ID   PP420_ARATH             Reviewed;         711 AA.
AC   Q9LS25;
DT   10-FEB-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   03-AUG-2022, entry version 112.
DE   RecName: Full=Pentatricopeptide repeat-containing protein At5g46580, chloroplastic;
DE   Flags: Precursor;
GN   OrderedLocusNames=At5g46580; ORFNames=F10E10.5;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RA   Kaneko T., Katoh T., Asamizu E., Sato S., Nakamura Y., Kotani H.,
RA   Tabata S.;
RT   "Structural analysis of Arabidopsis thaliana chromosome 5. XI.";
RL   Submitted (JUN-1999) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   GENE FAMILY.
RX   PubMed=15269332; DOI=10.1105/tpc.104.022236;
RA   Lurin C., Andres C., Aubourg S., Bellaoui M., Bitton F., Bruyere C.,
RA   Caboche M., Debast C., Gualberto J., Hoffmann B., Lecharny A., Le Ret M.,
RA   Martin-Magniette M.-L., Mireau H., Peeters N., Renou J.-P., Szurek B.,
RA   Taconnat L., Small I.;
RT   "Genome-wide analysis of Arabidopsis pentatricopeptide repeat proteins
RT   reveals their essential role in organelle biogenesis.";
RL   Plant Cell 16:2089-2103(2004).
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the PPR family. P subfamily. {ECO:0000305}.
CC   -!- WEB RESOURCE: Name=Pentatricopeptide repeat proteins;
CC       URL="https://ppr.plantenergy.uwa.edu.au";
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DR   EMBL; AB028605; BAA97529.1; -; Genomic_DNA.
DR   EMBL; CP002688; AED95400.1; -; Genomic_DNA.
DR   RefSeq; NP_199470.1; NM_124028.3.
DR   AlphaFoldDB; Q9LS25; -.
DR   SMR; Q9LS25; -.
DR   STRING; 3702.AT5G46580.1; -.
DR   iPTMnet; Q9LS25; -.
DR   PaxDb; Q9LS25; -.
DR   PRIDE; Q9LS25; -.
DR   ProteomicsDB; 249301; -.
DR   EnsemblPlants; AT5G46580.1; AT5G46580.1; AT5G46580.
DR   GeneID; 834701; -.
DR   Gramene; AT5G46580.1; AT5G46580.1; AT5G46580.
DR   KEGG; ath:AT5G46580; -.
DR   Araport; AT5G46580; -.
DR   TAIR; locus:2142320; AT5G46580.
DR   eggNOG; KOG4197; Eukaryota.
DR   HOGENOM; CLU_018319_0_0_1; -.
DR   InParanoid; Q9LS25; -.
DR   OMA; MKQSEHC; -.
DR   OrthoDB; 1344243at2759; -.
DR   PhylomeDB; Q9LS25; -.
DR   PRO; PR:Q9LS25; -.
DR   Proteomes; UP000006548; Chromosome 5.
DR   ExpressionAtlas; Q9LS25; baseline and differential.
DR   Genevisible; Q9LS25; AT.
DR   GO; GO:0009507; C:chloroplast; HDA:TAIR.
DR   GO; GO:0004530; F:deoxyribonuclease I activity; ISS:TAIR.
DR   GO; GO:0033902; F:rRNA endonuclease activity; ISS:TAIR.
DR   GO; GO:0042134; F:rRNA primary transcript binding; IDA:TAIR.
DR   GO; GO:1901259; P:chloroplast rRNA processing; IMP:TAIR.
DR   GO; GO:0042254; P:ribosome biogenesis; IMP:TAIR.
DR   Gene3D; 1.25.40.10; -; 3.
DR   InterPro; IPR002885; Pentatricopeptide_repeat.
DR   InterPro; IPR002625; Smr_dom.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   Pfam; PF13041; PPR_2; 2.
DR   Pfam; PF13812; PPR_3; 2.
DR   SUPFAM; SSF48452; SSF48452; 1.
DR   TIGRFAMs; TIGR00756; PPR; 7.
DR   PROSITE; PS51375; PPR; 10.
DR   PROSITE; PS50828; SMR; 1.
PE   2: Evidence at transcript level;
KW   Chloroplast; Plastid; Reference proteome; Repeat; Transit peptide.
FT   TRANSIT         1..43
FT                   /note="Chloroplast"
FT                   /evidence="ECO:0000255"
FT   CHAIN           44..711
FT                   /note="Pentatricopeptide repeat-containing protein
FT                   At5g46580, chloroplastic"
FT                   /id="PRO_0000363557"
FT   REPEAT          185..219
FT                   /note="PPR 1"
FT   REPEAT          220..254
FT                   /note="PPR 2"
FT   REPEAT          255..289
FT                   /note="PPR 3"
FT   REPEAT          290..324
FT                   /note="PPR 4"
FT   REPEAT          325..359
FT                   /note="PPR 5"
FT   REPEAT          360..394
FT                   /note="PPR 6"
FT   REPEAT          395..425
FT                   /note="PPR 7"
FT   REPEAT          431..465
FT                   /note="PPR 8"
FT   REPEAT          466..500
FT                   /note="PPR 9"
FT   REPEAT          501..535
FT                   /note="PPR 10"
FT   DOMAIN          614..696
FT                   /note="Smr"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00321"
SQ   SEQUENCE   711 AA;  80880 MW;  8F9B653655BFC6F1 CRC64;
     MATVLTTAID VCFNPQNSDT KKHSLFLKPS LFRQSRSRKL NISCSSLKQP KTLEEEPITT
     KTPSLSEQLK PLSATTLRQE QTQILSKPKS VWVNPTRPKR SVLSLQRQKR SAYSYNPQIK
     DLRAFALKLN SSIFTEKSEF LSLLDEIPHP PNRDNALLVL NSLREWQKTH TFFNWVKSKS
     LFPMETIFYN VTMKSLRFGR QFQLIEEMAL EMVKDGVELD NITYSTIITC AKRCNLYNKA
     IEWFERMYKT GLMPDEVTYS AILDVYSKSG KVEEVLSLYE RAVATGWKPD AIAFSVLGKM
     FGEAGDYDGI RYVLQEMKSM DVKPNVVVYN TLLEAMGRAG KPGLARSLFN EMLEAGLTPN
     EKTLTALVKI YGKARWARDA LQLWEEMKAK KWPMDFILYN TLLNMCADIG LEEEAERLFN
     DMKESVQCRP DNFSYTAMLN IYGSGGKAEK AMELFEEMLK AGVQVNVMGC TCLVQCLGKA
     KRIDDVVYVF DLSIKRGVKP DDRLCGCLLS VMALCESSED AEKVMACLER ANKKLVTFVN
     LIVDEKTEYE TVKEEFKLVI NATQVEARRP FCNCLIDICR GNNRHERAHE LLYLGTLFGL
     YPGLHNKTIK EWSLDVRSLS VGAAETALEE WMRTLANIIK RQEELPELFL AQTGTGTHRF
     SQGLANSFAL HLQQLSAPFR QSDRPGIFVA TKEDLVSWLE SKFPPLVTSQ A