ID   PPK_RHOPR               Reviewed;           8 AA.
AC   P85827;
DT   03-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT   03-MAR-2009, sequence version 1.
DT   11-DEC-2019, entry version 17.
DE   RecName: Full=Pyrokinin {ECO:0000303|PubMed:19137558};
DE            Short=Rhopr-PK {ECO:0000303|PubMed:19137558};
DE   AltName: Full=FXPRL-amide {ECO:0000250|UniProtKB:P82692};
OS   Rhodnius prolixus (Triatomid bug).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Paraneoptera; Hemiptera; Heteroptera; Panheteroptera;
OC   Cimicomorpha; Reduviidae; Triatominae; Rhodnius.
OX   NCBI_TaxID=13249;
RN   [1] {ECO:0000305}
RP   PROTEIN SEQUENCE, MASS SPECTROMETRY, AND AMIDATION AT LEU-8.
RC   TISSUE=Brain {ECO:0000269|PubMed:19137558};
RX   PubMed=19137558; DOI=10.1002/pmic.200800499;
RA   Ons S., Richter F., Urlaub H., Pomar R.R.;
RT   "The neuropeptidome of Rhodnius prolixus brain.";
RL   Proteomics 9:788-792(2009).
CC   -!- FUNCTION: Mediates visceral muscle contractile activity (myotropic
CC       activity). {ECO:0000250|UniProtKB:P82692}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC   -!- PTM: Position 8 could be leucine amide or isoleucine amide.
CC       {ECO:0000269|PubMed:19137558}.
CC   -!- MASS SPECTROMETRY: Mass=883.51; Method=MALDI;
CC       Evidence={ECO:0000269|PubMed:19137558};
CC   -!- SIMILARITY: Belongs to the pyrokinin family. {ECO:0000255}.
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DR   Proteomes; UP000015103; Unassembled WGS sequence.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Amidation; Direct protein sequencing; Neuropeptide; Reference proteome;
KW   Secreted.
FT   PEPTIDE         1..8
FT                   /note="Pyrokinin"
FT                   /evidence="ECO:0000269|PubMed:19137558"
FT                   /id="PRO_0000365777"
FT   MOD_RES         8
FT                   /note="Leucine amide"
FT                   /evidence="ECO:0000269|PubMed:19137558"
FT   UNSURE          8
FT                   /note="L or I"
FT                   /evidence="ECO:0000269|PubMed:19137558"
SQ   SEQUENCE   8 AA;  884 MW;  C834176DD9D77775 CRC64;
     SPPFAPRL