PPR36_RAT
ID PPR36_RAT Reviewed; 411 AA.
AC Q68FW6;
DT 19-JUL-2005, integrated into UniProtKB/Swiss-Prot.
DT 11-OCT-2004, sequence version 1.
DT 03-AUG-2022, entry version 88.
DE RecName: Full=Protein phosphatase 1 regulatory subunit 36;
GN Name=Ppp1r36;
OS Rattus norvegicus (Rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Rattus.
OX NCBI_TaxID=10116;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Kidney;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- FUNCTION: Inhibits phosphatase activity of protein phosphatase 1 (PP1)
CC complexes. {ECO:0000250}.
CC -!- SUBUNIT: Interacts with PPP1CA. {ECO:0000250}.
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DR EMBL; BC079166; AAH79166.1; -; mRNA.
DR RefSeq; NP_001013966.1; NM_001013944.1.
DR AlphaFoldDB; Q68FW6; -.
DR SMR; Q68FW6; -.
DR STRING; 10116.ENSRNOP00000055437; -.
DR PaxDb; Q68FW6; -.
DR Ensembl; ENSRNOT00000058642; ENSRNOP00000055437; ENSRNOG00000038480.
DR GeneID; 299153; -.
DR KEGG; rno:299153; -.
DR UCSC; RGD:1309051; rat.
DR CTD; 145376; -.
DR RGD; 1309051; Ppp1r36.
DR eggNOG; ENOG502RH2T; Eukaryota.
DR GeneTree; ENSGT00390000012412; -.
DR HOGENOM; CLU_053706_0_0_1; -.
DR InParanoid; Q68FW6; -.
DR OMA; RDDKSPK; -.
DR OrthoDB; 1188799at2759; -.
DR PhylomeDB; Q68FW6; -.
DR PRO; PR:Q68FW6; -.
DR Proteomes; UP000002494; Chromosome 6.
DR Bgee; ENSRNOG00000038480; Expressed in testis and 19 other tissues.
DR Genevisible; Q68FW6; RN.
DR GO; GO:0019902; F:phosphatase binding; IEA:InterPro.
DR GO; GO:0004864; F:protein phosphatase inhibitor activity; IEA:UniProtKB-KW.
DR GO; GO:0010923; P:negative regulation of phosphatase activity; IEA:InterPro.
DR InterPro; IPR026142; Pro_pase_1_reg_su_36.
DR PANTHER; PTHR21055; PTHR21055; 1.
DR Pfam; PF14895; PPPI_inhib; 1.
PE 2: Evidence at transcript level;
KW Protein phosphatase inhibitor; Reference proteome.
FT CHAIN 1..411
FT /note="Protein phosphatase 1 regulatory subunit 36"
FT /id="PRO_0000089894"
SQ SEQUENCE 411 AA; 47760 MW; E14B9B8CA0B7AAB3 CRC64;
MYKGETLFSI PELYPRRKQF VGQSSTRLDQ CGLRLGMWYW KDETKSLEFR SFTPAVELKE
KGKKGKAVHF AEMDGTASER LTDKRFVPRD EKSAKTLEKR GQQGNVTLDD VKFVALLSLQ
DTEMQRVCSF TTFMRNKSLD SFLMALLYYL SYYLERLSME KKPQSYMVGL VEKKEIELVM
SKLEDAQKYL AQKYCKLVLG VGMADKHHMN CGKDKISDTQ KDWKFFESFY TFCTCIAWIV
FRRQYLKEIE EEVGRLFRTN MFNIPRRKRE DEESGGEKKR MTLVQFRRMM AKRPAIKKAM
DMRSPVLSTL LPSLREKAQH IAEKKYVAGI KLQPRVEKDI TNLESVVMPV VGILGEPRNL
FNPHTLLPLE SEENGKTSGR NSSIVERNNT SIQNTLNLVM SKLTSQNSFP K