PPK_SARBU
ID PPK_SARBU Reviewed; 15 AA.
AC P84356;
DT 15-FEB-2005, integrated into UniProtKB/Swiss-Prot.
DT 15-FEB-2005, sequence version 1.
DT 02-JUN-2021, entry version 34.
DE RecName: Full=Pyrokinin;
DE Short=Neobu-PK;
DE AltName: Full=FXPRL-amide;
OS Sarcophaga bullata (Grey flesh fly) (Neobellieria bullata).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Oestroidea;
OC Sarcophagidae; Sarcophaga; Neobellieria.
OX NCBI_TaxID=7385;
RN [1] {ECO:0000305}
RP PROTEIN SEQUENCE, TISSUE SPECIFICITY, MASS SPECTROMETRY, AND AMIDATION AT
RP LEU-15.
RC TISSUE=Ganglion {ECO:0000269|PubMed:14706527};
RX PubMed=14706527; DOI=10.1016/j.peptides.2003.06.009;
RA Predel R., Russell W.K., Tichy S.E., Russell D.H., Nachman R.J.;
RT "Mass spectrometric analysis of putative capa-gene products in Musca
RT domestica and Neobellieria bullata.";
RL Peptides 24:1487-1491(2003).
CC -!- FUNCTION: Mediates visceral muscle contractile activity (myotropic
CC activity). {ECO:0000250|UniProtKB:P82617}.
CC -!- SUBCELLULAR LOCATION: Secreted.
CC -!- TISSUE SPECIFICITY: Dorsal ganglionic sheath of fused ventral nerve
CC cord. {ECO:0000269|PubMed:14706527}.
CC -!- MASS SPECTROMETRY: Mass=1515.8; Method=MALDI;
CC Evidence={ECO:0000269|PubMed:14706527};
CC -!- SIMILARITY: Belongs to the pyrokinin family. {ECO:0000255}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0005184; F:neuropeptide hormone activity; IEA:InterPro.
DR GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
DR InterPro; IPR001484; Pyrokinin_CS.
DR PROSITE; PS00539; PYROKININ; 1.
PE 1: Evidence at protein level;
KW Amidation; Direct protein sequencing; Neuropeptide; Secreted.
FT PEPTIDE 1..15
FT /note="Pyrokinin"
FT /id="PRO_0000044368"
FT MOD_RES 15
FT /note="Leucine amide"
FT /evidence="ECO:0000269|PubMed:14706527"
FT UNSURE 15
FT /note="L or I"
FT /evidence="ECO:0000269|PubMed:14706527"
SQ SEQUENCE 15 AA; 1517 MW; 3C70432BE394A9CD CRC64;
AGPSATTGVW FGPRL