGH KPSLITYTTL
     VTALTRQKHF HSLLSLISKV EKNGLKPDTI LFNAIINASS ESGNLDQAMK IFEKMKESGC
     KPTASTFNTL IKGYGKIGKL EESSRLLDMM LRDEMLQPND RTCNILVQAW CNQRKIEEAW
     NIVYKMQSYG VKPDVVTFNT LAKAYARIGS TCTAEDMIIP RMLHNKVKPN VRTCGTIVNG
     YCEEGKMEEA LRFFYRMKEL GVHPNLFVFN SLIKGFLNIN DMDGVGEVVD LMEEFGVKPD
     VVTFSTLMNA WSSVGDMKRC EEIYTDMLEG GIDPDIHAFS ILAKGYARAG EPEKAEQILN
     QMRKFGVRPN VVIYTQIISG WCSAGEMKKA MQVYKKMCGI VGLSPNLTTY ETLIWGFGEA
     KQPWKAEELL KDMEGKNVVP TRKTMQLIAD GWKSIGVSNS NDANTLGSSF STSSKLNIPN
     NIASSRSPLF LKGMPEKPKL CIKSQFGLRQ TLLVVLCRDQ IGEAGRFCKF M