ID   PPE16_MYCTU             Reviewed;         618 AA.
AC   P9WI29; L0T7E9; Q79FS0; Q8VK65;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   03-AUG-2022, entry version 32.
DE   RecName: Full=Uncharacterized PPE family protein PPE16;
DE   Flags: Precursor;
GN   Name=PPE16; OrderedLocusNames=Rv1135c;
OS   Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83332;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=9634230; DOI=10.1038/31159;
RA   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA   Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA   Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA   Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA   Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA   Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA   Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA   Barrell B.G.;
RT   "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT   genome sequence.";
RL   Nature 393:537-544(1998).
CC   -!- SIMILARITY: Belongs to the mycobacterial PPE family. {ECO:0000305}.
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DR   EMBL; AL123456; CCP43889.1; -; Genomic_DNA.
DR   PIR; H70552; H70552.
DR   RefSeq; WP_003405919.1; NZ_NVQJ01000021.1.
DR   RefSeq; YP_177790.1; NC_000962.3.
DR   AlphaFoldDB; P9WI29; -.
DR   SMR; P9WI29; -.
DR   STRING; 83332.Rv1135c; -.
DR   PaxDb; P9WI29; -.
DR   DNASU; 885131; -.
DR   GeneID; 885131; -.
DR   KEGG; mtu:Rv1135c; -.
DR   TubercuList; Rv1135c; -.
DR   eggNOG; COG5263; Bacteria.
DR   eggNOG; COG5651; Bacteria.
DR   OMA; NVMHTDS; -.
DR   PhylomeDB; P9WI29; -.
DR   Proteomes; UP000001584; Chromosome.
DR   GO; GO:0052572; P:response to host immune response; IBA:GO_Central.
DR   Gene3D; 1.20.1260.20; -; 1.
DR   InterPro; IPR002989; Mycobac_pentapep.
DR   InterPro; IPR000030; PPE_family.
DR   InterPro; IPR038332; PPE_sf.
DR   Pfam; PF01469; Pentapeptide_2; 9.
DR   Pfam; PF00823; PPE; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Signal.
FT   SIGNAL          1..29
FT                   /evidence="ECO:0000255"
FT   CHAIN           30..618
FT                   /note="Uncharacterized PPE family protein PPE16"
FT                   /id="PRO_0000379587"
FT   REGION          598..618
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   618 AA;  60207 MW;  021E3275747595A3 CRC64;
     MSFLVLPPEV NSALMFAGAG SGPTLAAAAA WDGLAAELGQ AANSFSSATA ALADTAWQGP
     AATAMAAAAA PYASWLSTAA TRALSAAAQA KAAAAVYEAA RAATVDPLLV AANRHQLVSL
     VLSNLFGQNA PAIAATEAAY EQLWAADVAA MVSYHSGASA VAAQLAPWAQ AVRALPNPTA
     PALASGPAAL AIPALGIGNT GIGNIFSIGN IGDYNLGNGN TGNANLGSGN TGQANLGSGN
     TGFFNFGSGN TANTNFGSGN LGNLNLGSGN DGNGNFGLGN IGDGNRGSGN VGSFNFGTAN
     AGSFNVGSAN HGSPNVGFAN LGNNNLGIAN LGNNNLGIAN LGNNNIGIGL TGDNMIGIGA
     LNSGIGNLGF GNSGNNNIGL FNSGNNNIGF FNSGDSNFGF FNSGDTNTGF GNAGFTNTGF
     GNAGSGNFGF GNAGNNNFGF GNSGFENMGV GNSGAYNTGS FNSGTLNTGD LNSGDFNTGW
     ANSGDINTGG FHSGDLNTGF GSPVDQPVMN SGFGNIGTGN SGFNNSGDAN SGFQNTNTGA
     FFIGHSGLLN SGGGQHVGIS NSGTGFNTGL FNTGFNNTGI GNSATNAAFT TTSGVANSGD
     NSSGGFNAGN DQSGFFDG