PPAN_ARATH
ID PPAN_ARATH Reviewed; 345 AA.
AC Q9ASU7; Q9FLT1;
DT 19-OCT-2002, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 108.
DE RecName: Full=Peter Pan-like protein;
GN Name=PPAN; OrderedLocusNames=At5g61770; ORFNames=MAC9.8, MAC9_70;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=9628582; DOI=10.1093/dnares/5.1.41;
RA Sato S., Kaneko T., Kotani H., Nakamura Y., Asamizu E., Miyajima N.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. IV. Sequence
RT features of the regions of 1,456,315 bp covered by nineteen physically
RT assigned P1 and TAC clones.";
RL DNA Res. 5:41-54(1998).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP CHARACTERIZATION.
RX PubMed=10359593; DOI=10.1091/mbc.10.6.1733;
RA Migeon J.C., Garfinkel M.S., Edgar B.A.;
RT "Cloning and characterization of peter pan, a novel Drosophila gene
RT required for larval growth.";
RL Mol. Biol. Cell 10:1733-1744(1999).
CC -!- FUNCTION: May play a role in cell growth, differentiation and cell
CC cycle progression.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=1;
CC Comment=A number of isoforms are produced. According to EST
CC sequences.;
CC Name=1;
CC IsoId=Q9ASU7-1; Sequence=Displayed;
CC -!- SIMILARITY: Belongs to the PPAN family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAB10077.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AB010069; BAB10077.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002688; AED97514.1; -; Genomic_DNA.
DR EMBL; AF361824; AAK32836.1; -; mRNA.
DR EMBL; AY056064; AAL06964.1; -; mRNA.
DR EMBL; AY069910; AAL47460.1; -; mRNA.
DR RefSeq; NP_568939.2; NM_125571.5.
DR RefSeq; NP_851242.1; NM_180911.2. [Q9ASU7-1]
DR RefSeq; NP_974976.1; NM_203247.1.
DR AlphaFoldDB; Q9ASU7; -.
DR SMR; Q9ASU7; -.
DR BioGRID; 21543; 1.
DR STRING; 3702.AT5G61770.2; -.
DR iPTMnet; Q9ASU7; -.
DR PaxDb; Q9ASU7; -.
DR PRIDE; Q9ASU7; -.
DR ProteomicsDB; 249036; -. [Q9ASU7-1]
DR EnsemblPlants; AT5G61770.1; AT5G61770.1; AT5G61770. [Q9ASU7-1]
DR GeneID; 836299; -.
DR Gramene; AT5G61770.1; AT5G61770.1; AT5G61770. [Q9ASU7-1]
DR KEGG; ath:AT5G61770; -.
DR Araport; AT5G61770; -.
DR eggNOG; KOG2963; Eukaryota.
DR HOGENOM; CLU_026936_1_0_1; -.
DR InParanoid; Q9ASU7; -.
DR OrthoDB; 1199197at2759; -.
DR PhylomeDB; Q9ASU7; -.
DR PRO; PR:Q9ASU7; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9ASU7; baseline and differential.
DR Genevisible; Q9ASU7; AT.
DR GO; GO:0030687; C:preribosome, large subunit precursor; IBA:GO_Central.
DR GO; GO:0019843; F:rRNA binding; IBA:GO_Central.
DR GO; GO:0000027; P:ribosomal large subunit assembly; IBA:GO_Central.
DR GO; GO:0006364; P:rRNA processing; IEA:InterPro.
DR InterPro; IPR007109; Brix.
DR InterPro; IPR045112; PPAN-like.
DR PANTHER; PTHR12661; PTHR12661; 1.
DR Pfam; PF04427; Brix; 1.
DR SMART; SM00879; Brix; 1.
DR PROSITE; PS50833; BRIX; 1.
PE 1: Evidence at protein level;
KW Alternative splicing; Coiled coil; Reference proteome.
FT CHAIN 1..345
FT /note="Peter Pan-like protein"
FT /id="PRO_0000120247"
FT DOMAIN 34..295
FT /note="Brix"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00034"
FT REGION 308..345
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 307..329
FT /evidence="ECO:0000255"
FT COMPBIAS 319..345
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 345 AA; 38841 MW; 8B7C8BEE162FFCE6 CRC64;
MGRFKNNKKS RVIGKPIAKK NQEDVSHVTG DKIPKSFVFS RMKLAGPVKQ LQMDLRKLML
PYTALSLKEK KRNTLRDFLN VSGPMGVTHF LMLSKTASSL SLRVARTPQG PTLTFKIHQY
SLASDIAQSQ LRPRCPQDLF KSPPLIVLSG FGSQELHLKL ATIMFQNIFP AIDINTVKLS
TCQRLVLLNY NKDTKLIDFR HYSIRLQPVG VSRRIRKFVQ NHQVPDLRNL QDVSDFVTKA
GYGSESEGDE EAATVTLSSD LGRVNKGATK SAVKLQEIGP RMTMQLVKVE EGLCTGGIIF
SEYDVDGKKE KLKKKQDEEE EEDSEEEGEE GSEEDGEDMD EDFED
