ID   PPE28_MYCTU             Reviewed;         655 AA.
AC   P9WI11; L0T9A6; Q79FK2; Q7D7Y0;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   03-AUG-2022, entry version 33.
DE   RecName: Full=Uncharacterized PPE family protein PPE28;
GN   Name=PPE28; OrderedLocusNames=Rv1800;
OS   Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83332;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=9634230; DOI=10.1038/31159;
RA   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA   Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA   Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA   Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA   Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA   Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA   Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA   Barrell B.G.;
RT   "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT   genome sequence.";
RL   Nature 393:537-544(1998).
CC   -!- SIMILARITY: Belongs to the mycobacterial PPE family. {ECO:0000305}.
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DR   EMBL; AL123456; CCP44566.1; -; Genomic_DNA.
DR   PIR; A70931; A70931.
DR   RefSeq; WP_003901256.1; NZ_NVQJ01000037.1.
DR   RefSeq; YP_177839.1; NC_000962.3.
DR   AlphaFoldDB; P9WI11; -.
DR   SMR; P9WI11; -.
DR   STRING; 83332.Rv1800; -.
DR   ESTHER; myctu-Rv1800; PE-PPE.
DR   PaxDb; P9WI11; -.
DR   DNASU; 885465; -.
DR   GeneID; 885465; -.
DR   KEGG; mtu:Rv1800; -.
DR   TubercuList; Rv1800; -.
DR   eggNOG; COG5651; Bacteria.
DR   OMA; LAGIYYV; -.
DR   PhylomeDB; P9WI11; -.
DR   Proteomes; UP000001584; Chromosome.
DR   GO; GO:0052572; P:response to host immune response; IBA:GO_Central.
DR   Gene3D; 1.20.1260.20; -; 1.
DR   Gene3D; 3.40.50.1820; -; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR013228; PE-PPE_C.
DR   InterPro; IPR000030; PPE_family.
DR   InterPro; IPR038332; PPE_sf.
DR   Pfam; PF08237; PE-PPE; 1.
DR   Pfam; PF00823; PPE; 1.
DR   SUPFAM; SSF53474; SSF53474; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..655
FT                   /note="Uncharacterized PPE family protein PPE28"
FT                   /id="PRO_0000379111"
FT   DOMAIN          245..469
FT                   /note="PE-PPE"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   655 AA;  67067 MW;  FE1DF5044C927A4F CRC64;
     MLPNFAVLPP EVNSARVFAG AGSAPMLAAA AAWDDLASEL HCAAMSFGSV TSGLVVGWWQ
     GSASAAMVDA AASYIGWLST SAAHAEGAAG LARAAVSVFE EALAATVHPA MVAANRAQVA
     SLVASNLFGQ NAPAIAALES LYECMWAQDA AAMAGYYVGA SAVATQLASW LQRLQSIPGA
     ASLDARLPSS AEAPMGVVRA VNSAIAANAA AAQTVGLVMG GSGTPIPSAR YVELANALYM
     SGSVPGVIAQ ALFTPQGLYP VVVIKNLTFD SSVAQGAVIL ESAIRQQIAA GNNVTVFGYS
     QSATISSLVM ANLAASADPP SPDELSFTLI GNPNNPNGGV ATRFPGISFP SLGVTATGAT
     PHNLYPTKIY TIEYDGVADF PRYPLNFVST LNAIAGTYYV HSNYFILTPE QIDAAVPLTN
     TVGPTMTQYY IIRTENLPLL EPLRSVPIVG NPLANLVQPN LKVIVNLGYG DPAYGYSTSP
     PNVATPFGLF PEVSPVVIAD ALVAGTQQGI GDFAYDVSHL ELPLPADGST MPSTAPGSGT
     PVPPLSIDSL IDDLQVANRN LANTISKVAA TSYATVLPTA DIANAALTIV PSYNIHLFLE
     GIQQALKGDP MGLVNAVGYP LAADVALFTA AGGLQLLIII SAGRTIANDI SAIVP