PPE32_MYCTU
ID PPE32_MYCTU Reviewed; 410 AA.
AC P9WI05; L0TAN8; Q79FJ6; Q7D7X4;
DT 16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT 25-MAY-2022, sequence version 2.
DT 03-AUG-2022, entry version 32.
DE RecName: Full=Uncharacterized PPE family protein PPE32;
GN Name=PPE32; OrderedLocusNames=Rv1808;
OS Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium tuberculosis complex.
OX NCBI_TaxID=83332;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25618 / H37Rv;
RX PubMed=9634230; DOI=10.1038/31159;
RA Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA Barrell B.G.;
RT "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT genome sequence.";
RL Nature 393:537-544(1998).
RN [2]
RP PROTEIN SEQUENCE OF 1-15, AND SEQUENCE REVISION TO N-TERMINUS.
RC STRAIN=H37Rv;
RX PubMed=34915127; DOI=10.1016/j.ygeno.2021.12.001;
RA Shi J., Meng S., Wan L., Zhang Z., Jiang S., Zhu H., Dai E., Chang L.,
RA Gao H., Wan K., Zhang L., Zhao X., Liu H., Lyu Z., Zhang Y., Xu P.;
RT "Deep N-terminomics of Mycobacterium tuberculosis H37Rv extensively correct
RT annotated encoding genes.";
RL Genomics 114:292-304(2022).
RN [3]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC STRAIN=ATCC 25618 / H37Rv;
RX PubMed=21969609; DOI=10.1074/mcp.m111.011627;
RA Kelkar D.S., Kumar D., Kumar P., Balakrishnan L., Muthusamy B., Yadav A.K.,
RA Shrivastava P., Marimuthu A., Anand S., Sundaram H., Kingsbury R.,
RA Harsha H.C., Nair B., Prasad T.S., Chauhan D.S., Katoch K., Katoch V.M.,
RA Kumar P., Chaerkady R., Ramachandran S., Dash D., Pandey A.;
RT "Proteogenomic analysis of Mycobacterium tuberculosis by high resolution
RT mass spectrometry.";
RL Mol. Cell. Proteomics 10:M111.011627-M111.011627(2011).
CC -!- SIMILARITY: Belongs to the mycobacterial PPE family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CCP44574.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000269|PubMed:34915127};
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DR EMBL; AL123456; CCP44574.1; ALT_INIT; Genomic_DNA.
DR PIR; A70932; A70932.
DR RefSeq; WP_003906680.1; NZ_NVQJ01000070.1.
DR RefSeq; YP_177844.1; NC_000962.3.
DR AlphaFoldDB; P9WI05; -.
DR SMR; P9WI05; -.
DR STRING; 83332.Rv1808; -.
DR PaxDb; P9WI05; -.
DR GeneID; 885590; -.
DR KEGG; mtu:Rv1808; -.
DR PATRIC; fig|83332.111.peg.2012; -.
DR TubercuList; Rv1808; -.
DR eggNOG; COG5651; Bacteria.
DR OMA; FGEMAMA; -.
DR Proteomes; UP000001584; Chromosome.
DR GO; GO:0052572; P:response to host immune response; IBA:GO_Central.
DR Gene3D; 1.20.1260.20; -; 1.
DR InterPro; IPR022171; PPE_C.
DR InterPro; IPR000030; PPE_family.
DR InterPro; IPR038332; PPE_sf.
DR Pfam; PF00823; PPE; 1.
DR Pfam; PF12484; PPE-SVP; 1.
PE 1: Evidence at protein level;
KW Direct protein sequencing; Reference proteome.
FT CHAIN 1..410
FT /note="Uncharacterized PPE family protein PPE32"
FT /id="PRO_0000379112"
SQ SEQUENCE 410 AA; 40030 MW; F0F0115E61B5DC0D CRC64;
MLDFGALPPE INSGRMYAGP GSGPLLAAAA AWDALAAELY SAAASYGSTI EGLTVAPWMG
PSSITMAAAV APYVAWISVT AGQAEQAGAQ AKIAAGVYET AFAATVPPPV IEANRALLMS
LVATNIFGQN TPAIAATEAH YAEMWAQDAA AMYGYAGSSA TASQLAPFSE PPQTTNPSAT
AAQSAVVAQA AGAAASSDIT AQLSQLISLL PSTLQSLATT ATATSASAGW DTVLQSITTI
LANLTGPYSI IGLGAIPGGW WLTFGQILGL AQNAPGVAAL LGPKAAAGAL SPLAPLRGGY
IGDITPLGGG ATGGIARAIY VGSLSVPQGW AEAAPVMRAV ASVLPGTGAA PALAAEAPGA
LFGEMALSSL AGRALAGTAV RSGAGAARVA GGSVTEDVAS TTTIIVIPAD