ID   PP4R2_XENTR             Reviewed;         401 AA.
AC   Q28IG6; Q5U4Y9;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   04-APR-2006, sequence version 1.
DT   03-AUG-2022, entry version 73.
DE   RecName: Full=Serine/threonine-protein phosphatase 4 regulatory subunit 2;
GN   Name=ppp4r2; ORFNames=TNeu083g13.1;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Neurula;
RG   Sanger Xenopus tropicalis EST/cDNA project;
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Regulatory subunit of serine/threonine-protein phosphatase 4
CC       (PP4). {ECO:0000250}.
CC   -!- SUBUNIT: Serine/threonine-protein phosphatase 4 (PP4) occurs in
CC       different assemblies of the catalytic and one or more regulatory
CC       subunits. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the PPP4R2 family. {ECO:0000305}.
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DR   EMBL; CR760404; CAJ82779.1; -; mRNA.
DR   EMBL; BC084901; AAH84901.1; -; mRNA.
DR   RefSeq; NP_001011151.1; NM_001011151.1.
DR   AlphaFoldDB; Q28IG6; -.
DR   STRING; 8364.ENSXETP00000062639; -.
DR   PaxDb; Q28IG6; -.
DR   DNASU; 496569; -.
DR   Ensembl; ENSXETT00000034749; ENSXETP00000034749; ENSXETG00000015932.
DR   GeneID; 496569; -.
DR   KEGG; xtr:496569; -.
DR   CTD; 151987; -.
DR   Xenbase; XB-GENE-6258889; ppp4r2.
DR   eggNOG; KOG3175; Eukaryota.
DR   HOGENOM; CLU_043908_1_1_1; -.
DR   InParanoid; Q28IG6; -.
DR   OrthoDB; 774806at2759; -.
DR   Proteomes; UP000008143; Chromosome 4.
DR   Proteomes; UP000790000; Unplaced.
DR   Bgee; ENSXETG00000015932; Expressed in 2-cell stage embryo and 13 other tissues.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0030289; C:protein phosphatase 4 complex; IBA:GO_Central.
DR   GO; GO:0019888; F:protein phosphatase regulator activity; IBA:GO_Central.
DR   GO; GO:0006470; P:protein dephosphorylation; IBA:GO_Central.
DR   InterPro; IPR015267; PPP4R2.
DR   PANTHER; PTHR16487; PTHR16487; 1.
DR   Pfam; PF09184; PPP4R2; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome.
FT   CHAIN           1..401
FT                   /note="Serine/threonine-protein phosphatase 4 regulatory
FT                   subunit 2"
FT                   /id="PRO_0000299374"
FT   REGION          139..401
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        139..200
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        201..215
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        223..254
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        283..306
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        307..334
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        335..364
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        373..387
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CONFLICT        308
FT                   /note="A -> T (in Ref. 2; AAH84901)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        355
FT                   /note="Missing (in Ref. 2; AAH84901)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   401 AA;  44226 MW;  770A2395966BE315 CRC64;
     MDVDRLQEAL KDFEKRGKKE ASSELDQFLC HVAKTGETVV QWPQFKEYFV FKLEKVMDDF
     RSSAPDQRGS PNPNVEYIPF DEMKQRILKI VTGFNGTPFT IQRLCELLTD PRRNYTGTDK
     FLRGVEKNVM VVSCVYPSSE KNSSTSLNRM NGVMFPSNSQ SYTDRSNVNG PGTPRPVNRP
     KFSLSSPMTT NGLPDSMENN ESDLQQKEKS QSDSVASEDE SQATTPKNKH SAEDSAETEE
     HEVKRLKFDT EEEEAACANP DASSEVSTEM AEEAESASAS ADKDKESCQS AQAADEESLM
     TPSESTEADS GERDSETVSV TEESSEESHQ MEESEQSETA CSLNSEEQNS AAAAASTVGT
     DTSEEEHLGT FGVKSTETLT LSPMENSEEA TDAPEEPMDQ D