PP413_ARATH
ID PP413_ARATH Reviewed; 709 AA.
AC Q8L844; Q9FGZ8;
DT 10-FEB-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2002, sequence version 1.
DT 03-AUG-2022, entry version 115.
DE RecName: Full=Pentatricopeptide repeat-containing protein At5g42310, chloroplastic {ECO:0000305};
DE AltName: Full=Protein CRP1 homolog {ECO:0000303|PubMed:28261232};
DE Short=AtCRP1 {ECO:0000303|PubMed:28261232};
DE Flags: Precursor;
GN Name=CRP1 {ECO:0000303|PubMed:28261232};
GN OrderedLocusNames=At5g42310 {ECO:0000312|Araport:AT5G42310};
GN ORFNames=K5J14.11 {ECO:0000312|EMBL:BAB10204.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10718197; DOI=10.1093/dnares/7.1.31;
RA Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Kotani H.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. X. Sequence
RT features of the regions of 3,076,755 bp covered by sixty P1 and TAC
RT clones.";
RL DNA Res. 7:31-63(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP GENE FAMILY.
RX PubMed=15269332; DOI=10.1105/tpc.104.022236;
RA Lurin C., Andres C., Aubourg S., Bellaoui M., Bitton F., Bruyere C.,
RA Caboche M., Debast C., Gualberto J., Hoffmann B., Lecharny A., Le Ret M.,
RA Martin-Magniette M.-L., Mireau H., Peeters N., Renou J.-P., Szurek B.,
RA Taconnat L., Small I.;
RT "Genome-wide analysis of Arabidopsis pentatricopeptide repeat proteins
RT reveals their essential role in organelle biogenesis.";
RL Plant Cell 16:2089-2103(2004).
RN [5]
RP FUNCTION, SUBCELLULAR LOCATION, AND DISRUPTION PHENOTYPE.
RX PubMed=28261232; DOI=10.3389/fpls.2017.00163;
RA Ferrari R., Tadini L., Moratti F., Lehniger M.K., Costa A., Rossi F.,
RA Colombo M., Masiero S., Schmitz-Linneweber C., Pesaresi P.;
RT "CRP1 Protein: (dis)similarities between Arabidopsis thaliana and Zea
RT mays.";
RL Front. Plant Sci. 8:163-163(2017).
RN [6]
RP INTERACTION WITH PDE338, AND SUBCELLULAR LOCATION.
RX PubMed=30962391; DOI=10.1105/tpc.18.00946;
RA Jiang J., Chai X., Manavski N., Williams-Carrier R., He B., Brachmann A.,
RA Ji D., Ouyang M., Liu Y., Barkan A., Meurer J., Zhang L., Chi W.;
RT "An RNA Chaperone-Like Protein Plays Critical Roles in Chloroplast mRNA
RT Stability and Translation in Arabidopsis and Maize.";
RL Plant Cell 31:1308-1327(2019).
CC -!- FUNCTION: Required for chloroplast protein synthesis and accumulation
CC of subunits of the thylakoid protein complexes. Activates psaC and petA
CC translation by binding their 5'-UTRs. Required for the correct
CC processing of petB and petD mRNAs. Interacts with the petB and petD
CC intergenic region and is required for the generation of petB and petD
CC monocistronic RNAs. {ECO:0000269|PubMed:28261232}.
CC -!- SUBUNIT: Interacts with PDE338. {ECO:0000269|PubMed:30962391}.
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast stroma
CC {ECO:0000269|PubMed:28261232}. Plastid, chloroplast thylakoid
CC {ECO:0000269|PubMed:28261232}. Plastid, chloroplast
CC {ECO:0000269|PubMed:30962391}.
CC -!- DISRUPTION PHENOTYPE: Seedling lethality under normal growth
CC conditions. {ECO:0000269|PubMed:28261232}.
CC -!- SIMILARITY: Belongs to the PPR family. P subfamily. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAB10204.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC -!- WEB RESOURCE: Name=Pentatricopeptide repeat proteins;
CC URL="https://ppr.plantenergy.uwa.edu.au";
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DR EMBL; AB023032; BAB10204.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002688; AED94794.1; -; Genomic_DNA.
DR EMBL; AY120753; AAM53311.1; -; mRNA.
DR RefSeq; NP_199046.1; NM_123596.4.
DR AlphaFoldDB; Q8L844; -.
DR SMR; Q8L844; -.
DR STRING; 3702.AT5G42310.1; -.
DR PaxDb; Q8L844; -.
DR PRIDE; Q8L844; -.
DR ProteomicsDB; 249294; -.
DR EnsemblPlants; AT5G42310.1; AT5G42310.1; AT5G42310.
DR GeneID; 834236; -.
DR Gramene; AT5G42310.1; AT5G42310.1; AT5G42310.
DR KEGG; ath:AT5G42310; -.
DR Araport; AT5G42310; -.
DR TAIR; locus:2157607; AT5G42310.
DR eggNOG; KOG4197; Eukaryota.
DR HOGENOM; CLU_002706_49_12_1; -.
DR InParanoid; Q8L844; -.
DR OMA; HCKAGRH; -.
DR OrthoDB; 1344243at2759; -.
DR PhylomeDB; Q8L844; -.
DR PRO; PR:Q8L844; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q8L844; baseline and differential.
DR Genevisible; Q8L844; AT.
DR GO; GO:0009507; C:chloroplast; IDA:UniProtKB.
DR GO; GO:0042644; C:chloroplast nucleoid; IDA:TAIR.
DR GO; GO:0009570; C:chloroplast stroma; IDA:TAIR.
DR GO; GO:0009534; C:chloroplast thylakoid; IEA:UniProtKB-SubCell.
DR GO; GO:0042651; C:thylakoid membrane; IDA:TAIR.
DR GO; GO:0003729; F:mRNA binding; IDA:TAIR.
DR GO; GO:0003727; F:single-stranded RNA binding; IDA:TAIR.
DR GO; GO:0010239; P:chloroplast mRNA processing; IMP:TAIR.
DR GO; GO:0009658; P:chloroplast organization; IMP:TAIR.
DR GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.10; -; 4.
DR InterPro; IPR002885; Pentatricopeptide_repeat.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR Pfam; PF01535; PPR; 3.
DR Pfam; PF13041; PPR_2; 3.
DR Pfam; PF13812; PPR_3; 2.
DR TIGRFAMs; TIGR00756; PPR; 11.
DR PROSITE; PS51375; PPR; 14.
PE 1: Evidence at protein level;
KW Chloroplast; mRNA processing; Plastid; Reference proteome; Repeat;
KW RNA-binding; Thylakoid; Transit peptide; Translation regulation.
FT TRANSIT 1..54
FT /note="Chloroplast"
FT /evidence="ECO:0000255"
FT CHAIN 55..709
FT /note="Pentatricopeptide repeat-containing protein
FT At5g42310, chloroplastic"
FT /id="PRO_0000363550"
FT REPEAT 196..230
FT /note="PPR 1"
FT REPEAT 231..267
FT /note="PPR 2"
FT REPEAT 268..302
FT /note="PPR 3"
FT REPEAT 303..337
FT /note="PPR 4"
FT REPEAT 338..372
FT /note="PPR 5"
FT REPEAT 373..407
FT /note="PPR 6"
FT REPEAT 408..442
FT /note="PPR 7"
FT REPEAT 443..477
FT /note="PPR 8"
FT REPEAT 478..512
FT /note="PPR 9"
FT REPEAT 513..547
FT /note="PPR 10"
FT REPEAT 548..582
FT /note="PPR 11"
FT REPEAT 583..617
FT /note="PPR 12"
FT REPEAT 618..652
FT /note="PPR 13"
FT REPEAT 653..687
FT /note="PPR 14"
SQ SEQUENCE 709 AA; 80003 MW; F9617ED6411AC0E6 CRC64;
MLLLQQPPLV STRFHSLYFL THHHHHHHRF FQPPISAFSA TTSASLPSPS PSSSSSYFSS
WNGLDTNEEE DNEFSSEVHR RYDFSPLLKF LSRFGPVELA LDSESESEAS PESLNPVEFD
LVESYRAVPA PYWHSLIKSL TSSTSSLGLA YAVVSWLQKH NLCFSYELLY SILIHALGRS
EKLYEAFLLS QKQTLTPLTY NALIGACARN NDIEKALNLI AKMRQDGYQS DFVNYSLVIQ
SLTRSNKIDS VMLLRLYKEI ERDKLELDVQ LVNDIIMGFA KSGDPSKALQ LLGMAQATGL
SAKTATLVSI ISALADSGRT LEAEALFEEL RQSGIKPRTR AYNALLKGYV KTGPLKDAES
MVSEMEKRGV SPDEHTYSLL IDAYVNAGRW ESARIVLKEM EAGDVQPNSF VFSRLLAGFR
DRGEWQKTFQ VLKEMKSIGV KPDRQFYNVV IDTFGKFNCL DHAMTTFDRM LSEGIEPDRV
TWNTLIDCHC KHGRHIVAEE MFEAMERRGC LPCATTYNIM INSYGDQERW DDMKRLLGKM
KSQGILPNVV THTTLVDVYG KSGRFNDAIE CLEEMKSVGL KPSSTMYNAL INAYAQRGLS
EQAVNAFRVM TSDGLKPSLL ALNSLINAFG EDRRDAEAFA VLQYMKENGV KPDVVTYTTL
MKALIRVDKF QKVPVVYEEM IMSGCKPDRK ARSMLRSALR YMKQTLRAS
