PPR29_ARATH
ID PPR29_ARATH Reviewed; 913 AA.
AC Q9SY69;
DT 01-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 25-MAY-2022, entry version 130.
DE RecName: Full=Pentatricopeptide repeat-containing protein At1g10270;
DE AltName: Full=Protein GLUTAMINE-RICH PROTEIN 23;
GN Name=GRP23; OrderedLocusNames=At1g10270; ORFNames=F14N23.15;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP GENE FAMILY.
RX PubMed=15269332; DOI=10.1105/tpc.104.022236;
RA Lurin C., Andres C., Aubourg S., Bellaoui M., Bitton F., Bruyere C.,
RA Caboche M., Debast C., Gualberto J., Hoffmann B., Lecharny A., Le Ret M.,
RA Martin-Magniette M.-L., Mireau H., Peeters N., Renou J.-P., Szurek B.,
RA Taconnat L., Small I.;
RT "Genome-wide analysis of Arabidopsis pentatricopeptide repeat proteins
RT reveals their essential role in organelle biogenesis.";
RL Plant Cell 16:2089-2103(2004).
RN [4]
RP FUNCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, DEVELOPMENTAL STAGE,
RP AND INTERACTION WITH RPB36B.
RX PubMed=16489121; DOI=10.1105/tpc.105.039495;
RA Ding Y.-H., Liu N.-Y., Tang Z.-S., Liu J., Yang W.-C.;
RT "Arabidopsis GLUTAMINE-RICH PROTEIN23 is essential for early embryogenesis
RT and encodes a novel nuclear PPR motif protein that interacts with RNA
RT polymerase II subunit III.";
RL Plant Cell 18:815-830(2006).
CC -!- FUNCTION: May function as a transcriptional regulator essential for
CC early embryogenesis. {ECO:0000269|PubMed:16489121}.
CC -!- SUBUNIT: Interacts with RPB36B through its WQQ domain.
CC {ECO:0000269|PubMed:16489121}.
CC -!- INTERACTION:
CC Q9SY69; Q39212: NRPD3B; NbExp=3; IntAct=EBI-1769617, EBI-1769627;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:16489121}.
CC -!- TISSUE SPECIFICITY: Ubiquitous but preferentially expressed in
CC gametophytes and young embryos. {ECO:0000269|PubMed:16489121}.
CC -!- DEVELOPMENTAL STAGE: Expressed in developing embryos up to the heart
CC stage. {ECO:0000269|PubMed:16489121}.
CC -!- DOMAIN: The WQQ domain consists of a repetition of W-x(2)-Q-x(4)-Q-x(2)
CC motifs.
CC -!- SIMILARITY: Belongs to the PPR family. P subfamily. {ECO:0000305}.
CC -!- WEB RESOURCE: Name=Pentatricopeptide repeat proteins;
CC URL="https://ppr.plantenergy.uwa.edu.au";
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DR EMBL; AC005489; AAD32877.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE28560.1; -; Genomic_DNA.
DR PIR; A86237; A86237.
DR RefSeq; NP_172498.1; NM_100901.3.
DR AlphaFoldDB; Q9SY69; -.
DR SMR; Q9SY69; -.
DR BioGRID; 22806; 1.
DR IntAct; Q9SY69; 1.
DR STRING; 3702.AT1G10270.1; -.
DR PaxDb; Q9SY69; -.
DR PRIDE; Q9SY69; -.
DR ProteomicsDB; 226491; -.
DR EnsemblPlants; AT1G10270.1; AT1G10270.1; AT1G10270.
DR GeneID; 837566; -.
DR Gramene; AT1G10270.1; AT1G10270.1; AT1G10270.
DR KEGG; ath:AT1G10270; -.
DR Araport; AT1G10270; -.
DR TAIR; locus:2012868; AT1G10270.
DR eggNOG; KOG4197; Eukaryota.
DR HOGENOM; CLU_012783_2_0_1; -.
DR InParanoid; Q9SY69; -.
DR OMA; QQPWANQ; -.
DR OrthoDB; 1344243at2759; -.
DR PhylomeDB; Q9SY69; -.
DR PRO; PR:Q9SY69; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9SY69; baseline and differential.
DR Genevisible; Q9SY69; AT.
DR GO; GO:0009507; C:chloroplast; IBA:GO_Central.
DR GO; GO:0005739; C:mitochondrion; HDA:TAIR.
DR GO; GO:0005634; C:nucleus; IDA:TAIR.
DR GO; GO:0051301; P:cell division; IMP:TAIR.
DR GO; GO:0009793; P:embryo development ending in seed dormancy; IMP:TAIR.
DR Gene3D; 1.25.40.10; -; 3.
DR InterPro; IPR002885; Pentatricopeptide_repeat.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR Pfam; PF01535; PPR; 4.
DR Pfam; PF12854; PPR_1; 1.
DR SMART; SM00028; TPR; 2.
DR SUPFAM; SSF48452; SSF48452; 1.
DR TIGRFAMs; TIGR00756; PPR; 4.
DR PROSITE; PS51375; PPR; 10.
PE 1: Evidence at protein level;
KW Nucleus; Reference proteome; Repeat; Transcription;
KW Transcription regulation.
FT CHAIN 1..913
FT /note="Pentatricopeptide repeat-containing protein
FT At1g10270"
FT /id="PRO_0000342770"
FT REPEAT 179..214
FT /note="PPR 1"
FT REPEAT 215..250
FT /note="PPR 2"
FT REPEAT 251..285
FT /note="PPR 3"
FT REPEAT 286..316
FT /note="PPR 4"
FT REPEAT 321..355
FT /note="PPR 5"
FT REPEAT 356..390
FT /note="PPR 6"
FT REPEAT 396..426
FT /note="PPR 7"
FT REPEAT 435..469
FT /note="PPR 8"
FT REPEAT 470..504
FT /note="PPR 9"
FT REPEAT 505..539
FT /note="PPR 10"
FT REPEAT 540..574
FT /note="PPR 11"
FT REGION 34..138
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 134..167
FT /note="Leucine-zipper"
FT /evidence="ECO:0000255"
FT REGION 607..913
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 674..858
FT /note="14 X 11 AA approximate tandem repeats of W-x(2)-Q-
FT x(4)-Q-x(2)"
FT MOTIF 99..108
FT /note="Nuclear localization signal"
FT /evidence="ECO:0000255"
FT COMPBIAS 34..71
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 635..898
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 899..913
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 913 AA; 102093 MW; 487026FC572C3A2D CRC64;
MSLSHLLRRL CTTTTTTRSP LSISFLHQRI HNISLSPANE DPETTTGNNQ DSEKYPNLNP
IPNDPSQFQI PQNHTPPIPY PPIPHRTMAF SSAEEAAAER RRRKRRLRIE PPLHALRRDP
SAPPPKRDPN APRLPDSTSA LVGQRLNLHN RVQSLIRASD LDAASKLARQ SVFSNTRPTV
FTCNAIIAAM YRAKRYSESI SLFQYFFKQS NIVPNVVSYN QIINAHCDEG NVDEALEVYR
HILANAPFAP SSVTYRHLTK GLVQAGRIGD AASLLREMLS KGQAADSTVY NNLIRGYLDL
GDFDKAVEFF DELKSKCTVY DGIVNATFME YWFEKGNDKE AMESYRSLLD KKFRMHPPTG
NVLLEVFLKF GKKDEAWALF NEMLDNHAPP NILSVNSDTV GIMVNECFKM GEFSEAINTF
KKVGSKVTSK PFVMDYLGYC NIVTRFCEQG MLTEAERFFA EGVSRSLPAD APSHRAMIDA
YLKAERIDDA VKMLDRMVDV NLRVVADFGA RVFGELIKNG KLTESAEVLT KMGEREPKPD
PSIYDVVVRG LCDGDALDQA KDIVGEMIRH NVGVTTVLRE FIIEVFEKAG RREEIEKILN
SVARPVRNAG QSGNTPPRVP AVFGTTPAAP QQPRDRAPWT SQGVVHSNSG WANGTAGQTA
GGAYKANNGQ NPSWSNTSDN QQQQSWSNQT AGQQPPSWSR QAPGYQQQQS WSQQSGWSSP
SGHQQSWTNQ TAGQQQPWAN QTPGQQQQWA NQTPGQQQQL ANQTPGQQQQ WANQTPGQQQ
QWANQNNGHQ QPWANQNTGH QQSWANQTPS QQQPWANQTT GQQQGWGNQT TGQQQQWANQ
TAGQQSGWTA QQQWSNQTAS HQQSQWLNPV PGEVANQTPW SNSVDSHLPQ QQEPGPSHEC
QETQEKKVVE LRN
