ID   PPDD_HAEIN              Reviewed;         149 AA.
AC   P44623;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   03-AUG-2022, entry version 115.
DE   RecName: Full=Prepilin peptidase-dependent protein D homolog;
DE   Flags: Precursor;
GN   Name=ppdD; OrderedLocusNames=HI_0299;
OS   Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=71421;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX   PubMed=7542800; DOI=10.1126/science.7542800;
RA   Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA   Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA   McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA   Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA   Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA   Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA   Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA   Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT   "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT   Rd.";
RL   Science 269:496-512(1995).
CC   -!- SUBCELLULAR LOCATION: Fimbrium. Membrane {ECO:0000255}; Single-pass
CC       membrane protein {ECO:0000255}.
CC   -!- SIMILARITY: Belongs to the N-Me-Phe pilin family. {ECO:0000305}.
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DR   EMBL; L42023; AAC21963.1; -; Genomic_DNA.
DR   PIR; C64147; C64147.
DR   RefSeq; NP_438466.1; NC_000907.1.
DR   RefSeq; WP_005694367.1; NC_000907.1.
DR   AlphaFoldDB; P44623; -.
DR   SMR; P44623; -.
DR   STRING; 71421.HI_0299; -.
DR   EnsemblBacteria; AAC21963; AAC21963; HI_0299.
DR   KEGG; hin:HI_0299; -.
DR   PATRIC; fig|71421.8.peg.315; -.
DR   eggNOG; COG4969; Bacteria.
DR   HOGENOM; CLU_091705_4_1_6; -.
DR   OMA; RILTWDC; -.
DR   PhylomeDB; P44623; -.
DR   BioCyc; HINF71421:G1GJ1-317-MON; -.
DR   Proteomes; UP000000579; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0044096; C:type IV pilus; IBA:GO_Central.
DR   GO; GO:0043683; P:type IV pilus assembly; IBA:GO_Central.
DR   GO; GO:0043107; P:type IV pilus-dependent motility; IBA:GO_Central.
DR   InterPro; IPR012902; N_methyl_site.
DR   InterPro; IPR045584; Pilin-like.
DR   Pfam; PF07963; N_methyl; 1.
DR   SUPFAM; SSF54523; SSF54523; 1.
DR   TIGRFAMs; TIGR02532; IV_pilin_GFxxxE; 1.
DR   PROSITE; PS00409; PROKAR_NTER_METHYL; 1.
PE   3: Inferred from homology;
KW   Fimbrium; Membrane; Methylation; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   PROPEP          1..12
FT                   /note="Leader sequence"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01070"
FT                   /id="PRO_0000024282"
FT   CHAIN           13..149
FT                   /note="Prepilin peptidase-dependent protein D homolog"
FT                   /id="PRO_0000024283"
FT   TRANSMEM        10..30
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   MOD_RES         13
FT                   /note="N-methylphenylalanine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01070"
SQ   SEQUENCE   149 AA;  15509 MW;  5056C8C0BE74F662 CRC64;
     MKLTTLQTLK KGFTLIELMI VIAIIAILAT IAIPSYQNYT KKAAVSELLQ ASAPYKADVE
     LCVYSTNETT SCTGGKNGIA ADIKTAKGYV ASVITQSGGI TVKGNGTLAN MEYILQAKGN
     AAAGVTWTTT CKGTDASLFP ANFCGSVTK