ID   ATBP_DROVI              Reviewed;         376 AA.
AC   B4M7J1;
DT   07-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   23-SEP-2008, sequence version 1.
DT   03-AUG-2022, entry version 67.
DE   RecName: Full=AT-rich binding protein {ECO:0000250|UniProtKB:Q86P48};
GN   Name=ATbp {ECO:0000250|UniProtKB:Q86P48}; ORFNames=GJ16440;
OS   Drosophila virilis (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila.
OX   NCBI_TaxID=7244;
RN   [1] {ECO:0000312|EMBL:EDW62758.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tucson 15010-1051.87 {ECO:0000312|EMBL:EDW62758.1};
RX   PubMed=17994087; DOI=10.1038/nature06341;
RG   Drosophila 12 genomes consortium;
RT   "Evolution of genes and genomes on the Drosophila phylogeny.";
RL   Nature 450:203-218(2007).
CC   -!- FUNCTION: May be a transcription factor for genes having (A+T)
CC       stretches in their promoter and/or enhancer regions. Binds to AT rich
CC       DNA (By similarity). {ECO:0000250|UniProtKB:Q86P48}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q86P48}.
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DR   EMBL; CH940653; EDW62758.1; -; Genomic_DNA.
DR   RefSeq; XP_002057272.2; XM_002057236.2.
DR   AlphaFoldDB; B4M7J1; -.
DR   STRING; 7244.FBpp0230857; -.
DR   EnsemblMetazoa; FBtr0442801; FBpp0399249; FBgn0203624.
DR   eggNOG; KOG1721; Eukaryota.
DR   HOGENOM; CLU_712250_0_0_1; -.
DR   InParanoid; B4M7J1; -.
DR   OMA; ERWYICD; -.
DR   OrthoDB; 1318335at2759; -.
DR   PhylomeDB; B4M7J1; -.
DR   Proteomes; UP000008792; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; ISS:UniProtKB.
DR   InterPro; IPR036236; Znf_C2H2_sf.
DR   InterPro; IPR013087; Znf_C2H2_type.
DR   SMART; SM00355; ZnF_C2H2; 3.
DR   SUPFAM; SSF57667; SSF57667; 1.
DR   PROSITE; PS00028; ZINC_FINGER_C2H2_1; 3.
DR   PROSITE; PS50157; ZINC_FINGER_C2H2_2; 2.
PE   3: Inferred from homology;
KW   DNA-binding; Metal-binding; Nucleus; Reference proteome; Repeat;
KW   Transcription; Transcription regulation; Zinc; Zinc-finger.
FT   CHAIN           1..376
FT                   /note="AT-rich binding protein"
FT                   /id="PRO_0000378617"
FT   ZN_FING         29..52
FT                   /note="C2H2-type 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         309..333
FT                   /note="C2H2-type 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         339..362
FT                   /note="C2H2-type 3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   REGION          143..165
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          213..250
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        213..227
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   376 AA;  40123 MW;  D128B3FA6B77A1BD CRC64;
     MGFPRILSKN NKIYTKLGEF CLSGDSFWIV CHTCQEELQT QDAFWKHIQD EHNFLHGLAK
     QEHGRNSSYC LPDVDAATAP ANQTALPVPL ALYHCAKYSE EEQREVAAAV ELHEAQQQQQ
     QQQQQQQQQQ QLQQQQQQRD SAELQAVTAA AESSARSNNS GSGIDIKVEP TSLTLTSEIQ
     VAAAAAAAAA AAGAAAAGAV TANTTIYHLS QVVPGPPPPP PPTPCFVTTP TAGGVSTTPP
     HPALAGPVGA GGNGGNGANA TVMQQACGTL GMPLLGVAAG QAELVAKESN STTASASSAV
     SSDDGERWYI CDYGACGLKF KYKSRMELHR VVHSKERRFN CDMCSASFKQ SCNLSTHRKK
     KHSLRGIKSE LLPQRF