ID   ATBP_DROPE              Reviewed;         373 AA.
AC   B4H4H5;
DT   07-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   07-JUL-2009, sequence version 2.
DT   25-MAY-2022, entry version 56.
DE   RecName: Full=AT-rich binding protein {ECO:0000250|UniProtKB:Q86P48};
GN   Name=ATbp {ECO:0000250|UniProtKB:Q86P48}; ORFNames=GL18332;
OS   Drosophila persimilis (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7234;
RN   [1] {ECO:0000312|EMBL:EDW32726.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MSH-3 / Tucson 14011-0111.49;
RX   PubMed=17994087; DOI=10.1038/nature06341;
RG   Drosophila 12 genomes consortium;
RT   "Evolution of genes and genomes on the Drosophila phylogeny.";
RL   Nature 450:203-218(2007).
CC   -!- FUNCTION: May be a transcription factor for genes having (A+T)
CC       stretches in their promoter and/or enhancer regions. Binds to AT rich
CC       DNA (By similarity). {ECO:0000250|UniProtKB:Q86P48}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q86P48}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=EDW32726.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; CH479209; EDW32726.1; ALT_SEQ; Genomic_DNA.
DR   RefSeq; XP_002025830.1; XM_002025794.1.
DR   AlphaFoldDB; B4H4H5; -.
DR   SMR; B4H4H5; -.
DR   STRING; 7234.FBpp0182439; -.
DR   EnsemblMetazoa; FBtr0183947; FBpp0182439; FBgn0155933.
DR   GeneID; 6600715; -.
DR   KEGG; dpe:6600715; -.
DR   eggNOG; KOG1721; Eukaryota.
DR   Proteomes; UP000008744; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; ISS:UniProtKB.
DR   InterPro; IPR036236; Znf_C2H2_sf.
DR   InterPro; IPR013087; Znf_C2H2_type.
DR   SMART; SM00355; ZnF_C2H2; 3.
DR   SUPFAM; SSF57667; SSF57667; 1.
DR   PROSITE; PS00028; ZINC_FINGER_C2H2_1; 3.
DR   PROSITE; PS50157; ZINC_FINGER_C2H2_2; 2.
PE   3: Inferred from homology;
KW   DNA-binding; Metal-binding; Nucleus; Reference proteome; Repeat;
KW   Transcription; Transcription regulation; Zinc; Zinc-finger.
FT   CHAIN           1..373
FT                   /note="AT-rich binding protein"
FT                   /id="PRO_0000378615"
FT   ZN_FING         29..52
FT                   /note="C2H2-type 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         306..330
FT                   /note="C2H2-type 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         336..359
FT                   /note="C2H2-type 3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   REGION          110..144
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        121..143
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   373 AA;  40437 MW;  0EC2DDD65DF379B0 CRC64;
     MGFPRILSKN NKIYTKLGEF CLSGDSFWIV CHTCQEELQT QDQFWKHIQD EHNFLHGVAK
     EHSRTSSYCL TDVEAAAATS GATTSQGAGS VTSVTVPLAL YHCSTKYSED DQREMDIHEA
     QQQQHQQQHQ QQQQLQQQQQ RDVAKELAEL HANAVAVASA AAAAANESST RSSSGIDIKI
     EPPCLTLPPE MQAAAAASNA TIYHLPQLGP AAVPPPPPTT GFVSANVSTS TTVSTTPPNV
     TGSHSVMQQQ AGVLTGSGLS TLSMSVGPST AMAAALLSTQ ELPKDSNSTT ASAGSAVSSD
     DGERWYICDY ETCGLKFKYK SRMELHRVVH SKERRFNCEL CSASFKQSCN LSTHRKKKHA
     LRGIKSEILP QRF