ID   PP71_HCMVT              Reviewed;          28 AA.
AC   P24429;
DT   01-MAR-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-1992, sequence version 1.
DT   29-SEP-2021, entry version 51.
DE   RecName: Full=71 kDa phosphoprotein;
DE            Short=pp71;
DE   AltName: Full=71 kDa upper matrix phosphoprotein;
DE   AltName: Full=Phosphoprotein UL82;
DE            Short=ppUL82;
DE   AltName: Full=Tegument protein UL82;
DE   Flags: Fragment;
GN   Name=UL82;
OS   Human cytomegalovirus (strain Towne) (HHV-5) (Human herpesvirus 5).
OC   Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC   Herpesvirales; Herpesviridae; Betaherpesvirinae; Cytomegalovirus.
OX   NCBI_TaxID=10363;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=1850902; DOI=10.1016/0042-6822(91)90665-x;
RA   Pande H., Campo K., Tanamachi B., Zaia J.A.;
RT   "Human cytomegalovirus strain Towne pp65 gene: nucleotide sequence and
RT   expression in Escherichia coli.";
RL   Virology 182:220-228(1991).
CC   -!- FUNCTION: Stimulates viral immediate-early (IE) transcription.
CC       Counteracts the DAXX-mediated repression of viral transcription.
CC       Displaces a DAXX-binding protein, ATRX, from nuclear domain 10 sites
CC       (ND10) shortly after infection (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with the host protein DAXX; this interaction takes
CC       place at ND10 and induces the reversal of DAXX-mediated repression of
CC       viral transcription. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Virion tegument {ECO:0000305}. Host nucleus
CC       {ECO:0000250}. Note=Present in the nucleus shortly after infection as
CC       well as during the late phase of viral morphogenesis. Detected at
CC       nuclear domain 10 (ND10). Also found in dense bodies (By similarity).
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the herpesviridae pp71 family. {ECO:0000305}.
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DR   EMBL; M67443; AAA45995.1; -; Genomic_DNA.
DR   GO; GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0019033; C:viral tegument; IEA:UniProtKB-SubCell.
PE   3: Inferred from homology;
KW   Activator; Host nucleus; Host-virus interaction; Phosphoprotein; Virion;
KW   Virion tegument.
FT   CHAIN           1..>28
FT                   /note="71 kDa phosphoprotein"
FT                   /id="PRO_0000116291"
FT   REGION          1..28
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         28
SQ   SEQUENCE   28 AA;  2554 MW;  3C96A69C384425BD CRC64;
     MSQASSSPGE GPSSEAAAIS EAEAASGS