PPH_MYCGE
ID PPH_MYCGE Reviewed; 260 AA.
AC P47354;
DT 01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1996, sequence version 1.
DT 03-AUG-2022, entry version 122.
DE RecName: Full=Putative protein phosphatase;
DE EC=3.1.3.16;
GN OrderedLocusNames=MG108;
OS Mycoplasma genitalium (strain ATCC 33530 / DSM 19775 / NCTC 10195 / G37)
OS (Mycoplasmoides genitalium).
OC Bacteria; Tenericutes; Mollicutes; Mycoplasmataceae; Mycoplasma.
OX NCBI_TaxID=243273;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 33530 / DSM 19775 / NCTC 10195 / G37;
RX PubMed=7569993; DOI=10.1126/science.270.5235.397;
RA Fraser C.M., Gocayne J.D., White O., Adams M.D., Clayton R.A.,
RA Fleischmann R.D., Bult C.J., Kerlavage A.R., Sutton G.G., Kelley J.M.,
RA Fritchman J.L., Weidman J.F., Small K.V., Sandusky M., Fuhrmann J.L.,
RA Nguyen D.T., Utterback T.R., Saudek D.M., Phillips C.A., Merrick J.M.,
RA Tomb J.-F., Dougherty B.A., Bott K.F., Hu P.-C., Lucier T.S.,
RA Peterson S.N., Smith H.O., Hutchison C.A. III, Venter J.C.;
RT "The minimal gene complement of Mycoplasma genitalium.";
RL Science 270:397-403(1995).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 200-260.
RC STRAIN=ATCC 33530 / DSM 19775 / NCTC 10195 / G37;
RX PubMed=8253680; DOI=10.1128/jb.175.24.7918-7930.1993;
RA Peterson S.N., Hu P.-C., Bott K.F., Hutchison C.A. III;
RT "A survey of the Mycoplasma genitalium genome by using random sequencing.";
RL J. Bacteriol. 175:7918-7930(1993).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + O-phospho-L-seryl-[protein] = L-seryl-[protein] +
CC phosphate; Xref=Rhea:RHEA:20629, Rhea:RHEA-COMP:9863, Rhea:RHEA-
CC COMP:11604, ChEBI:CHEBI:15377, ChEBI:CHEBI:29999, ChEBI:CHEBI:43474,
CC ChEBI:CHEBI:83421; EC=3.1.3.16;
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] +
CC phosphate; Xref=Rhea:RHEA:47004, Rhea:RHEA-COMP:11060, Rhea:RHEA-
CC COMP:11605, ChEBI:CHEBI:15377, ChEBI:CHEBI:30013, ChEBI:CHEBI:43474,
CC ChEBI:CHEBI:61977; EC=3.1.3.16;
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DR EMBL; L43967; AAC71326.1; -; Genomic_DNA.
DR EMBL; U02111; AAD12384.1; -; Genomic_DNA.
DR PIR; I64211; I64211.
DR RefSeq; WP_010869334.1; NC_000908.2.
DR AlphaFoldDB; P47354; -.
DR SMR; P47354; -.
DR STRING; 243273.MG_108; -.
DR EnsemblBacteria; AAC71326; AAC71326; MG_108.
DR KEGG; mge:MG_108; -.
DR eggNOG; COG0631; Bacteria.
DR HOGENOM; CLU_034545_0_3_14; -.
DR OMA; MLNAQFF; -.
DR OrthoDB; 1835483at2; -.
DR BioCyc; MGEN243273:G1GJ2-121-MON; -.
DR Proteomes; UP000000807; Chromosome.
DR GO; GO:0017018; F:myosin phosphatase activity; IEA:UniProtKB-EC.
DR GO; GO:0006470; P:protein dephosphorylation; IBA:GO_Central.
DR CDD; cd00143; PP2Cc; 1.
DR Gene3D; 3.60.40.10; -; 1.
DR InterPro; IPR015655; PP2C.
DR InterPro; IPR036457; PPM-type_dom_sf.
DR InterPro; IPR001932; PPM-type_phosphatase_dom.
DR PANTHER; PTHR13832; PTHR13832; 1.
DR SMART; SM00331; PP2C_SIG; 1.
DR SMART; SM00332; PP2Cc; 1.
DR SUPFAM; SSF81606; SSF81606; 1.
DR PROSITE; PS51746; PPM_2; 1.
PE 4: Predicted;
KW Hydrolase; Protein phosphatase; Reference proteome.
FT CHAIN 1..260
FT /note="Putative protein phosphatase"
FT /id="PRO_0000057795"
FT DOMAIN 9..254
FT /note="PPM-type phosphatase"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01082"
SQ SEQUENCE 260 AA; 29960 MW; 5C6BBC107F2539B9 CRC64;
MQAANDHFFT GLSKKGPVRK ENQDFYGFSF NQNNLLIVVC DGLGGYKGGK IASNLVGKLF
LSLFEGFEFN QWDETTVKKW FENTLIQARF QLENCFQTVY EAQIQFARMA STLVLGILTK
SDIYIFWIGD SRAYLLFENQ AKLVTKDHNL YNQLVAMNAD EKLLLSYSNQ LLALTNTISK
ETKRPLVYGF YNTKIEQQEF LLLCSDGLYN FVEKELFFEI ITNSKNLKQA VFNLYRKSIE
NASNDNITAA LVNLQKWKQS
