ID   PPE40_MYCTU             Reviewed;         615 AA.
AC   P9WHZ7; L0T9D9; Q79FF2; Q7D7A1;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   03-AUG-2022, entry version 34.
DE   RecName: Full=Uncharacterized PPE family protein PPE40;
GN   Name=PPE40; OrderedLocusNames=Rv2356c;
OS   Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83332;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=9634230; DOI=10.1038/31159;
RA   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA   Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA   Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA   Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA   Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA   Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA   Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA   Barrell B.G.;
RT   "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT   genome sequence.";
RL   Nature 393:537-544(1998).
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=21969609; DOI=10.1074/mcp.m111.011627;
RA   Kelkar D.S., Kumar D., Kumar P., Balakrishnan L., Muthusamy B., Yadav A.K.,
RA   Shrivastava P., Marimuthu A., Anand S., Sundaram H., Kingsbury R.,
RA   Harsha H.C., Nair B., Prasad T.S., Chauhan D.S., Katoch K., Katoch V.M.,
RA   Kumar P., Chaerkady R., Ramachandran S., Dash D., Pandey A.;
RT   "Proteogenomic analysis of Mycobacterium tuberculosis by high resolution
RT   mass spectrometry.";
RL   Mol. Cell. Proteomics 10:M111.011627-M111.011627(2011).
CC   -!- SIMILARITY: Belongs to the mycobacterial PPE family. {ECO:0000305}.
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DR   EMBL; AL123456; CCP45144.1; -; Genomic_DNA.
DR   PIR; E70663; E70663.
DR   RefSeq; WP_003904827.1; NZ_KK339370.1.
DR   AlphaFoldDB; P9WHZ7; -.
DR   SMR; P9WHZ7; -.
DR   STRING; 83332.Rv2356c; -.
DR   PaxDb; P9WHZ7; -.
DR   GeneID; 45426343; -.
DR   PATRIC; fig|83332.111.peg.2628; -.
DR   TubercuList; Rv2356c; -.
DR   eggNOG; COG5651; Bacteria.
DR   OMA; AGDYNFG; -.
DR   PhylomeDB; P9WHZ7; -.
DR   Proteomes; UP000001584; Chromosome.
DR   GO; GO:0052572; P:response to host immune response; IBA:GO_Central.
DR   Gene3D; 1.20.1260.20; -; 1.
DR   InterPro; IPR002989; Mycobac_pentapep.
DR   InterPro; IPR000030; PPE_family.
DR   InterPro; IPR038332; PPE_sf.
DR   Pfam; PF01469; Pentapeptide_2; 6.
DR   Pfam; PF00823; PPE; 1.
PE   1: Evidence at protein level;
KW   Reference proteome.
FT   CHAIN           1..615
FT                   /note="Uncharacterized PPE family protein PPE40"
FT                   /id="PRO_0000379115"
SQ   SEQUENCE   615 AA;  58390 MW;  4F9DC5241A171649 CRC64;
     MVNFSVLPPE INSGRMFFGA GSGPMLAAAA AWDGLAAELG LAAESFGLVT SGLAGGSGQA
     WQGAAAAAMV VAAAPYAGWL AAAAARAGGA AVQAKAVAGA FEAARAAMVD PVVVAANRSA
     FVQLVLSNVF GQNAPAIAAA EATYEQMWAA DVAAMVGYHG GASAAAAALA PWQQAVPGLS
     GLLGGAANAP AAAAQGAAQG LAELTLNLGV GNIGSLNLGS GNIGGTNVGS GNVGGTNLGS
     GNYGSLNWGS GNTGTGNAGS GNTGDYNPGS GNFGSGNFGS GNIGSLNVGS GNFGTLNLAN
     GNNGDVNFGG GNTGDFNFGG GNNGTLNFGF GNTGSGNFGF GNTGNNNIGI GLTGDGQIGI
     GGLNSGTGNI GFGNSGNNNI GFFNSGDGNI GFFNSGDGNT GFGNAGNINT GFWNAGNLNT
     GFGSAGNGNV GIFDGGNSNS GSFNVGFQNT GFGNSGAGNT GFFNAGDSNT GFANAGNVNT
     GFFNGGDINT GGFNGGNVNT GFGSALTQAG ANSGFGNLGT GNSGWGNSDP SGTGNSGFFN
     TGNGNSGFSN AGPAMLPGFN SGFANIGSFN AGIANSGNNL AGISNSGDDS SGAVNSGSQN
     SGAFNAGVGL SGFFR