ID   PPE65_MYCTU             Reviewed;         413 AA.
AC   P9WHX3; L0TDB9; Q6MWV5; Q7D569;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   03-AUG-2022, entry version 31.
DE   RecName: Full=Uncharacterized PPE family protein PPE65;
GN   Name=PPE65; OrderedLocusNames=Rv3621c;
OS   Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83332;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=9634230; DOI=10.1038/31159;
RA   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA   Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA   Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA   Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA   Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA   Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA   Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA   Barrell B.G.;
RT   "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT   genome sequence.";
RL   Nature 393:537-544(1998).
CC   -!- SIMILARITY: Belongs to the mycobacterial PPE family. {ECO:0000305}.
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DR   EMBL; AL123456; CCP46444.1; -; Genomic_DNA.
DR   PIR; F70560; F70560.
DR   RefSeq; WP_003900723.1; NZ_NVQJ01000045.1.
DR   RefSeq; YP_177998.1; NC_000962.3.
DR   AlphaFoldDB; P9WHX3; -.
DR   SMR; P9WHX3; -.
DR   STRING; 83332.Rv3621c; -.
DR   TCDB; 1.B.94.1.4; the pro-pro-glu outer membrane porin (ppe) family.
DR   PaxDb; P9WHX3; -.
DR   DNASU; 885097; -.
DR   GeneID; 45427607; -.
DR   GeneID; 885097; -.
DR   KEGG; mtu:Rv3621c; -.
DR   TubercuList; Rv3621c; -.
DR   eggNOG; COG5651; Bacteria.
DR   OMA; LTDGPWQ; -.
DR   PhylomeDB; P9WHX3; -.
DR   Proteomes; UP000001584; Chromosome.
DR   GO; GO:0052572; P:response to host immune response; IBA:GO_Central.
DR   Gene3D; 1.20.1260.20; -; 1.
DR   InterPro; IPR022171; PPE_C.
DR   InterPro; IPR000030; PPE_family.
DR   InterPro; IPR038332; PPE_sf.
DR   Pfam; PF00823; PPE; 1.
DR   Pfam; PF12484; PPE-SVP; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..413
FT                   /note="Uncharacterized PPE family protein PPE65"
FT                   /id="PRO_0000378487"
SQ   SEQUENCE   413 AA;  40680 MW;  DAAFE8917A3900A3 CRC64;
     MLDFAQLPPE VNSALMYAGP GSGPMLAAAA AWEALAAELQ TTASTYDALI TGLADGPWQG
     SSAASMVAAA TPQVAWLRST AGQAEQAGSQ AVAAASAYEA AFFATVPPPE IAANRALLMA
     LLATNFLGQN TAAIAATEAQ YAEMWAQDAA AMYGYAGASA AATQLSPFNP AAQTINPAGL
     ASQAASVGQA VSGAANAQAL TDIPKALFGL SGIFTNEPPW LTDLGKALGL TGHTWSSDGS
     GLIVGGVLGD FVQGVTGSAE LDASVAMDTF GKWVSPARLM VTQFKDYFGL AHDLPKWASE
     GAKAAGEAAK ALPAAVPAIP SAGLSGVAGA VGQAASVGGL KVPAVWTATT PAASPAVLAA
     SNGLGAAAAA EGSTHAFGGM PLMGSGAGRA FNNFAAPRYG FKPTVIAQPP AGG