ID   PPK6_PERAM              Reviewed;          14 AA.
AC   P82693;
DT   04-MAY-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   11-DEC-2019, entry version 53.
DE   RecName: Full=Pyrokinin-6;
DE            Short=Pea-PK-6;
DE   AltName: Full=FXPRL-amide;
OS   Periplaneta americana (American cockroach) (Blatta americana).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Polyneoptera; Dictyoptera; Blattodea; Blattoidea; Blattidae;
OC   Blattinae; Periplaneta.
OX   NCBI_TaxID=6978;
RN   [1]
RP   PROTEIN SEQUENCE, AMIDATION AT LEU-14, FUNCTION, TISSUE SPECIFICITY, AND
RP   MASS SPECTROMETRY.
RC   TISSUE=Abdominal perisympathetic organs, and Corpora cardiaca;
RX   PubMed=10723010;
RX   DOI=10.1002/(sici)1096-9861(20000410)419:3<352::aid-cne7>3.0.co;2-0;
RA   Predel R., Eckert M.;
RT   "Tagma-specific distribution of FXPRLamides in the nervous system of the
RT   American cockroach.";
RL   J. Comp. Neurol. 419:352-363(2000).
CC   -!- FUNCTION: Shows a weakly myoactive action.
CC       {ECO:0000269|PubMed:10723010}.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- TISSUE SPECIFICITY: Corpora alata and to a lesser extent in abdominal
CC       perisympathetic organs. {ECO:0000269|PubMed:10723010}.
CC   -!- MASS SPECTROMETRY: Mass=1590.8; Method=MALDI;
CC       Evidence={ECO:0000269|PubMed:10723010};
CC   -!- SIMILARITY: Belongs to the pyrokinin family. {ECO:0000305}.
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DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005184; F:neuropeptide hormone activity; IEA:InterPro.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
DR   InterPro; IPR001484; Pyrokinin_CS.
DR   PROSITE; PS00539; PYROKININ; 1.
PE   1: Evidence at protein level;
KW   Amidation; Direct protein sequencing; Neuropeptide; Secreted.
FT   PEPTIDE         1..14
FT                   /note="Pyrokinin-6"
FT                   /id="PRO_0000044359"
FT   MOD_RES         14
FT                   /note="Leucine amide"
FT                   /evidence="ECO:0000269|PubMed:10723010"
SQ   SEQUENCE   14 AA;  1592 MW;  3966CC3FF384A998 CRC64;
     SESEVPGMWF GPRL