PP448_ARATH
ID PP448_ARATH Reviewed; 532 AA.
AC Q9FJY9;
DT 10-FEB-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 03-AUG-2022, entry version 106.
DE RecName: Full=Pentatricopeptide repeat-containing protein At5g66500, mitochondrial;
DE Flags: Precursor;
GN Name=PCMP-E38; OrderedLocusNames=At5g66500; ORFNames=K1F13.16;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=9734815; DOI=10.1093/dnares/5.3.203;
RA Kotani H., Nakamura Y., Sato S., Asamizu E., Kaneko T., Miyajima N.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. VI. Sequence
RT features of the regions of 1,367,185 bp covered by 19 physically assigned
RT P1 and TAC clones.";
RL DNA Res. 5:203-216(1998).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14993207; DOI=10.1101/gr.1515604;
RA Castelli V., Aury J.-M., Jaillon O., Wincker P., Clepet C., Menard M.,
RA Cruaud C., Quetier F., Scarpelli C., Schaechter V., Temple G., Caboche M.,
RA Weissenbach J., Salanoubat M.;
RT "Whole genome sequence comparisons and 'full-length' cDNA sequences: a
RT combined approach to evaluate and improve Arabidopsis genome annotation.";
RL Genome Res. 14:406-413(2004).
RN [4]
RP GENE FAMILY.
RX PubMed=10809006; DOI=10.1023/a:1006352315928;
RA Aubourg S., Boudet N., Kreis M., Lecharny A.;
RT "In Arabidopsis thaliana, 1% of the genome codes for a novel protein family
RT unique to plants.";
RL Plant Mol. Biol. 42:603-613(2000).
RN [5]
RP GENE FAMILY.
RX PubMed=15269332; DOI=10.1105/tpc.104.022236;
RA Lurin C., Andres C., Aubourg S., Bellaoui M., Bitton F., Bruyere C.,
RA Caboche M., Debast C., Gualberto J., Hoffmann B., Lecharny A., Le Ret M.,
RA Martin-Magniette M.-L., Mireau H., Peeters N., Renou J.-P., Szurek B.,
RA Taconnat L., Small I.;
RT "Genome-wide analysis of Arabidopsis pentatricopeptide repeat proteins
RT reveals their essential role in organelle biogenesis.";
RL Plant Cell 16:2089-2103(2004).
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the PPR family. PCMP-E subfamily. {ECO:0000305}.
CC -!- WEB RESOURCE: Name=Pentatricopeptide repeat proteins;
CC URL="https://ppr.plantenergy.uwa.edu.au";
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DR EMBL; AB013389; BAB10926.1; -; Genomic_DNA.
DR EMBL; CP002688; AED98221.1; -; Genomic_DNA.
DR EMBL; BX832684; -; NOT_ANNOTATED_CDS; mRNA.
DR RefSeq; NP_201451.1; NM_126048.3.
DR AlphaFoldDB; Q9FJY9; -.
DR SMR; Q9FJY9; -.
DR STRING; 3702.AT5G66500.1; -.
DR PaxDb; Q9FJY9; -.
DR PRIDE; Q9FJY9; -.
DR ProteomicsDB; 249329; -.
DR EnsemblPlants; AT5G66500.1; AT5G66500.1; AT5G66500.
DR GeneID; 836782; -.
DR Gramene; AT5G66500.1; AT5G66500.1; AT5G66500.
DR KEGG; ath:AT5G66500; -.
DR Araport; AT5G66500; -.
DR TAIR; locus:2154965; AT5G66500.
DR eggNOG; KOG4197; Eukaryota.
DR HOGENOM; CLU_002706_0_1_1; -.
DR InParanoid; Q9FJY9; -.
DR OMA; LYMSCGL; -.
DR OrthoDB; 1344243at2759; -.
DR PhylomeDB; Q9FJY9; -.
DR PRO; PR:Q9FJY9; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9FJY9; baseline and differential.
DR Genevisible; Q9FJY9; AT.
DR GO; GO:0043231; C:intracellular membrane-bounded organelle; IBA:GO_Central.
DR GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR GO; GO:0009451; P:RNA modification; IBA:GO_Central.
DR Gene3D; 1.25.40.10; -; 3.
DR InterPro; IPR002885; Pentatricopeptide_repeat.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR Pfam; PF01535; PPR; 4.
DR Pfam; PF13041; PPR_2; 2.
DR TIGRFAMs; TIGR00756; PPR; 4.
DR PROSITE; PS51375; PPR; 11.
PE 2: Evidence at transcript level;
KW Mitochondrion; Reference proteome; Repeat; Transit peptide.
FT TRANSIT 1..33
FT /note="Mitochondrion"
FT /evidence="ECO:0000255"
FT CHAIN 34..532
FT /note="Pentatricopeptide repeat-containing protein
FT At5g66500, mitochondrial"
FT /id="PRO_0000363585"
FT REPEAT 48..82
FT /note="PPR 1"
FT REPEAT 83..117
FT /note="PPR 2"
FT REPEAT 118..148
FT /note="PPR 3"
FT REPEAT 149..183
FT /note="PPR 4"
FT REPEAT 184..218
FT /note="PPR 5"
FT REPEAT 223..248
FT /note="PPR 6"
FT REPEAT 250..280
FT /note="PPR 7"
FT REPEAT 281..314
FT /note="PPR 8"
FT REPEAT 315..345
FT /note="PPR 9"
FT REPEAT 346..380
FT /note="PPR 10"
FT REPEAT 383..413
FT /note="PPR 11"
FT REPEAT 419..453
FT /note="PPR 12"
FT REGION 458..532
FT /note="Type E motif; degenerate"
FT CONFLICT 225
FT /note="M -> I (in Ref. 3; BX832684)"
FT /evidence="ECO:0000305"
FT CONFLICT 232
FT /note="V -> I (in Ref. 3; BX832684)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 532 AA; 58910 MW; 05294AA42B94A26B CRC64;
MFACLRIGRF IRLGNVTVKS TNLVLRCVFI RNFATHADHL FDELPQRDLS SLNSQLSSHL
RSGNPNDTLA LFLQIHRASP DLSSHTFTPV LGACSLLSYP ETGRQVHALM IKQGAETGTI
SKTALIDMYS KYGHLVDSVR VFESVEEKDL VSWNALLSGF LRNGKGKEAL GVFAAMYRER
VEISEFTLSS VVKTCASLKI LQQGKQVHAM VVVTGRDLVV LGTAMISFYS SVGLINEAMK
VYNSLNVHTD EVMLNSLISG CIRNRNYKEA FLLMSRQRPN VRVLSSSLAG CSDNSDLWIG
KQIHCVALRN GFVSDSKLCN GLMDMYGKCG QIVQARTIFR AIPSKSVVSW TSMIDAYAVN
GDGVKALEIF REMCEEGSGV LPNSVTFLVV ISACAHAGLV KEGKECFGMM KEKYRLVPGT
EHYVCFIDIL SKAGETEEIW RLVERMMEND NQSIPCAIWV AVLSACSLNM DLTRGEYVAR
RLMEETGPEN ASIYVLVSNF YAAMGKWDVV EELRGKLKNK GLVKTAGHSL FI
