ID   PPE11_MYCTO             Reviewed;         518 AA.
AC   P9WI38; L0T5E9; Q6MX41; Q7D9S7;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 30.
DE   RecName: Full=PPE family protein PPE11 {ECO:0000250|UniProtKB:P9WI39};
GN   Name=PPE11; OrderedLocusNames=MT0469;
OS   Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA   Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA   Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA   Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA   Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA   Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT   "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT   laboratory strains.";
RL   J. Bacteriol. 184:5479-5490(2002).
CC   -!- FUNCTION: May play an important role in the persistence of mycobacteria
CC       in host cells. {ECO:0000250|UniProtKB:P9WI39}.
CC   -!- SUBCELLULAR LOCATION: Secreted, cell wall
CC       {ECO:0000250|UniProtKB:P9WI39}. Note=Cell wall-associated.
CC       {ECO:0000250|UniProtKB:P9WI39}.
CC   -!- SIMILARITY: Belongs to the mycobacterial PPE family. {ECO:0000305}.
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DR   EMBL; AE000516; AAK44692.1; -; Genomic_DNA.
DR   PIR; F70831; F70831.
DR   RefSeq; WP_003898460.1; NZ_KK341227.1.
DR   AlphaFoldDB; P9WI38; -.
DR   SMR; P9WI38; -.
DR   EnsemblBacteria; AAK44692; AAK44692; MT0469.
DR   KEGG; mtc:MT0469; -.
DR   PATRIC; fig|83331.31.peg.497; -.
DR   HOGENOM; CLU_000243_5_2_11; -.
DR   Proteomes; UP000001020; Chromosome.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.1260.20; -; 1.
DR   InterPro; IPR043641; PPE-PPW_C.
DR   InterPro; IPR000030; PPE_family.
DR   InterPro; IPR038332; PPE_sf.
DR   Pfam; PF00823; PPE; 1.
DR   Pfam; PF18878; PPE-PPW; 1.
PE   3: Inferred from homology;
KW   Cell wall; Secreted; Virulence.
FT   CHAIN           1..518
FT                   /note="PPE family protein PPE11"
FT                   /id="PRO_0000428074"
FT   REGION          177..197
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          346..375
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        178..196
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   518 AA;  52784 MW;  7AFA41201D3DF572 CRC64;
     MTSALIWMAS PPEVHSALLS SGPGPGPVLA AATGWSSLGR EYAAVAEELG ALLAAVQAGV
     WQGPSAESFA AACLPYLSWL TQASADCAAA AARLEAVTAA YAAALVAMPT LAELAANHAT
     HGAMVATNFF GINTIPIAVN EADYVRMWLQ AATTMATYQA VADSAVRSIP DSVPPPRILK
     SNAQSQHSSS NNSGGADPVD DFIAEILKII TGGRVIWDPE AGTVNGLPYD AYTNPGTLMW
     WIARSLELLQ DFQEFAKLLF TNPVKAFQFL VDLILFDWPT HMLQLATWLA ENPQLLVAAL
     TPAISGLGAV SGLAGLTGLV PQPPVVPAPA PDAVVPTVLP LAGTATPTTA PASAPAAGAA
     PGPPAGTATA TSASVPTSAG GFPPYLVGSG PGIDFDAGTP AGSRRAQPAA DNVTAVAAAQ
     VSARHQARRC RRAAAKERGN ADEFVDMDSG PAIPPSGERD AWASNSGVGG LGFAGTASNE
     TVAAPAGLTT LADDEFQCGP RMPMLPGAWD LGTWDRGD