ID   PPAN_DICDI              Reviewed;         426 AA.
AC   Q54N44;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 79.
DE   RecName: Full=Peter Pan-like protein;
GN   Name=ppan; ORFNames=DDB_G0285515;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- SIMILARITY: Belongs to the PPAN family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AAFI02000079; EAL64595.1; -; Genomic_DNA.
DR   RefSeq; XP_638099.1; XM_633007.1.
DR   AlphaFoldDB; Q54N44; -.
DR   STRING; 44689.DDB0304596; -.
DR   PaxDb; Q54N44; -.
DR   EnsemblProtists; EAL64595; EAL64595; DDB_G0285515.
DR   GeneID; 8625147; -.
DR   KEGG; ddi:DDB_G0285515; -.
DR   dictyBase; DDB_G0285515; ppan.
DR   eggNOG; KOG2963; Eukaryota.
DR   HOGENOM; CLU_026936_0_0_1; -.
DR   InParanoid; Q54N44; -.
DR   OMA; MWHEYIH; -.
DR   PhylomeDB; Q54N44; -.
DR   PRO; PR:Q54N44; -.
DR   Proteomes; UP000002195; Chromosome 4.
DR   GO; GO:0030687; C:preribosome, large subunit precursor; IBA:GO_Central.
DR   GO; GO:0019843; F:rRNA binding; IBA:GO_Central.
DR   GO; GO:0000027; P:ribosomal large subunit assembly; IBA:GO_Central.
DR   GO; GO:0006364; P:rRNA processing; IEA:InterPro.
DR   InterPro; IPR007109; Brix.
DR   InterPro; IPR045112; PPAN-like.
DR   PANTHER; PTHR12661; PTHR12661; 1.
DR   Pfam; PF04427; Brix; 1.
DR   SMART; SM00879; Brix; 1.
DR   PROSITE; PS50833; BRIX; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Reference proteome.
FT   CHAIN           1..426
FT                   /note="Peter Pan-like protein"
FT                   /id="PRO_0000371346"
FT   DOMAIN          46..320
FT                   /note="Brix"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00034"
FT   REGION          1..34
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          339..426
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          329..373
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        1..18
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        339..408
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   426 AA;  48871 MW;  69B8FF527A41D835 CRC64;
     MAPPNKSSNR NKSNNNNNKN KVKSKKSKRS IDETPEALDL DQAAISKSIV YKRGDCNKGI
     KKLVKEFRQV MEPYTATKLQ ETSDNTTKDF VNIAAHYGVS HLVGFSSTDI GSYMAMARLP
     KGPTTTFKIQ EYSFQRDVAK AKIRPTSFEK SYLNSPLVVL NGFTRGTPHL EMVQNMVQSL
     FPSINVYTLK LSTCKRVVLF NYNKETDNVE FRHYAIKVSN VGVNRSIKRI IQSKIPDISN
     LGDISDYVMN GLGATESDYE DANDGQVELS SKMINSKAKN IKLERKGLDI NTTQKRAIKL
     EEIGPRMNLS LLKVEDDLYK GEVLYHQYIK KSDIEKEEAK LRRDEAKIEK ERRRKDQEAN
     VDKKIKEKER KRKYLDQGNE DKHSDDDDEE WYRKEVGENP DETFKNNRKS RSTGGGRPNK
     KFKSKK