PPE51_MYCTU
ID PPE51_MYCTU Reviewed; 380 AA.
AC P9WHY3; L0TD92; Q6MX06; Q7D623;
DT 16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT 16-APR-2014, sequence version 1.
DT 03-AUG-2022, entry version 32.
DE RecName: Full=Uncharacterized PPE family protein PPE51;
GN Name=PPE51; OrderedLocusNames=Rv3136;
OS Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium tuberculosis complex.
OX NCBI_TaxID=83332;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25618 / H37Rv;
RX PubMed=9634230; DOI=10.1038/31159;
RA Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA Barrell B.G.;
RT "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT genome sequence.";
RL Nature 393:537-544(1998).
RN [2]
RP ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1, AND IDENTIFICATION BY MASS
RP SPECTROMETRY [LARGE SCALE ANALYSIS].
RC STRAIN=ATCC 25618 / H37Rv;
RX PubMed=21969609; DOI=10.1074/mcp.m111.011627;
RA Kelkar D.S., Kumar D., Kumar P., Balakrishnan L., Muthusamy B., Yadav A.K.,
RA Shrivastava P., Marimuthu A., Anand S., Sundaram H., Kingsbury R.,
RA Harsha H.C., Nair B., Prasad T.S., Chauhan D.S., Katoch K., Katoch V.M.,
RA Kumar P., Chaerkady R., Ramachandran S., Dash D., Pandey A.;
RT "Proteogenomic analysis of Mycobacterium tuberculosis by high resolution
RT mass spectrometry.";
RL Mol. Cell. Proteomics 10:M111.011627-M111.011627(2011).
CC -!- SIMILARITY: Belongs to the mycobacterial PPE family. {ECO:0000305}.
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DR EMBL; AL123456; CCP45946.1; -; Genomic_DNA.
DR PIR; A70646; A70646.
DR RefSeq; WP_003416381.1; NZ_NVQJ01000019.1.
DR RefSeq; YP_177935.1; NC_000962.3.
DR AlphaFoldDB; P9WHY3; -.
DR SMR; P9WHY3; -.
DR STRING; 83332.Rv3136; -.
DR TCDB; 1.B.94.1.1; the pro-pro-glu outer membrane porin (ppe) family.
DR iPTMnet; P9WHY3; -.
DR PaxDb; P9WHY3; -.
DR DNASU; 888835; -.
DR GeneID; 888835; -.
DR KEGG; mtu:Rv3136; -.
DR TubercuList; Rv3136; -.
DR eggNOG; COG5651; Bacteria.
DR OMA; SAPYNME; -.
DR PhylomeDB; P9WHY3; -.
DR Proteomes; UP000001584; Chromosome.
DR GO; GO:0009274; C:peptidoglycan-based cell wall; HDA:MTBBASE.
DR GO; GO:0052572; P:response to host immune response; IBA:GO_Central.
DR Gene3D; 1.20.1260.20; -; 1.
DR InterPro; IPR022171; PPE_C.
DR InterPro; IPR000030; PPE_family.
DR InterPro; IPR038332; PPE_sf.
DR Pfam; PF00823; PPE; 1.
DR Pfam; PF12484; PPE-SVP; 1.
PE 1: Evidence at protein level;
KW Acetylation; Reference proteome.
FT CHAIN 1..380
FT /note="Uncharacterized PPE family protein PPE51"
FT /id="PRO_0000378485"
FT MOD_RES 1
FT /note="N-acetylmethionine"
FT /evidence="ECO:0007744|PubMed:21969609"
SQ SEQUENCE 380 AA; 37980 MW; 345B1EF9EC9AE4AA CRC64;
MDFALLPPEV NSARMYTGPG AGSLLAAAGG WDSLAAELAT TAEAYGSVLS GLAALHWRGP
AAESMAVTAA PYIGWLYTTA EKTQQTAIQA RAAALAFEQA YAMTLPPPVV AANRIQLLAL
IATNFFGQNT AAIAATEAQY AEMWAQDAAA MYGYATASAA AALLTPFSPP RQTTNPAGLT
AQAAAVSQAT DPLSLLIETV TQALQALTIP SFIPEDFTFL DAIFAGYATV GVTQDVESFV
AGTIGAESNL GLLNVGDENP AEVTPGDFGI GELVSATSPG GGVSASGAGG AASVGNTVLA
SVGRANSIGQ LSVPPSWAAP STRPVSALSP AGLTTLPGTD VAEHGMPGVP GVPVAAGRAS
GVLPRYGVRL TVMAHPPAAG