ID   PPE63_MYCTO             Reviewed;         479 AA.
AC   P9WHX4; L0TFR2; Q6MWW1; Q7D5B9;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 32.
DE   RecName: Full=Uncharacterized PPE family protein PPE63;
GN   Name=PPE63; OrderedLocusNames=MT3643;
OS   Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA   Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA   Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA   Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA   Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA   Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT   "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT   laboratory strains.";
RL   J. Bacteriol. 184:5479-5490(2002).
CC   -!- SIMILARITY: Belongs to the mycobacterial PPE family. {ECO:0000305}.
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DR   EMBL; AE000516; AAK48002.1; -; Genomic_DNA.
DR   PIR; D70676; D70676.
DR   RefSeq; WP_003900090.1; NZ_KK341227.1.
DR   AlphaFoldDB; P9WHX4; -.
DR   SMR; P9WHX4; -.
DR   ESTHER; myctu-ppe63; PE-PPE.
DR   EnsemblBacteria; AAK48002; AAK48002; MT3643.
DR   KEGG; mtc:MT3643; -.
DR   PATRIC; fig|83331.31.peg.3924; -.
DR   HOGENOM; CLU_028265_3_0_11; -.
DR   Proteomes; UP000001020; Chromosome.
DR   Gene3D; 1.20.1260.20; -; 1.
DR   Gene3D; 3.40.50.1820; -; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR013228; PE-PPE_C.
DR   InterPro; IPR000030; PPE_family.
DR   InterPro; IPR038332; PPE_sf.
DR   Pfam; PF08237; PE-PPE; 1.
DR   Pfam; PF00823; PPE; 1.
PE   3: Inferred from homology;
FT   CHAIN           1..479
FT                   /note="Uncharacterized PPE family protein PPE63"
FT                   /id="PRO_0000428106"
FT   DOMAIN          240..462
FT                   /note="PE-PPE"
FT                   /evidence="ECO:0000255"
FT   REGION          180..203
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        186..203
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   479 AA;  49970 MW;  271745FB45473C92 CRC64;
     MADFLTLSPE VNSARMYAGG GPGSLSAAAA AWDELAAELW LAAASFESVC SGLADRWWQG
     PSSRMMAAQA ARHTGWLAAA ATQAEGAASQ AQTMALAYEA AFAATVHPAL VAANRALVAW
     LAGSNVFGQN TPAIAAAEAI YEQMWAQDVV AMLNYHAVAS AVGARLRPWQ QLLHELPRRL
     GGEHSDSTNT ELANPSSTTT RITVPGASPV HAATLLPFIG RLLAARYAEL NTAIGTNWFP
     GTTPEVVSYP ATIGVLSGSL GAVDANQSIA IGQQMLHNEI LAATASGQPV TVAGLSMGSM
     VIDRELAYLA IDPNAPPSSA LTFVELAGPE RGLAQTYLPV GTTIPIAGYT VGNAPESQYN
     TSVVYSQYDI WADPPDRPWN LLAGANALMG AAYFHDLTAY AAPQQGIEIA AVTSSLGGTT
     TTYMIPSPTL PLLLPLKQIG VPDWIVGGLN NVLKPLVDAG YSQYAPTAGP YFSHGNLVW