ID   PP85_HHV6Z              Reviewed;         610 AA.
AC   Q9QJ49;
DT   03-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   02-JUN-2021, entry version 41.
DE   RecName: Full=Phosphoprotein 85;
DE            Short=pp85;
DE   AltName: Full=Protein U14;
GN   Name=U14;
OS   Human herpesvirus 6B (strain Z29) (HHV-6 variant B) (Human B lymphotropic
OS   virus).
OC   Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC   Herpesvirales; Herpesviridae; Betaherpesvirinae; Roseolovirus.
OX   NCBI_TaxID=36351;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=10482553; DOI=10.1128/jvi.73.10.8040-8052.1999;
RA   Dominguez G., Dambaugh T.R., Stamey F.R., Dewhurst S., Inoue N.,
RA   Pellett P.E.;
RT   "Human herpesvirus 6B genome sequence: coding content and comparison with
RT   human herpesvirus 6A.";
RL   J. Virol. 73:8040-8052(1999).
CC   -!- SUBCELLULAR LOCATION: Virion tegument {ECO:0000250}. Host cytoplasm.
CC       Note=Expressed exclusively at the cytoplasmic level during the late
CC       phase of the virus replication cycle. Also found in dense bodies (By
CC       similarity). {ECO:0000250}.
CC   -!- PTM: Phosphorylated. {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the herpesviridae pp85 family. {ECO:0000305}.
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DR   EMBL; AF157706; AAD49629.1; -; Genomic_DNA.
DR   RefSeq; NP_050195.1; NC_000898.1.
DR   SMR; Q9QJ49; -.
DR   BioGRID; 1678239; 2.
DR   PRIDE; Q9QJ49; -.
DR   GeneID; 1497013; -.
DR   KEGG; vg:1497013; -.
DR   Proteomes; UP000006930; Genome.
DR   GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0019033; C:viral tegument; IEA:UniProtKB-SubCell.
DR   InterPro; IPR006731; Herpes_pp85.
DR   Pfam; PF04637; Herpes_pp85; 1.
PE   3: Inferred from homology;
KW   Host cytoplasm; Phosphoprotein; Reference proteome; Virion;
KW   Virion tegument.
FT   CHAIN           1..610
FT                   /note="Phosphoprotein 85"
FT                   /id="PRO_0000408410"
FT   REGION          462..530
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          543..610
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        465..517
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        551..591
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        596..610
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   610 AA;  69823 MW;  0D1FACAEA8E7BAEA CRC64;
     MITHAMEGSK TFNIPTFVLD ENCNFIPDVL SRANAKFIKE VLIRDSYNAV CLANSFIPMA
     TQTVEQILII ITKFKFSRSR DLLMSVFRLG VHINRFYAGK NQVKHMITMM KSLFDTEEAM
     RQLDRALMGL FVDARDNSYM PLIALSLHEN GLPDSKFIKA VRLIQTTVNS FHNRPDADIE
     QYAEKLRAYN YLYKIPKYSL KEAVDIYSDN LKDLTIGVNK KPTLLFTSSD DAYLSHIYND
     LLFLTSTWNM IYNCKKEIRR LNTWIKYEIN SIMETAVLVG FQLPDLKETI LDLAALISNM
     NLVSPDKELF PHYKLILAKL FEICIFATKA NICILPSFIK GHLIEFEDVL KRSNDDEDLN
     YLLLKSRDSD DEYDEDKPPI QVDPGRVDNV LTDSDFFNVT PENAFSSIAI MPISYDKTID
     VEDNEIQVLE VEMQSLSAVV YGAVASKYGL SLEQVIRKLN RNEGRTSSRA SPSHSTSTVP
     YSPPQSDRST PTSILRQRVP MRSNSRSSSV SFSQEDSNRS HYSDETNISD YSYPMADLEL
     EDEEPMEDHP HSPQSTSSNN SMSRQSRALQ NGQRRRAPTM VPSSQTRRQN NARPRRVARR
     LTEMMNDARL