ID   PPE13_MYCTO             Reviewed;         443 AA.
AC   P9WI34; L0T563; Q10540;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 30.
DE   RecName: Full=Uncharacterized PPE family protein PPE13;
GN   Name=PPE13; OrderedLocusNames=MT0901;
OS   Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA   Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA   Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA   Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA   Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA   Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT   "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT   laboratory strains.";
RL   J. Bacteriol. 184:5479-5490(2002).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the mycobacterial PPE family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAK45143.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AE000516; AAK45143.1; ALT_INIT; Genomic_DNA.
DR   PIR; C70780; C70780.
DR   RefSeq; WP_003900226.1; NZ_KK341227.1.
DR   AlphaFoldDB; P9WI34; -.
DR   SMR; P9WI34; -.
DR   EnsemblBacteria; AAK45143; AAK45143; MT0901.
DR   KEGG; mtc:MT0901; -.
DR   PATRIC; fig|83331.31.peg.967; -.
DR   HOGENOM; CLU_000243_1_2_11; -.
DR   Proteomes; UP000001020; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   Gene3D; 1.20.1260.20; -; 1.
DR   InterPro; IPR002989; Mycobac_pentapep.
DR   InterPro; IPR000030; PPE_family.
DR   InterPro; IPR038332; PPE_sf.
DR   Pfam; PF01469; Pentapeptide_2; 3.
DR   Pfam; PF00823; PPE; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Repeat; Transmembrane; Transmembrane helix.
FT   CHAIN           1..443
FT                   /note="Uncharacterized PPE family protein PPE13"
FT                   /id="PRO_0000428076"
FT   TRANSMEM        15..35
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        38..58
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        59..79
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        181..201
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          231..270
FT                   /note="4 X 10 AA approximate repeats"
SQ   SEQUENCE   443 AA;  43592 MW;  C58BEC607F0675E2 CRC64;
     MNFMVLPPEV NSARIYAGAG PAPMLAAAVA WDGLAAELGM AAASFSLLIS GLTAGPGSAW
     QGPAAAAMAA AAAPYLSWLN AATARAEGAA AGAKAAAAVY EAARAATAHP ALVAANRNQL
     LSLVLSNLFG QNLPAIAATE ASYEQLWAQD VAAMVGYHGG ASTVASQLTP WQQLLSVLPP
     VVTAAPAGAV GVPAALAIPA LGVENIGVGN FLGIGNIGNN NVGSGNTGDY NFGIGNIGNA
     NLGNGNIGNA NLGSGNAGFF NFGNGNDGNT NFGSGNAGFL NIGSGNEGSG NLGFGNAGDD
     NTGWGNSGDT NTGGFNSGDL NTGIGSPVTQ GVANSGFGNT GTGHSGFFNS GNSGSGFQNL
     GNGSSGFGNA SDTSSGFQNA GTALTRASST WADSPRAWPI RAPSRLQVWR TRATTARECS
     IRVIISRVSS TGAPPQKKVG NSG