ID   PPK38_SCHPO             Reviewed;         650 AA.
AC   Q9UU85;
DT   31-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   03-AUG-2022, entry version 123.
DE   RecName: Full=Protein kinase domain-containing protein ppk38;
GN   Name=ppk38; ORFNames=SPCP1E11.02;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   IDENTIFICATION.
RX   PubMed=15821139; DOI=10.1128/ec.4.4.799-813.2005;
RA   Bimbo A., Jia Y., Poh S.L., Karuturi R.K.M., den Elzen N., Peng X.,
RA   Zheng L., O'Connell M., Liu E.T., Balasubramanian M.K., Liu J.;
RT   "Systematic deletion analysis of fission yeast protein kinases.";
RL   Eukaryot. Cell 4:799-813(2005).
CC   -!- DOMAIN: The protein kinase domain is predicted to be catalytically
CC       inactive.
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DR   EMBL; CU329672; CAB54861.1; -; Genomic_DNA.
DR   PIR; T41681; T41681.
DR   RefSeq; NP_588555.1; NM_001023542.2.
DR   AlphaFoldDB; Q9UU85; -.
DR   SMR; Q9UU85; -.
DR   BioGRID; 275603; 33.
DR   STRING; 4896.SPCP1E11.02.1; -.
DR   iPTMnet; Q9UU85; -.
DR   MaxQB; Q9UU85; -.
DR   PaxDb; Q9UU85; -.
DR   PRIDE; Q9UU85; -.
DR   EnsemblFungi; SPCP1E11.02.1; SPCP1E11.02.1:pep; SPCP1E11.02.
DR   GeneID; 2539030; -.
DR   KEGG; spo:SPCP1E11.02; -.
DR   PomBase; SPCP1E11.02; ppk38.
DR   VEuPathDB; FungiDB:SPCP1E11.02; -.
DR   eggNOG; KOG1989; Eukaryota.
DR   HOGENOM; CLU_011638_3_1_1; -.
DR   InParanoid; Q9UU85; -.
DR   PhylomeDB; Q9UU85; -.
DR   Reactome; R-SPO-8856828; Clathrin-mediated endocytosis.
DR   PRO; PR:Q9UU85; -.
DR   Proteomes; UP000002485; Chromosome III.
DR   GO; GO:0030479; C:actin cortical patch; ISO:PomBase.
DR   GO; GO:0005737; C:cytoplasm; HDA:PomBase.
DR   GO; GO:0005524; F:ATP binding; ISM:PomBase.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IBA:GO_Central.
DR   GO; GO:0000147; P:actin cortical patch assembly; IBA:GO_Central.
DR   GO; GO:0007015; P:actin filament organization; IBA:GO_Central.
DR   GO; GO:0006468; P:protein phosphorylation; IBA:GO_Central.
DR   GO; GO:2000369; P:regulation of clathrin-dependent endocytosis; ISO:PomBase.
DR   GO; GO:0023052; P:signaling; IC:PomBase.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   InterPro; IPR000719; Prot_kinase_dom.
DR   InterPro; IPR008271; Ser/Thr_kinase_AS.
DR   Pfam; PF00069; Pkinase; 1.
DR   SMART; SM00220; S_TKc; 1.
DR   SUPFAM; SSF56112; SSF56112; 1.
DR   PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR   PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE   4: Predicted;
KW   Nucleotide-binding; Reference proteome.
FT   CHAIN           1..650
FT                   /note="Protein kinase domain-containing protein ppk38"
FT                   /id="PRO_0000256833"
FT   DOMAIN          33..315
FT                   /note="Protein kinase"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00159"
FT   REGION          344..442
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          517..571
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          591..616
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        370..419
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        422..437
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        532..558
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   650 AA;  72000 MW;  07963A6D4E959E12 CRC64;
     MNETNNTSLL PVSSLPSGLL PVGFSCTVEK FSVTVKRYLA EGGFSHVYLV QLVFPGKPPF
     EAVLKRIFAT DAMALRAVHE EVRTMKLVSN QKRCVSYYGS EFFRTSKNQF EVLVLLEYCP
     CGGLIDFLNT RLQVRLSEQE ILKIASDVTE AVAVMHYLKP PLIHRDLKIE NVLLAAPNSY
     KLCDFGSACH PIPGAKTAAE AKQLEYDIEK FTTWQYRCPE MINVHKGFGI DEKSDIWALG
     VLFYKLCYYT TPFEHQGLAA IMNVSYAFPT FPPYSDRLKR LISTLLQQYP WQRPNIYQTF
     CEICKMRNVP IHIYDIYNGK NVSSCNPSGS EYLQHASKLE NSGIHQSKSS VFPQPASAMK
     PMASPMLPNV NSMPYLSNGD HNNNGNTSSP VSRFSYGQHT SNVPSTQKLP SNFRVTQGAP
     PSHTYGPPPP VQPKPKISPT TPRLSTLALA DDMFSSTAKE TVPTNEAVFT GDVKSFDSQE
     SNIIESEPLS ASNASGKPRT SVNRLVDRYN HTSSLNKVAA APAPVPKPVN LKSVENPQNN
     ISAPTPSSLQ SSNAPVGLGE VESKSVPPTN MATERGVVGR RASMSIAVNA RRVSKPEKEH
     TNPNAEQGDV IPEKPMSIKE RMNMLMTKTD YEKPKVEGYG RYTDVQQTKK